Aliases for SLC25A21 Gene
External Ids for SLC25A21 Gene
Previous GeneCards Identifiers for SLC25A21 Gene
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]
GeneCards Summary for SLC25A21 Gene
SLC25A21 (Solute Carrier Family 25 Member 21) is a Protein Coding gene. Diseases associated with SLC25A21 include Tooth Agenesis. Among its related pathways are Metabolism and Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism.
UniProtKB/Swiss-Prot for SLC25A21 Gene
Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.