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Aliases for CKAP5 Gene

Aliases for CKAP5 Gene

  • Cytoskeleton Associated Protein 5 2 3 5
  • Colonic And Hepatic Tumor Overexpressed Gene Protein 3 4
  • Ch-TOG 3 4
  • Colonic And Hepatic Tumor Over-Expressed Gene Protein 3
  • Cytoskeleton-Associated Protein 5 3
  • KIAA0097 4
  • CHTOG 3
  • MSPS 3
  • TOGp 3
  • TOG 3

External Ids for CKAP5 Gene

Previous GeneCards Identifiers for CKAP5 Gene

  • GC11M046722
  • GC11M046470
  • GC11M046815
  • GC11M048068
  • GC11M048794
  • GC11M049892
  • GC11M047086
  • GC11M047930
  • GC11M050784
  • GC11M051579
  • GC11M052241
  • GC11M052901
  • GC11M053569
  • GC11M054235

Summaries for CKAP5 Gene

Entrez Gene Summary for CKAP5 Gene

  • This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

GeneCards Summary for CKAP5 Gene

CKAP5 (Cytoskeleton Associated Protein 5) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Organelle biogenesis and maintenance. Gene Ontology (GO) annotations related to this gene include binding and endonuclease activity.

UniProtKB/Swiss-Prot for CKAP5 Gene

  • Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448).

Gene Wiki entry for CKAP5 Gene

Additional gene information for CKAP5 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CKAP5 Gene

Genomics for CKAP5 Gene

GeneHancer (GH) Regulatory Elements for CKAP5 Gene

Promoters and enhancers for CKAP5 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J046844 Promoter/Enhancer 1.5 Ensembl ENCODE 650.7 +0.3 339 2.3 SMAD1 ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B ZNF207 FOS SP3 CKAP5 LRP4-AS1 ZNF408 FNBP4 ENSG00000270060 DDB2 AMBRA1 ENSG00000200090 F2 KBTBD4
GH11J046821 Promoter 0.7 EPDnew 650.3 +25.0 25009 0.1 RFX1 MYNN CKAP5 C11orf49 PIR53264
GH11J046770 Promoter 0.5 EPDnew 650.2 +76.0 76025 0.1 GC11M056217 CKAP5 F2 ZNF408 ARHGAP1 PIR53264
GH11J046647 Enhancer 1 Ensembl ENCODE dbSUPER 10.3 +197.1 197072 2.8 NFIA RXRA JUN RAD21 ATF2 NR2F2 SP1 JUND POLR2A ZBTB48 GC11M055307 ATG13 ARHGAP1 ZNF408 HARBI1 F2 AMBRA1 CHRM4 SNORD67 CKAP5
GH11J046710 Enhancer 0.9 Ensembl ENCODE dbSUPER 10.6 +135.0 135045 1.9 SP1 RXRA MAX HNF4A GABPA YY1 NR2F2 SNORD67 CKAP5 HARBI1 ATG13 C11orf49 MYBPC3 F2 ZNF408
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CKAP5 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CKAP5 gene promoter:
  • Lmo2
  • NF-1
  • E2F-1
  • E2F
  • HEN1
  • Pax-4a
  • Egr-2
  • AML1a
  • Zic3
  • CUTL1

Genomic Locations for CKAP5 Gene

Genomic Locations for CKAP5 Gene
chr11:46,743,048-46,846,308
(GRCh38/hg38)
Size:
103,261 bases
Orientation:
Minus strand
chr11:46,764,598-46,867,847
(GRCh37/hg19)
Size:
103,250 bases
Orientation:
Minus strand

Genomic View for CKAP5 Gene

Genes around CKAP5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CKAP5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CKAP5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CKAP5 Gene

Proteins for CKAP5 Gene

  • Protein details for CKAP5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14008-CKAP5_HUMAN
    Recommended name:
    Cytoskeleton-associated protein 5
    Protein Accession:
    Q14008
    Secondary Accessions:
    • Q05D70
    • Q0VAX7
    • Q0VAX8
    • Q14668
    • Q2TA89
    • Q6NSH4

    Protein attributes for CKAP5 Gene

    Size:
    2032 amino acids
    Molecular mass:
    225495 Da
    Quaternary structure:
    • Interacts with TACC1 (PubMed:11903063). Interacts with SLAIN2 and SLAIN1 (PubMed:21646404). Interacts with HNRNPA2B1 (PubMed:15703215). Interacts with TACC3 independently of clathrin (PubMed:25596274). Interacts with TACC3 and clathrin forming the TACC3/ch-TOG/clathrin complex located at spindle inter-microtubules bridges (PubMed:21297582, PubMed:23532825). Interacts with NDC80; indicative for an association with the NDC80 complex (PubMed:27156448).
    SequenceCaution:
    • Sequence=AAH17856.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAH70136.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAI11044.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAI20871.1; Type=Frameshift; Positions=18; Evidence={ECO:0000305}; Sequence=BAA07892.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for CKAP5 Gene

    Alternative splice isoforms for CKAP5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CKAP5 Gene

Post-translational modifications for CKAP5 Gene

  • Ubiquitination at posLast=19811981, Lys1774, posLast=15231523, posLast=754754, and posLast=4848
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CKAP5 Gene

Domains & Families for CKAP5 Gene

Gene Families for CKAP5 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for CKAP5 Gene

Suggested Antigen Peptide Sequences for CKAP5 Gene

Graphical View of Domain Structure for InterPro Entry

Q14008

UniProtKB/Swiss-Prot:

CKAP5_HUMAN :
  • The TOG (tumor overexpressed gene) domains are arranged in a N-terminal pentameric array with each domain composed of six (for the most part non-canonical) HEAT repeats forming a oblong paddle-like structure. Intra-HEAT loops are positioned along a face of the TOG domain and bind to a single alpha/beta-tubulin heterodimer. The TOG domains in the array seem to be structurally and functionally polarized. Differential functions may range from microtubule (MT) lattice binding and/or free tubulin heterodimer binding to potentiating stable incorporation of tubulin into the MT lattice.
  • Belongs to the TOG/XMAP215 family.
Domain:
  • The TOG (tumor overexpressed gene) domains are arranged in a N-terminal pentameric array with each domain composed of six (for the most part non-canonical) HEAT repeats forming a oblong paddle-like structure. Intra-HEAT loops are positioned along a face of the TOG domain and bind to a single alpha/beta-tubulin heterodimer. The TOG domains in the array seem to be structurally and functionally polarized. Differential functions may range from microtubule (MT) lattice binding and/or free tubulin heterodimer binding to potentiating stable incorporation of tubulin into the MT lattice.
Family:
  • Belongs to the TOG/XMAP215 family.
genes like me logo Genes that share domains with CKAP5: view

Function for CKAP5 Gene

Molecular function for CKAP5 Gene

UniProtKB/Swiss-Prot Function:
Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448).

Phenotypes From GWAS Catalog for CKAP5 Gene

Gene Ontology (GO) - Molecular Function for CKAP5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding IEA --
GO:0005515 protein binding IPI 11903063
GO:0045296 cadherin binding IDA 25468996
GO:0051010 microtubule plus-end binding IBA --
genes like me logo Genes that share ontologies with CKAP5: view
genes like me logo Genes that share phenotypes with CKAP5: view

Animal Models for CKAP5 Gene

MGI Knock Outs for CKAP5:

Animal Model Products

Clone Products

  • Addgene plasmids for CKAP5

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CKAP5 Gene

Localization for CKAP5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CKAP5 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Detected on centrosomes and kinetochores during interphase and mitosis independently from TACC3 and clathrin. Located to spindle poles and microtubules during mitosis. In complex with TACC3 localized to microtubule plus-ends in mitosis and interphase. In complex with TACC3 and clathrin localized to inter-microtubule bridges in mitotic spindles. Accumulation sites at microtubule plus ends protruded approximately 100 nm from MAPRE1/EB1 sites in interphase cells. {ECO:0000269 PubMed:21646404, ECO:0000269 PubMed:23251535, ECO:0000269 PubMed:25596274}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CKAP5 gene
Compartment Confidence
cytoskeleton 5
cytosol 5
plasma membrane 4
nucleus 2
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (3)
  • Nucleoli (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CKAP5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000775 chromosome, centromeric region IEA --
GO:0000776 kinetochore IDA,IEA 25596274
GO:0000777 condensed chromosome kinetochore IEA --
GO:0000922 spindle pole IEA,IDA 21646404
GO:0000930 colocalizes_with gamma-tubulin complex IDA 14718566
genes like me logo Genes that share ontologies with CKAP5: view

Pathways & Interactions for CKAP5 Gene

genes like me logo Genes that share pathways with CKAP5: view

Pathways by source for CKAP5 Gene

2 Cell Signaling Technology pathways for CKAP5 Gene

Gene Ontology (GO) - Biological Process for CKAP5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000086 G2/M transition of mitotic cell cycle TAS --
GO:0007019 microtubule depolymerization TAS 26323690
GO:0007049 cell cycle IEA --
GO:0007051 spindle organization IMP 14718566
GO:0007062 sister chromatid cohesion TAS --
genes like me logo Genes that share ontologies with CKAP5: view

No data available for SIGNOR curated interactions for CKAP5 Gene

Drugs & Compounds for CKAP5 Gene

(2) Drugs for CKAP5 Gene - From:

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
10-DAB (10-Deacetylbaccatin) Pharma Precursor of antitumor compound Palitaxel and Docetaxel 0
ABT-751 (E7010) Pharma Inhibitor of microtubule polymerization,antimitotic 0
genes like me logo Genes that share compounds with CKAP5: view

Transcripts for CKAP5 Gene

mRNA/cDNA for CKAP5 Gene

Unigene Clusters for CKAP5 Gene

Cytoskeleton associated protein 5:
Representative Sequences:

Clone Products

  • Addgene plasmids for CKAP5

Alternative Splicing Database (ASD) splice patterns (SP) for CKAP5 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22 ^ 23a · 23b ^ 24a ·
SP1:
SP2:
SP3: -
SP4:
SP5: -
SP6:
SP7:
SP8:

ExUns: 24b ^ 25 ^ 26a · 26b ^ 27 ^ 28 ^ 29 ^ 30a · 30b ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40 ^ 41
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8: -

Relevant External Links for CKAP5 Gene

GeneLoc Exon Structure for
CKAP5
ECgene alternative splicing isoforms for
CKAP5

Expression for CKAP5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CKAP5 Gene

Protein differential expression in normal tissues from HIPED for CKAP5 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (15.7) and Fetal Brain (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CKAP5 Gene



Protein tissue co-expression partners for CKAP5 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CKAP5 Gene:

CKAP5

SOURCE GeneReport for Unigene cluster for CKAP5 Gene:

Hs.201253

mRNA Expression by UniProt/SwissProt for CKAP5 Gene:

Q14008-CKAP5_HUMAN
Tissue specificity: Overexpressed in hepatomas and colonic tumors. Also expressed in skeletal muscle, brain, heart, placenta, lung, liver, kidney and pancreas. Expression is elevated in the brain; highly expressed in the Purkinje cell bodies of the cerebellum.

Evidence on tissue expression from TISSUES for CKAP5 Gene

  • Nervous system(4.5)
  • Liver(4.4)
  • Bone marrow(4.2)
  • Intestine(2.4)
  • Heart(2.2)
  • Lung(2.1)
  • Adrenal gland(2)
  • Gall bladder(2)
  • Kidney(2)
  • Skin(2)
  • Stomach(2)
  • Thyroid gland(2)
genes like me logo Genes that share expression patterns with CKAP5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CKAP5 Gene

Orthologs for CKAP5 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CKAP5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CKAP5 34 33
  • 99.67 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CKAP5 34
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CKAP5 34 33
  • 92.86 (n)
OneToOne
cow
(Bos Taurus)
Mammalia CKAP5 34 33
  • 92.31 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Ckap5 16 34 33
  • 90.52 (n)
rat
(Rattus norvegicus)
Mammalia Ckap5 33
  • 90.37 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia CKAP5 34
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves CKAP5 34 33
  • 80.19 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CKAP5 34
  • 87 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ckap5 33
  • 73.85 (n)
Str.3305 33
African clawed frog
(Xenopus laevis)
Amphibia LOC398198 33
zebrafish
(Danio rerio)
Actinopterygii ckap5 34 33
  • 70.81 (n)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta msps 34 33
  • 50.53 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011162 33
  • 50.43 (n)
worm
(Caenorhabditis elegans)
Secernentea T08D2.8 34
  • 30 (a)
OneToMany
zyg-9 34
  • 26 (a)
OneToMany
F54A3.2 34
  • 24 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes STU2 36 34
  • 25 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons MOR1 33
  • 45.42 (n)
rice
(Oryza sativa)
Liliopsida Os01g0816400 33
  • 44.79 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2441 34
  • 44 (a)
OneToOne
Species where no ortholog for CKAP5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CKAP5 Gene

ENSEMBL:
Gene Tree for CKAP5 (if available)
TreeFam:
Gene Tree for CKAP5 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CKAP5: view image

Paralogs for CKAP5 Gene

No data available for Paralogs for CKAP5 Gene

Variants for CKAP5 Gene

Sequence variations from dbSNP and Humsavar for CKAP5 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs193921076 uncertain-significance, Malignant tumor of prostate 46,809,784(-) T/C/G coding_sequence_variant, missense_variant
rs1000040605 -- 46,764,895(-) T/C intron_variant
rs1000049092 -- 46,818,318(-) T/C coding_sequence_variant, synonymous_variant
rs1000096481 -- 46,826,685(-) A/G intron_variant
rs1000102727 -- 46,790,920(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CKAP5 Gene

Variant ID Type Subtype PubMed ID
esv3547703 CNV deletion 23714750
nsv1122612 CNV deletion 24896259
nsv1138017 CNV deletion 24896259
nsv472167 CNV novel sequence insertion 20440878

Variation tolerance for CKAP5 Gene

Residual Variation Intolerance Score: 1.02% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.80; 47.52% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CKAP5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CKAP5

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CKAP5 Gene

Disorders for CKAP5 Gene

Additional Disease Information for CKAP5

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for CKAP5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CKAP5 Gene

Publications for CKAP5 Gene

  1. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 7788527) Nagase T … Kotani H (DNA research : an international journal for rapid publication of reports on genes and genomes 1995) 2 3 4 58
  2. Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors. (PMID: 8536682) Charrasse S … Larroque C (European journal of biochemistry 1995) 2 3 4 58
  3. A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments. (PMID: 27156448) Miller MP … Biggins S (Cell 2016) 3 4 58
  4. TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation. (PMID: 25596274) Gutiérrez-Caballero C … Royle SJ (Biology open 2015) 3 4 58
  5. Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells. (PMID: 23251535) Nakamura S … Mimori-Kiyosue Y (PloS one 2012) 3 4 58

Products for CKAP5 Gene

Sources for CKAP5 Gene

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