Aliases for USPL1 Gene
External Ids for USPL1 Gene
Previous HGNC Symbols for USPL1 Gene
Previous GeneCards Identifiers for USPL1 Gene
GeneCards Summary for USPL1 Gene
USPL1 (Ubiquitin Specific Peptidase Like 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ubiquitin binding and SUMO-specific isopeptidase activity.
UniProtKB/Swiss-Prot for USPL1 Gene
SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms (PubMed:22878415). Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (PubMed:24413172). Is a component of complexes that can bind to U snRNA genes (PubMed:24413172).