Aliases for ZMIZ2 Gene
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]
GeneCards Summary for ZMIZ2 Gene
ZMIZ2 (Zinc Finger MIZ-Type Containing 2) is a Protein Coding gene. Among its related pathways are Regulation of Androgen receptor activity. Gene Ontology (GO) annotations related to this gene include ligand-dependent nuclear receptor transcription coactivator activity. An important paralog of this gene is ZMIZ1.
UniProtKB/Swiss-Prot for ZMIZ2 Gene
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.