Aliases for FCRL4 Gene
External Ids for FCRL4 Gene
Previous GeneCards Identifiers for FCRL4 Gene
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]
GeneCards Summary for FCRL4 Gene
FCRL4 (Fc Receptor Like 4) is a Protein Coding gene. Among its related pathways are Microglia Activation During Neuroinflammation: Steady-State Microglia. An important paralog of this gene is FCRL5.
UniProtKB/Swiss-Prot for FCRL4 Gene
May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.