Aliases for ANOS1 Gene
External Ids for ANOS1 Gene
Previous HGNC Symbols for ANOS1 Gene
Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008]
GeneCards Summary for ANOS1 Gene
ANOS1 (Anosmin 1) is a Protein Coding gene. Diseases associated with ANOS1 include Hypogonadotropic Hypogonadism 1 With Or Without Anosmia and Anos1-Related Isolated Gonadotropin-Releasing Hormone Deficiency. Among its related pathways are Negative regulation of FGFR1 signaling and Signaling by FGFR2. GO annotations related to this gene include heparin binding and extracellular matrix structural constituent.
UniProtKB/Swiss-Prot for ANOS1 Gene
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.