Aliases for ACOX3 Gene
External Ids for ACOX3 Gene
Previous GeneCards Identifiers for ACOX3 Gene
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACOX3 Gene
ACOX3 (Acyl-CoA Oxidase 3, Pristanoyl) is a Protein Coding gene. Among its related pathways are Peroxisomal lipid metabolism and Fatty acid elongation. Gene Ontology (GO) annotations related to this gene include receptor binding and oxidoreductase activity, acting on the CH-CH group of donors. An important paralog of this gene is ACOX1.
UniProtKB/Swiss-Prot for ACOX3 Gene
Oxidizes the CoA-esters of 2-methyl-branched fatty acids.