Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CYP4B1 Gene

Aliases for CYP4B1 Gene

  • Cytochrome P450 Family 4 Subfamily B Member 1 2 3 5
  • Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 2 3
  • Cytochrome P450, Subfamily IVB, Polypeptide 1 2 3
  • Cytochrome P450-HP 3 4
  • CYPIVB1 3 4
  • Microsomal Monooxygenase 3
  • Cytochrome P450 4B1 3
  • EC 1.14.14.1 4
  • P-450HP 3

External Ids for CYP4B1 Gene

Previous GeneCards Identifiers for CYP4B1 Gene

  • GC01P046958
  • GC01P046221
  • GC01P046651
  • GC01P046634
  • GC01P046976
  • GC01P047037
  • GC01P047264
  • GC01P045380
  • GC01P047227

Summaries for CYP4B1 Gene

Entrez Gene Summary for CYP4B1 Gene

  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]

GeneCards Summary for CYP4B1 Gene

CYP4B1 (Cytochrome P450 Family 4 Subfamily B Member 1) is a Protein Coding gene. Diseases associated with CYP4B1 include Bladder Cancer. Among its related pathways are Cytochrome P450 - arranged by substrate type and Metabolism. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP4A11.

UniProtKB/Swiss-Prot for CYP4B1 Gene

  • Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Gene Wiki entry for CYP4B1 Gene

Additional gene information for CYP4B1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP4B1 Gene

Genomics for CYP4B1 Gene

GeneHancer (GH) Regulatory Elements for CYP4B1 Gene

Promoters and enhancers for CYP4B1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J046757 Enhancer 0.9 ENCODE dbSUPER 650.7 +0.5 533 2.6 SIX4 PKNOX1 ESRRA NFIB NEUROD1 CTBP1 GATA3 POLR2A RFX1 HLF CYP4B1 EFCAB14 LOC105378699 GC01M046749 GC01P046743
GH01J046798 Promoter/Enhancer 0.7 EPDnew dbSUPER 663.7 +41.2 41189 0.1 CYP4B1 GC01M046749 LOC100533627
GH01J046717 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.8 -39.1 -39053 3.3 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 EFCAB14 PIR52630 LRRC41 EFCAB14-AS1 NSUN4 LINC01389 TEX38 CYP4B1 MOB3C ATPAF1
GH01J046338 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.6 -416.3 -416290 5.5 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC NSUN4 LRRC41 GPBP1L1 LURAP1 RPL7AP16 EFCAB14-AS1 UQCRH RPS15AP10 MOB3C PIK3R3
GH01J046804 Enhancer 1 Ensembl ENCODE dbSUPER 23.2 +48.3 48310 4.2 PKNOX1 CLOCK HLF MAX CEBPB REST NR2F2 SP1 GATA3 CREB1 CYP4B1 CYP4A11 CYP4X1 GC01M046749 LOC100533627
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CYP4B1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CYP4B1 gene promoter:

Genomic Locations for CYP4B1 Gene

Genomic Locations for CYP4B1 Gene
chr1:46,757,838-46,819,413
(GRCh38/hg38)
Size:
61,576 bases
Orientation:
Plus strand
chr1:47,223,510-47,285,085
(GRCh37/hg19)

Genomic View for CYP4B1 Gene

Genes around CYP4B1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYP4B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYP4B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYP4B1 Gene

Proteins for CYP4B1 Gene

  • Protein details for CYP4B1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P13584-CP4B1_HUMAN
    Recommended name:
    Cytochrome P450 4B1
    Protein Accession:
    P13584
    Secondary Accessions:
    • Q1HBI2
    • Q8TD85
    • Q8WWF2
    • Q8WWU9
    • Q8WWV0

    Protein attributes for CYP4B1 Gene

    Size:
    511 amino acids
    Molecular mass:
    58991 Da
    Cofactor:
    Name=heme; Xref=ChEBI:CHEBI:30413;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CYP4B1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CYP4B1 Gene

Post-translational modifications for CYP4B1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CYP4B1 Gene

Domains & Families for CYP4B1 Gene

Gene Families for CYP4B1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for CYP4B1 Gene

Suggested Antigen Peptide Sequences for CYP4B1 Gene

Graphical View of Domain Structure for InterPro Entry

P13584

UniProtKB/Swiss-Prot:

CP4B1_HUMAN :
  • Belongs to the cytochrome P450 family.
Family:
  • Belongs to the cytochrome P450 family.
genes like me logo Genes that share domains with CYP4B1: view

Function for CYP4B1 Gene

Molecular function for CYP4B1 Gene

UniProtKB/Swiss-Prot Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
UniProtKB/Swiss-Prot CatalyticActivity:
RH + [reduced NADPH--hemoprotein reductase] + O(2) = ROH + [oxidized NADPH--hemoprotein reductase] + H(2)O.
UniProtKB/Swiss-Prot Induction:
P450 can be induced to high levels in liver and other tissues by various foreign compounds, including drugs, pesticides, and carcinogens.
GENATLAS Biochemistry:
cytochrome P450,subfamily IVB1,expressed in lung

Enzyme Numbers (IUBMB) for CYP4B1 Gene

Phenotypes From GWAS Catalog for CYP4B1 Gene

Gene Ontology (GO) - Molecular Function for CYP4B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005506 iron ion binding IEA --
GO:0008144 drug binding IEA --
GO:0015643 toxic substance binding IEA --
GO:0016491 oxidoreductase activity IEA --
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA --
genes like me logo Genes that share ontologies with CYP4B1: view
genes like me logo Genes that share phenotypes with CYP4B1: view

Animal Models for CYP4B1 Gene

MGI Knock Outs for CYP4B1:
  • Cyp4b1 Cyp4b1<tm1e(KOMP)Wtsi>
  • Cyp4b1 Cyp4b1<tm1b(KOMP)Wtsi>

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYP4B1

Clone Products

No data available for Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CYP4B1 Gene

Localization for CYP4B1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYP4B1 Gene

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CYP4B1 gene
Compartment Confidence
endoplasmic reticulum 5
extracellular 2
golgi apparatus 2
plasma membrane 1
mitochondrion 1
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CYP4B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0031090 organelle membrane IEA --
genes like me logo Genes that share ontologies with CYP4B1: view

Pathways & Interactions for CYP4B1 Gene

genes like me logo Genes that share pathways with CYP4B1: view

Gene Ontology (GO) - Biological Process for CYP4B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006725 cellular aromatic compound metabolic process IEA --
GO:0018879 biphenyl metabolic process IEA --
GO:0018917 fluorene metabolic process IEA --
GO:0042738 exogenous drug catabolic process IEA --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with CYP4B1: view

No data available for SIGNOR curated interactions for CYP4B1 Gene

Drugs & Compounds for CYP4B1 Gene

(25) Drugs for CYP4B1 Gene - From: DrugBank, PharmGKB, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Midazolam Approved, Illicit Pharma Enzyme, substrate 806
Phenobarbital Approved, Investigational Pharma Agonist, Enzyme, inducer 66
Thiamine Approved, Investigational, Vet_approved Nutra Enzyme, inducer 116,116
Docetaxel Approved, Investigational Pharma Microtubulin disassembly inhibitor, Tubulin and VEGF inhibitor, Taxanes 2040
Thalidomide Approved, Investigational, Withdrawn Pharma Immunomodulatory agent,sedative drug,angiogenesis inhibitor, Immunomodulatory agents, TNF-alpha synthesis inhibitor 1195

(26) Additional Compounds for CYP4B1 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
11,12,15-THETA
  • 11,12,15-Trihydroxyicosatrienoic acid
  • (5Z,8Z,13E)-(15S)-11,12,15-Trihydroxyeicosa-5,8,12-trienoic acid
  • (5Z,8Z,13E)-(15S)-11,12,15-Trihydroxyicosa-5,8,12-trienoic acid
  • 11,12,15-Trihydroxyicosatrienoate
  • (5Z,8Z,13E)-(15S)-11,12,15-Trihydroxyeicosa-5,8,12-trienoate
11,12-Epoxyeicosatrienoic acid
  • (+/-)11(12)-eet
  • (+/-)11(12)-epetre
  • (+/-)11,12-epetre
  • (5Z,8Z,14Z)-11,12-Epoxyeicosa-5,8,14-trienoate
  • (5Z,8Z,14Z)-11,12-Epoxyeicosa-5,8,14-trienoic acid
81276-02-0
11,14,15-THETA
  • 11,14,15-Trihydroxyicosatrienoic acid
  • (5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoic acid
  • (5Z,8Z,12E)-11,14,15-Trihydroxyicosa-5,8,12-trienoic acid
  • 11,14,15-Trihydroxyicosatrienoate
  • (5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoate
11H-14,15-EETA
  • 11-Hydroxy-14,15-eeta
  • 11-Hydroxy-14,15-epoxyeicosatrienoic acid
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyeicosa-5,8,12-trienoic acid
  • (5Z,8Z,12E)-14,15-Epoxy-11-hydroxyicosa-5,8,12-trienoic acid
  • 11-Hydroxy-14,15-epoxyeicosatrienoate
219535-29-2
12,13-EpOME
  • (9Z)-11-(3-Pentyloxiran-2-yl)undec-9-enoic acids
  • (9Z)-12,13-Epoxyoctadecenoic acid
  • 12(13)-EpOME
  • 12,13-cis-Epoxyoctadecenoic acid
  • 12,13-Epoxy-9(Z)-octadecenoic acid
genes like me logo Genes that share compounds with CYP4B1: view

Transcripts for CYP4B1 Gene

Unigene Clusters for CYP4B1 Gene

Cytochrome P450, family 4, subfamily B, polypeptide 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CYP4B1

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CYP4B1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c
SP1: - -
SP2: - - -
SP3: - -
SP4: - - -
SP5: - -
SP6:

Relevant External Links for CYP4B1 Gene

GeneLoc Exon Structure for
CYP4B1
ECgene alternative splicing isoforms for
CYP4B1

Expression for CYP4B1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CYP4B1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CYP4B1 Gene

This gene is overexpressed in Nerve - Tibial (x6.8), Lung (x5.2), Bladder (x4.8), Adipose - Visceral (Omentum) (x4.3), and Adipose - Subcutaneous (x4.2).

Protein differential expression in normal tissues from HIPED for CYP4B1 Gene

This gene is overexpressed in Nasal epithelium (68.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CYP4B1 Gene



Protein tissue co-expression partners for CYP4B1 Gene

NURSA nuclear receptor signaling pathways regulating expression of CYP4B1 Gene:

CYP4B1

SOURCE GeneReport for Unigene cluster for CYP4B1 Gene:

Hs.436317

mRNA Expression by UniProt/SwissProt for CYP4B1 Gene:

P13584-CP4B1_HUMAN
Tissue specificity: Detected in the liver and lung (at protein level).

Evidence on tissue expression from TISSUES for CYP4B1 Gene

  • Lung(4.8)
genes like me logo Genes that share expression patterns with CYP4B1: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CYP4B1 Gene

Orthologs for CYP4B1 Gene

This gene was present in the common ancestor of animals.

Orthologs for CYP4B1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC456557 33
  • 99.4 (n)
CYP4B1 34
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CYP4B1 34 33
  • 87.28 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cyp4b1 33
  • 86.48 (n)
mouse
(Mus musculus)
Mammalia Cyp4b1 16 34 33
  • 86.14 (n)
cow
(Bos Taurus)
Mammalia CYP4B1 34 33
  • 84.67 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CYP4B1 34
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CYP4B1 34
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC771974 33
  • 65.17 (n)
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 54 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 52 (a)
ManyToMany
-- 34
  • 51 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487918 33
  • 60.61 (n)
zebrafish
(Danio rerio)
Actinopterygii cyp4t8 33
  • 57.89 (n)
fruit fly
(Drosophila melanogaster)
Insecta Cyp4d2 35
  • 37 (a)
Cyp4d14 35
  • 35 (a)
Cyp4g15 35
  • 35 (a)
Cyp4d8 35
  • 35 (a)
Cyp4s3 35
  • 34 (a)
Cyp4ae1 35
  • 34 (a)
Cyp4d1 35
  • 33 (a)
Cyp4c3 35
  • 33 (a)
Cyp4d20 35
  • 32 (a)
Cyp4p2 35
  • 30 (a)
Cyp4p1 35
  • 30 (a)
Cyp4e2 35
  • 30 (a)
Cyp4ac1 35
  • 30 (a)
Cyp311a1 35
  • 30 (a)
Cyp4e1 35
  • 29 (a)
Cyp4p3 35
  • 29 (a)
Cyp4g1 35
  • 29 (a)
Cyp4e3 35
  • 28 (a)
Cyp312a1 35
  • 28 (a)
Cyp4ac2 35
  • 28 (a)
Cyp4aa1 35
  • 27 (a)
Cyp4ad1 35
  • 27 (a)
Cyp313a1 35
  • 26 (a)
Cyp313b1 35
  • 24 (a)
worm
(Caenorhabditis elegans)
Secernentea F01D5.9 35
  • 36 (a)
Y38C9B.1 35
  • 34 (a)
Y80D3A.5 35
  • 32 (a)
F28G4.1 35
  • 32 (a)
Y5H2B.5 35
  • 32 (a)
Y17G9B.3 35
  • 32 (a)
B0331.1 35
  • 31 (a)
C26F1.2 35
  • 29 (a)
Species where no ortholog for CYP4B1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CYP4B1 Gene

ENSEMBL:
Gene Tree for CYP4B1 (if available)
TreeFam:
Gene Tree for CYP4B1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CYP4B1: view image

Paralogs for CYP4B1 Gene

(17) SIMAP similar genes for CYP4B1 Gene using alignment to 9 proteins:

  • CP4B1_HUMAN
  • E7EME6_HUMAN
  • E9PL36_HUMAN
  • E9PML0_HUMAN
  • F5H1Q8_HUMAN
  • F5H5Q6_HUMAN
  • F5H6F1_HUMAN
  • Q8IZB0_HUMAN
  • Q8WWV1_HUMAN

Pseudogenes.org Pseudogenes for CYP4B1 Gene

genes like me logo Genes that share paralogs with CYP4B1: view

Variants for CYP4B1 Gene

Sequence variations from dbSNP and Humsavar for CYP4B1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs3215983 benign, not specified 46,815,075(+) AT/ coding_sequence_variant, frameshift, non_coding_transcript_variant, splice_acceptor_variant
rs1000057154 -- 46,799,973(+) C/A genic_upstream_transcript_variant, intron_variant
rs1000095727 -- 46,797,239(+) C/A upstream_transcript_variant
rs1000166089 -- 46,809,430(+) G/C genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000173695 -- 46,809,726(+) T/G genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CYP4B1 Gene

Variant ID Type Subtype PubMed ID
dgv160n100 CNV gain 25217958
esv3585938 CNV gain 21293372
esv3585939 CNV gain 21293372
esv3585940 CNV loss 21293372
nsv1010063 CNV gain 25217958
nsv1011086 CNV gain 25217958
nsv546165 CNV loss 21841781

Variation tolerance for CYP4B1 Gene

Residual Variation Intolerance Score: 98.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 21.42; 99.28% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CYP4B1 Gene

Human Gene Mutation Database (HGMD)
CYP4B1
The Human Cytochrome P450 Allele Nomenclature Database
CYP4B1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CYP4B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYP4B1 Gene

Disorders for CYP4B1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CYP4B1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
bladder cancer
  • bladder cancer, somatic
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CYP4B1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CYP4B1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CYP4B1 Gene

Publications for CYP4B1 Gene

  1. Genetic polymorphism of the human cytochrome P450 CYP4B1: evidence for a non-functional allelic variant. (PMID: 12142726) Lo-Guidice JM … Broly F (Pharmacogenetics 2002) 3 4 22 44 58
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
  4. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PMID: 19343046) Saito A … Kamatani N (Journal of human genetics 2009) 3 44 58
  5. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PMID: 19898482) Ross CJ … CPNDS Consortium (Nature genetics 2009) 3 44 58

Products for CYP4B1 Gene

Sources for CYP4B1 Gene

Content
Loading form....