Aliases for IFT20 Gene
External Ids for IFT20 Gene
Previous GeneCards Identifiers for IFT20 Gene
This gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.[provided by RefSeq, Jun 2012]
GeneCards Summary for IFT20 Gene
IFT20 (Intraflagellar Transport 20) is a Protein Coding gene. Diseases associated with IFT20 include Retinitis Pigmentosa. Among its related pathways are Organelle biogenesis and maintenance and Intraflagellar transport. Gene Ontology (GO) annotations related to this gene include opsin binding.
UniProtKB/Swiss-Prot for IFT20 Gene
Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.