Aliases for IQSEC1 Gene
External Ids for IQSEC1 Gene
Previous GeneCards Identifiers for IQSEC1 Gene
GeneCards Summary for IQSEC1 Gene
IQSEC1 (IQ Motif And Sec7 Domain 1) is a Protein Coding gene. Among its related pathways are EGF/EGFR Signaling Pathway and Arf6 signaling events. Gene Ontology (GO) annotations related to this gene include lipid binding and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is IQSEC2.
UniProtKB/Swiss-Prot for IQSEC1 Gene
Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.