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Aliases for KRAS Gene

Aliases for KRAS Gene

  • KRAS Proto-Oncogene, GTPase 2 3 5
  • V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog 2 3
  • Kirsten Rat Sarcoma Viral Oncogene Homolog 2 3
  • C-Ki-Ras 3 4
  • K-Ras 2 3 4
  • C-K-RAS 3 4
  • KI-RAS 3 4
  • KRAS2 3 4
  • RASK2 3 4
  • V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog 2
  • Kirsten Rat Sarcoma Viral Proto-Oncogene 3
  • Cellular Transforming Proto-Oncogene 3
  • Cellular C-Ki-Ras2 Proto-Oncogene 3
  • Transforming Protein P21 3
  • PR310 C-K-Ras Oncogene 3
  • C-Kirsten-Ras Protein 3
  • K-Ras P21 Protein 3
  • Oncogene KRAS2 3
  • GTPase KRas 3
  • C-Ki-Ras2 3
  • K-RAS2A 3
  • K-RAS2B 3
  • K-RAS4A 3
  • K-RAS4B 3
  • K-Ras 3
  • KRAS1 3
  • CFC2 3
  • RALD 3
  • NS3 3
  • NS 3

External Ids for KRAS Gene

Previous HGNC Symbols for KRAS Gene

  • KRAS2

Previous GeneCards Identifiers for KRAS Gene

  • GC12M025250
  • GC12M025358
  • GC12M025128

Summaries for KRAS Gene

Entrez Gene Summary for KRAS Gene

  • This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

CIViC summary for KRAS Gene

  • Mutations in the RAS family of proteins are frequently observed across cancer types. The amino acid positions that account for the overwhelming majority of these mutations are G12, G13 and Q61. The different protein isoforms, despite their raw similarity, also behave very differently when expressed in non-native tissue types, likely due to differences in the C-terminal hyper-variable regions. Mis-regulation of isoform expression has been shown to be a driving event in cancer, as well as missense mutations at the three hotspots previously mentioned. While highly recurrent in cancer, attempts to target these RAS mutants with inhibitors have not been successful, and has not yet become common practice in the clinic. The prognostic implications for KRAS mutations vary between cancer types, but have been shown to be associated with poor outcome in colorectal cancer, non-small cell lung cancer, and others.

GeneCards Summary for KRAS Gene

KRAS (KRAS Proto-Oncogene, GTPase) is a Protein Coding gene. Diseases associated with KRAS include Ras-Associated Autoimmune Leukoproliferative Disorder and Noonan Syndrome 3. Among its related pathways are RET signaling and NFAT and Cardiac Hypertrophy. Gene Ontology (GO) annotations related to this gene include GTP binding and protein complex binding. An important paralog of this gene is NRAS.

UniProtKB/Swiss-Prot for KRAS Gene

  • Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).

Gene Wiki entry for KRAS Gene

PharmGKB "VIP" Summary for KRAS Gene

Additional gene information for KRAS Gene

No data available for Tocris Summary , fRNAdb sequence ontologies and piRNA Summary for KRAS Gene

Genomics for KRAS Gene

GeneHancer (GH) Regulatory Elements for KRAS Gene

Promoters and enhancers for KRAS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I025249 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 552 +0.0 11 2.6 FOXA2 ARID4B SIN3A YY1 ZNF143 SP3 SP5 REST KAT8 ZNF610 KRAS CASC1 LRMP PIR52766
GH12I025194 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 14.3 +55.4 55430 2.8 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 POLR2B E2F8 CASC1 ETFRF1 KRAS RASSF8-AS1 ENSG00000274987 GC12M025195
GH12I025383 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 13.7 -135.0 -134981 4.1 PKNOX1 FOXA2 SMAD1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ENSG00000278743 KRAS GC12M025381 GC12P025376
GH12I025275 Enhancer 1.2 Ensembl ENCODE 12.1 -25.5 -25474 1.2 PKNOX1 ATF1 FOXA2 BRCA1 YY1 NCOA2 TCF12 ZNF766 GLIS2 FOS RASSF8-AS1 KRAS PIR53457
GH12I025381 Enhancer 0.9 Ensembl ENCODE dbSUPER 12.8 -131.9 -131855 1.8 KLF1 ZNF687 ZNF449 SPI1 GC12M025381 KRAS GC12M025379 GC12P025376
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around KRAS on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KRAS gene promoter:

Genomic Locations for KRAS Gene

Genomic Locations for KRAS Gene
chr12:25,204,789-25,250,936
(GRCh38/hg38)
Size:
46,148 bases
Orientation:
Minus strand
chr12:25,357,723-25,403,870
(GRCh37/hg19)

Genomic View for KRAS Gene

Genes around KRAS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KRAS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KRAS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KRAS Gene

Proteins for KRAS Gene

  • Protein details for KRAS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01116-RASK_HUMAN
    Recommended name:
    GTPase KRas
    Protein Accession:
    P01116
    Secondary Accessions:
    • A8K8Z5
    • B0LPF9
    • P01118
    • Q96D10

    Protein attributes for KRAS Gene

    Size:
    189 amino acids
    Molecular mass:
    21656 Da
    Quaternary structure:
    • Interacts with PHLPP. Interacts (active GTP-bound form preferentially) with RGS14 (By similarity). Interacts (when farnesylated) with PDE6D; this promotes dissociation from the cell membrane (PubMed:23698361). Interacts with SOS1 (PubMed:22431598).

    Three dimensional structures from OCA and Proteopedia for KRAS Gene

    Alternative splice isoforms for KRAS Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KRAS Gene

Post-translational modifications for KRAS Gene

  • Acetylation at Lys-104 prevents interaction with guanine nucleotide exchange factors (GEFs).
  • Ubiquitination at posLast=8888, isoforms=2117, and posLast=128128
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for KRAS Gene

Domains & Families for KRAS Gene

Gene Families for KRAS Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for KRAS Gene

Graphical View of Domain Structure for InterPro Entry

P01116

UniProtKB/Swiss-Prot:

RASK_HUMAN :
  • Belongs to the small GTPase superfamily. Ras family.
Family:
  • Belongs to the small GTPase superfamily. Ras family.
genes like me logo Genes that share domains with KRAS: view

Function for KRAS Gene

Molecular function for KRAS Gene

UniProtKB/Swiss-Prot EnzymeRegulation:
Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP). Interaction with SOS1 promotes exchange of bound GDP by GTP.
UniProtKB/Swiss-Prot Function:
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).

Phenotypes From GWAS Catalog for KRAS Gene

Gene Ontology (GO) - Molecular Function for KRAS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003924 GTPase activity IEA --
GO:0005515 protein binding IPI 12732644
GO:0005525 GTP binding IEA --
GO:0019002 GMP binding IEA --
genes like me logo Genes that share ontologies with KRAS: view
genes like me logo Genes that share phenotypes with KRAS: view

Human Phenotype Ontology for KRAS Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for KRAS Gene

MGI Knock Outs for KRAS:

miRNA for KRAS Gene

miRTarBase miRNAs that target KRAS

Clone Products

  • Addgene plasmids for KRAS

Cell Line Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for KRAS Gene

Localization for KRAS Gene

Subcellular locations from UniProtKB/Swiss-Prot for KRAS Gene

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KRAS gene
Compartment Confidence
plasma membrane 5
cytosol 5
mitochondrion 4
nucleus 3
extracellular 2
cytoskeleton 2
endoplasmic reticulum 2
endosome 2
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for KRAS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA,IDA 23698361
GO:0005739 mitochondrion IEA --
GO:0005829 cytosol IEA --
GO:0005886 plasma membrane TAS --
GO:0005925 focal adhesion IDA,HDA 21423176
genes like me logo Genes that share ontologies with KRAS: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for KRAS Gene

Pathways & Interactions for KRAS Gene

SuperPathway Contained pathways
1 RET signaling
2 Downstream signaling of activated FGFR2
3 IL-2 Pathway
4 Endometrial cancer
.52
.47
5 Common Cytokine Receptor Gamma-Chain Family Signaling Pathways
genes like me logo Genes that share pathways with KRAS: view

Pathways by source for KRAS Gene

SIGNOR curated interactions for KRAS Gene

Gene Ontology (GO) - Biological Process for KRAS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000165 MAPK cascade TAS --
GO:0001889 liver development IEA --
GO:0001934 positive regulation of protein phosphorylation IMP 22065586
GO:0002223 stimulatory C-type lectin receptor signaling pathway TAS --
GO:0007165 signal transduction IEA --
genes like me logo Genes that share ontologies with KRAS: view

Drugs & Compounds for KRAS Gene

(113) Drugs for KRAS Gene - From: DrugBank, PharmGKB, ClinicalTrials, ApexBio, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Cetuximab Approved Pharma Antibody, Biomarker, inhibitor EGFR Inhibitors, Therapeutic Antibodies, Epidermal growth factor receptor (EGFR) inhibitors 784
Trametinib Approved Pharma inhibitor, Biomarker MEK 1/2 inhibitor, MEK Inhibitors, Kinase Inhibitors, Mitogen-activated protein/extracellular signal-regulated kinase (MEK) inhibitors 151
Panitumumab Approved, Investigational Pharma inhibitor, Biomarker, antibody EGFR inhibitor, EGFR Inhibitors, Therapeutic Antibodies, Epidermal growth factor receptor (EGFR) inhibitors 0
leucovorin Approved Nutra 3402,1193
regorafenib Approved Pharma inhibitor Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1, Kinase Inhibitors, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors 0

(18) Additional Compounds for KRAS Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs

(9) ApexBio Compounds for KRAS Gene

Compound Action Cas Number
6H05
AMG-47A destabilizer of the KRAS oncoprotein 882663-88-9
Deltarasin KRAS-PDEδ interaction inhibitor 1440898-61-2
Deltarasin hydrochloride inhibitor of KRAS-PDEδ interaction, potent and selective 1440898-82-7
Kobe0065 Ras inhibitor 436133-68-5
kobe2602 Ras inhibitor 454453-49-7
K-Ras(G12C) inhibitor 12 1469337-95-8
K-Ras(G12C) inhibitor 6 K-Ras (G12C) inhibitor
Salirasib Inhibitor of active Ras protein 162520-00-5
genes like me logo Genes that share compounds with KRAS: view

Drug Products

Transcripts for KRAS Gene

Unigene Clusters for KRAS Gene

V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog:
Representative Sequences:

Clone Products

  • Addgene plasmids for KRAS

Alternative Splicing Database (ASD) splice patterns (SP) for KRAS Gene

No ASD Table

Relevant External Links for KRAS Gene

GeneLoc Exon Structure for
KRAS
ECgene alternative splicing isoforms for
KRAS

Expression for KRAS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KRAS Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KRAS Gene

This gene is overexpressed in Brain (12.2) and Tlymphocyte (8.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KRAS Gene



Protein tissue co-expression partners for KRAS Gene

NURSA nuclear receptor signaling pathways regulating expression of KRAS Gene:

KRAS

SOURCE GeneReport for Unigene cluster for KRAS Gene:

Hs.505033

Evidence on tissue expression from TISSUES for KRAS Gene

  • Lung(4.7)
  • Nervous system(4.7)
  • Intestine(3.8)
  • Thyroid gland(3.3)
  • Liver(3.2)
  • Pancreas(3.1)
  • Blood(2.9)
  • Lymph node(2.9)
  • Gall bladder(2.8)
  • Kidney(2.7)
  • Skin(2.5)
  • Spleen(2.5)
  • Stomach(2.5)
  • Bone marrow(2.3)
  • Heart(2.1)
  • Muscle(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for KRAS Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cerebellum
  • cerebrospinal fluid
  • cheek
  • chin
  • cranial nerve
  • ear
  • epiglottis
  • eye
  • eyelid
  • face
  • forehead
  • head
  • jaw
  • larynx
  • lip
  • mandible
  • maxilla
  • meninges
  • mouth
  • neck
  • nose
  • outer ear
  • scalp
  • skull
  • thyroid
  • tongue
  • tooth
  • vocal cord
Thorax:
  • aorta
  • breast
  • chest wall
  • clavicle
  • esophagus
  • heart
  • heart valve
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
  • trachea
Abdomen:
  • abdominal wall
  • biliary tract
  • gallbladder
  • intestine
  • kidney
  • large intestine
  • liver
  • pancreas
  • small intestine
  • spleen
  • stomach
Pelvis:
  • anus
  • ovary
  • pelvis
  • placenta
  • rectum
  • testicle
  • ureter
  • urethra
  • urinary bladder
  • uterus
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • nail
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • bone marrow
  • coagulation system
  • hair
  • lymph node
  • lymph vessel
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal column
  • spinal cord
  • sweat gland
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with KRAS: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KRAS Gene

Orthologs for KRAS Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for KRAS Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KRAS 33 34
  • 99.82 (n)
dog
(Canis familiaris)
Mammalia KRAS 33
  • 98.59 (n)
K-RAS 34
  • 91 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KRAS 33 34
  • 95.21 (n)
oppossum
(Monodelphis domestica)
Mammalia KRAS 34
  • 91 (a)
OneToMany
-- 34
  • 90 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia KRAS 34
  • 91 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Kras 33
  • 87.77 (n)
mouse
(Mus musculus)
Mammalia Kras 33 16 34
  • 87.06 (n)
chicken
(Gallus gallus)
Aves KRAS 33 34
  • 83.69 (n)
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 89 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485959 33
  • 80.95 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.24980 33
zebrafish
(Danio rerio)
Actinopterygii kras 33 34
  • 74.82 (n)
fruit fly
(Drosophila melanogaster)
Insecta Ras85D 33 34
  • 70.71 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002219 33
  • 69.7 (n)
worm
(Caenorhabditis elegans)
Secernentea let-60 33 34
  • 65.58 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RAS1 34
  • 35 (a)
ManyToMany
RAS2 34
  • 34 (a)
ManyToMany
Species where no ortholog for KRAS was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KRAS Gene

ENSEMBL:
Gene Tree for KRAS (if available)
TreeFam:
Gene Tree for KRAS (if available)

Paralogs for KRAS Gene

Paralogs for KRAS Gene

genes like me logo Genes that share paralogs with KRAS: view

Variants for KRAS Gene

Sequence variations from dbSNP and Humsavar for KRAS Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1046727392 uncertain-significance, Cardio-facio-cutaneous syndrome, Noonan syndrome 25,250,919(-) C/T 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant
rs104886027 not-provided, Sarcoma 25,227,305(-) C/T coding_sequence_variant, genic_downstream_transcript_variant, synonymous_variant
rs104886028 not-provided, Sarcoma 25,227,308(-) C/T coding_sequence_variant, genic_downstream_transcript_variant, missense_variant
rs104886029 not-provided, Familial cancer of breast 25,227,348(-) G/A coding_sequence_variant, genic_downstream_transcript_variant, missense_variant
rs104894359 pathogenic, Cardiofaciocutaneous syndrome 2, Rasopathy, not provided, Cardio-facio-cutaneous syndrome, Noonan syndrome 3, Noonan syndrome 3 (NS3) [MIM:609942], Cardiofaciocutaneous syndrome 2 (CFC2) [MIM:615278] 25,227,346(-) C/G/T coding_sequence_variant, genic_downstream_transcript_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for KRAS Gene

Variant ID Type Subtype PubMed ID
esv3580196 CNV loss 25503493
esv3628892 CNV loss 21293372
nsv1048631 CNV loss 25217958
nsv470279 CNV gain 18288195
nsv522233 CNV loss 19592680
nsv557798 CNV loss 21841781

Variation tolerance for KRAS Gene

Residual Variation Intolerance Score: 37.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.13; 2.86% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KRAS Gene

Human Gene Mutation Database (HGMD)
KRAS
SNPedia medical, phenotypic, and genealogical associations of SNPs for
KRAS

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KRAS Gene

Disorders for KRAS Gene

MalaCards: The human disease database

(125) MalaCards diseases for KRAS Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards