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Aliases for RUNX3 Gene

Aliases for RUNX3 Gene

  • Runt Related Transcription Factor 3 2 3 5
  • Polyomavirus Enhancer-Binding Protein 2 Alpha C Subunit 3 4
  • SL3/AKV Core-Binding Factor Alpha C Subunit 3 4
  • SL3-3 Enhancer Factor 1 Alpha C Subunit 3 4
  • Core-Binding Factor Subunit Alpha-3 3 4
  • Runt-Related Transcription Factor 3 2 3
  • Acute Myeloid Leukemia 2 Protein 3 4
  • Oncogene AML-2 3 4
  • CBF-Alpha-3 3 4
  • CBFA3 3 4
  • AML2 3 4
  • Core-Binding Factor, Runt Domain, Alpha Subunit 3 3
  • Acute Myeloid Leukemia Gene 2 3
  • Transcription Factor AML2 3
  • PEBP2 Alpha C 3
  • PEBP2-Alpha C 4
  • PEA2 Alpha C 3
  • PEA2-Alpha C 4
  • PEBP2aC 3
  • PEBP2A3 4

External Ids for RUNX3 Gene

Previous HGNC Symbols for RUNX3 Gene

  • CBFA3

Previous GeneCards Identifiers for RUNX3 Gene

  • GC01M024749
  • GC01M024294
  • GC01M024205
  • GC01M024577
  • GC01M024971
  • GC01M025098
  • GC01M025226
  • GC01M023479

Summaries for RUNX3 Gene

Entrez Gene Summary for RUNX3 Gene

  • This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

GeneCards Summary for RUNX3 Gene

RUNX3 (Runt Related Transcription Factor 3) is a Protein Coding gene. Diseases associated with RUNX3 include Testicular Yolk Sac Tumor and Cleidocranial Dysplasia. Among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Wnt / Hedgehog / Notch. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is RUNX2.

UniProtKB/Swiss-Prot for RUNX3 Gene

  • Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5-TGTGGT-3, or very rarely, 5-TGCGGT-3, within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters (By similarity). May be involved in the control of cellular proliferation and/or differentiation. In association with ZFHX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712). CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development. They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation. CBF complexes binding to the transcriptional silencer is essential for recruitment of nuclear protein complexes that catalyze epigenetic modifications to establish epigenetic ZBTB7B silencing (By similarity).

Gene Wiki entry for RUNX3 Gene

Additional gene information for RUNX3 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RUNX3 Gene

Genomics for RUNX3 Gene

GeneHancer (GH) Regulatory Elements for RUNX3 Gene

Promoters and enhancers for RUNX3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J024908 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 688.9 +45.4 45406 22.8 HDGF PKNOX1 FOXA2 SMAD1 MLX ARNT ARID4B NEUROD1 SIN3A FEZF1 RUNX3 MIR6731 RCAN3 ENSG00000231953 RNU6-1208P RSRP1 ENSG00000225643 ENSG00000261349 SRRM1 SYF2
GH01J024961 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 652.9 +0.3 336 5.7 HDGF PKNOX1 ATF1 SMAD1 YBX1 IRF4 GLIS2 ZNF207 ZNF143 FOS RUNX3 SELENON RSRP1 SYF2 GC01M024954 GC01M024956 GC01M024930 GC01M024955 PIR43315 LOC105376878
GH01J025020 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 21.8 -57.5 -57536 4.9 HDGF PKNOX1 SMAD1 ZFP64 YBX1 IRF4 GLIS2 ARID2 ZNF207 ZNF143 MIR4425 RUNX3 LOC105376878 RSRP1 SYF2 SRRM1 GC01M024955
GH01J025030 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 17.3 -68.4 -68401 6.2 HDGF PKNOX1 SMAD1 FEZF1 YBX1 GLI4 IRF4 ZNF207 ATF7 RUNX3 SRRM1 SYF2 MAN1C1 RUNX3 ENSG00000261025 ENSG00000231953 ENSG00000207302 RPL39P7 LOC105376878 ENSG00000261349
GH01J023975 Promoter/Enhancer 2.9 UCNEbase EPDnew Ensembl ENCODE dbSUPER 9.9 +986.3 986320 6.4 CLOCK MLX DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC SRSF10 ELOA SRRM1 LINC01355 KDM1A RPL11 ZNF436-AS1 PNRC2 CNR2 RUNX3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RUNX3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RUNX3 gene promoter:
  • STAT3
  • p300
  • STAT2
  • STAT1beta
  • STAT1alpha
  • STAT1

Genomic Locations for RUNX3 Gene

Genomic Locations for RUNX3 Gene
chr1:24,899,511-24,965,157
(GRCh38/hg38)
Size:
65,647 bases
Orientation:
Minus strand
chr1:25,226,002-25,291,612
(GRCh37/hg19)
Size:
65,611 bases
Orientation:
Minus strand

Genomic View for RUNX3 Gene

Genes around RUNX3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RUNX3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RUNX3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RUNX3 Gene

Proteins for RUNX3 Gene

  • Protein details for RUNX3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13761-RUNX3_HUMAN
    Recommended name:
    Runt-related transcription factor 3
    Protein Accession:
    Q13761
    Secondary Accessions:
    • B1AJV5
    • Q12969
    • Q13760

    Protein attributes for RUNX3 Gene

    Size:
    415 amino acids
    Molecular mass:
    44356 Da
    Quaternary structure:
    • Heterodimer with CBFB. RUNX3 binds DNA as a monomer and through the Runt domain. DNA-binding is increased by heterodimerization (By similarity). Interacts with TLE1 and SUV39H1 (PubMed:9751710 and PubMed:16652147). The tyrosine phosphorylated form (via runt domain) interacts with SRC (via protein kinase domain)(PubMed:20100835). Interacts with FYN and LCK (PubMed:20100835). Interacts with FOXP3 (PubMed:17377532). Interacts with ZFHX3 (PubMed:20599712). Interacts with TBX21 (By similarity).

    Three dimensional structures from OCA and Proteopedia for RUNX3 Gene

    Alternative splice isoforms for RUNX3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RUNX3 Gene

Post-translational modifications for RUNX3 Gene

  • Phosphorylated on tyrosine residues by SRC. Phosphorylated by LCK and FYN.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RUNX3 Gene

No data available for DME Specific Peptides for RUNX3 Gene

Domains & Families for RUNX3 Gene

Gene Families for RUNX3 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Graphical View of Domain Structure for InterPro Entry

Q13761

UniProtKB/Swiss-Prot:

RUNX3_HUMAN :
  • A proline/serine/threonine rich region at the C-terminus is necessary for transcriptional activation of target genes.
Domain:
  • A proline/serine/threonine rich region at the C-terminus is necessary for transcriptional activation of target genes.
genes like me logo Genes that share domains with RUNX3: view

Function for RUNX3 Gene

Molecular function for RUNX3 Gene

UniProtKB/Swiss-Prot Function:
Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5-TGTGGT-3, or very rarely, 5-TGCGGT-3, within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters (By similarity). May be involved in the control of cellular proliferation and/or differentiation. In association with ZFHX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712). CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development. They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation. CBF complexes binding to the transcriptional silencer is essential for recruitment of nuclear protein complexes that catalyze epigenetic modifications to establish epigenetic ZBTB7B silencing (By similarity).
GENATLAS Biochemistry:
Drosophila Runt pair rule-related transcription factor 3,expressed in various lymphoid and myeloid cells,involved in hematopoiesis and osteogenesis

Phenotypes From GWAS Catalog for RUNX3 Gene

Gene Ontology (GO) - Molecular Function for RUNX3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding ISS --
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS,ISS 19274049
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity TAS 7607690
GO:0005515 protein binding IPI 9751710
genes like me logo Genes that share ontologies with RUNX3: view
genes like me logo Genes that share phenotypes with RUNX3: view

Animal Models for RUNX3 Gene

MGI Knock Outs for RUNX3:

Animal Model Products

miRNA for RUNX3 Gene

miRTarBase miRNAs that target RUNX3

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RUNX3 Gene

Localization for RUNX3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RUNX3 Gene

Nucleus. Cytoplasm. Note=The tyrosine phosphorylated form localizes to the cytoplasm. Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. {ECO:0000269 PubMed:20599712}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RUNX3 gene
Compartment Confidence
nucleus 5
cytosol 5
extracellular 2
golgi apparatus 2
plasma membrane 1
cytoskeleton 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleus (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RUNX3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin ISS --
GO:0005634 nucleus IDA 20100835
GO:0005654 nucleoplasm TAS --
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IDA,IEA 20100835
genes like me logo Genes that share ontologies with RUNX3: view

Pathways & Interactions for RUNX3 Gene

genes like me logo Genes that share pathways with RUNX3: view

Pathways by source for RUNX3 Gene

SIGNOR curated interactions for RUNX3 Gene

Inactivates:
Is inactivated by:

Gene Ontology (GO) - Biological Process for RUNX3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II ISS --
GO:0001503 ossification IBA --
GO:0002062 chondrocyte differentiation IBA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS 7622058
genes like me logo Genes that share ontologies with RUNX3: view

Drugs & Compounds for RUNX3 Gene

(1) Drugs for RUNX3 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(4) Additional Compounds for RUNX3 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with RUNX3: view

Transcripts for RUNX3 Gene

Unigene Clusters for RUNX3 Gene

Runt-related transcription factor 3:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RUNX3 Gene

No ASD Table

Relevant External Links for RUNX3 Gene

GeneLoc Exon Structure for
RUNX3
ECgene alternative splicing isoforms for
RUNX3

Expression for RUNX3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RUNX3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RUNX3 Gene

This gene is overexpressed in Whole Blood (x16.1) and Spleen (x4.8).

Protein differential expression in normal tissues from HIPED for RUNX3 Gene

This gene is overexpressed in NK cells (28.2), Peripheral blood mononuclear cells (15.7), CD8 Tcells (10.1), and CD4 Tcells (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RUNX3 Gene



Protein tissue co-expression partners for RUNX3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RUNX3 Gene:

RUNX3

SOURCE GeneReport for Unigene cluster for RUNX3 Gene:

Hs.170019

mRNA Expression by UniProt/SwissProt for RUNX3 Gene:

Q13761-RUNX3_HUMAN
Tissue specificity: Expressed in gastric cancer tissues (at protein level).

Evidence on tissue expression from TISSUES for RUNX3 Gene

  • Skin(4.3)
  • Blood(2.8)
  • Intestine(2.6)
  • Lymph node(2.6)
  • Stomach(2.5)
  • Bone marrow(2.4)
  • Spleen(2.1)
  • Lung(2)
genes like me logo Genes that share expression patterns with RUNX3: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for RUNX3 Gene

Orthologs for RUNX3 Gene

This gene was present in the common ancestor of animals.

Orthologs for RUNX3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RUNX3 34 33
  • 99.38 (n)
OneToOne
dog
(Canis familiaris)
Mammalia LOC487366 33
  • 92.12 (n)
RUNX3 34
  • 87 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RUNX3 34 33
  • 91.58 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Runx3 16 34 33
  • 89.18 (n)
rat
(Rattus norvegicus)
Mammalia Runx3 33
  • 88.67 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 88 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia RUNX3 34
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves RUNX3 34 33
  • 80.56 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RUNX3 34
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia runx3 33
  • 72.55 (n)
zebrafish
(Danio rerio)
Actinopterygii runx3 34 33
  • 68.02 (n)
OneToOne
-- 33
fruit fly
(Drosophila melanogaster)
Insecta CG1379 35
  • 73 (a)
CG15455 35
  • 67 (a)
run 34 35
  • 20 (a)
ManyToMany
RunxA 34
  • 18 (a)
ManyToMany
RunxB 34
  • 17 (a)
ManyToMany
lz 34 35
  • 14 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea rnt-1 34
  • 28 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 65 (a)
OneToMany
Species where no ortholog for RUNX3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RUNX3 Gene

ENSEMBL:
Gene Tree for RUNX3 (if available)
TreeFam:
Gene Tree for RUNX3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RUNX3: view image

Paralogs for RUNX3 Gene

Paralogs for RUNX3 Gene

(6) SIMAP similar genes for RUNX3 Gene using alignment to 2 proteins:

  • RUNX3_HUMAN
  • F5H4J4_HUMAN
genes like me logo Genes that share paralogs with RUNX3: view

Variants for RUNX3 Gene

Sequence variations from dbSNP and Humsavar for RUNX3 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000081063 -- 24,956,278(-) T/C genic_upstream_transcript_variant, intron_variant
rs1000100250 -- 24,918,414(-) C/G genic_downstream_transcript_variant, intron_variant
rs1000174179 -- 24,902,864(-) T/C genic_downstream_transcript_variant, intron_variant
rs1000295993 -- 24,945,474(-) C/T genic_upstream_transcript_variant, intron_variant
rs1000302882 -- 24,940,645(-) G/T genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for RUNX3 Gene

Variant ID Type Subtype PubMed ID
nsv1077252 CNV deletion 25765185
nsv1136070 CNV deletion 24896259
nsv508581 CNV deletion 20534489

Variation tolerance for RUNX3 Gene

Residual Variation Intolerance Score: 26.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.57; 12.28% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RUNX3 Gene

Human Gene Mutation Database (HGMD)
RUNX3
SNPedia medical, phenotypic, and genealogical associations of SNPs for
RUNX3

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RUNX3 Gene

Disorders for RUNX3 Gene

MalaCards: The human disease database

(8) MalaCards diseases for RUNX3 Gene - From: HGMD, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
testicular yolk sac tumor
  • yolk sac tumor
cleidocranial dysplasia
  • ccd
inflammatory bowel disease 7
  • ibd7
atrophic gastritis
  • gastric atrophy
gastric cancer
  • gastric cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
Search RUNX3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for RUNX3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with RUNX3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RUNX3 Gene

Publications for RUNX3 Gene

  1. Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm. (PMID: 20100835) Goh YM … Bae SC (The Journal of biological chemistry 2010) 3 4 22 58
  2. Chromatin immunoprecipitation and association study revealed a possible role of Runt-related transcription factor 3 in the ulcerative colitis of Chinese population. (PMID: 20392673) Guo C … Ding J (Clinical immunology (Orlando, Fla.) 2010) 3 22 44 58
  3. [The relationship between RUNX3 gene mutation and keloid]. (PMID: 18717361) Zhang G … Yu Q (Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 2008) 3 22 44 58
  4. Genetic variants in RUNX3 and risk of bladder cancer: a haplotype-based analysis. (PMID: 18684727) Zhang Z … Zhang Z (Carcinogenesis 2008) 3 22 44 58
  5. AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization. (PMID: 7835892) Levanon D … Groner Y (Genomics 1994) 2 3 4 58

Products for RUNX3 Gene

Sources for RUNX3 Gene

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