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Aliases for FAM192A Gene

Aliases for FAM192A Gene

  • Family With Sequence Similarity 192 Member A 2 3 5
  • NEFA-Interacting Nuclear Protein NIP30 3 4
  • C16orf94 3 4
  • NIP30 3 4
  • Family With Sequence Similarity 192, Member A 2
  • NEFA Interacting Nuclear Protein NIP30 2
  • Chromosome 16 Open Reading Frame 94 2
  • Protein FAM192A 3
  • CDA018 3
  • CDA10 3

External Ids for FAM192A Gene

Previous HGNC Symbols for FAM192A Gene

  • C16orf94

Previous GeneCards Identifiers for FAM192A Gene

  • GC16M055744
  • GC16M043056

Summaries for FAM192A Gene

GeneCards Summary for FAM192A Gene

FAM192A (Family With Sequence Similarity 192 Member A) is a Protein Coding gene.

Gene Wiki entry for FAM192A Gene

Additional gene information for FAM192A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM192A Gene

Genomics for FAM192A Gene

GeneHancer (GH) Regulatory Elements for FAM192A Gene

Promoters and enhancers for FAM192A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J057184 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 671.4 -0.6 -584 4.6 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B E2F8 RSPRY1 FAM192A NUP93 PLLP NUDT21 ARL2BP
GH16J057446 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 650.1 -261.1 -261110 2.4 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 POLR2B CBX5 CIAPIN1 COQ9 FAM192A LOC101927556 POLR2C RSPRY1 ADGRG5 GC16P057442
GH16J057173 Promoter 0.5 EPDnew 650.4 +12.4 12367 0.1 FAM192A NLRC5 RSPRY1 ENSG00000279019
GH16J057141 Enhancer 1.2 Ensembl ENCODE dbSUPER 27.3 +42.5 42476 5.1 HDAC1 ELF3 PKNOX1 RAD21 TCF12 GATA2 EGR1 SCRT2 ZFP91 EGR2 ENSG00000279803 ENSG00000279019 FAM192A PLLP RSPRY1 ARL2BP BBS2 CPNE2
GH16J057146 Enhancer 1 Ensembl ENCODE dbSUPER 31 +38.2 38207 3.5 CTCF STAT1 MAX STAT5A ZIC2 NR2F2 ETS1 POLR2A SCRT2 ZNF143 FAM192A PLLP CPNE2 RSPRY1 ENSG00000261114 ENSG00000279019
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM192A on UCSC Golden Path with GeneCards custom track

Genomic Locations for FAM192A Gene

Genomic Locations for FAM192A Gene
chr16:57,152,466-57,186,230
(GRCh38/hg38)
Size:
33,765 bases
Orientation:
Minus strand
chr16:57,186,378-57,220,028
(GRCh37/hg19)
Size:
33,651 bases
Orientation:
Minus strand

Genomic View for FAM192A Gene

Genes around FAM192A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM192A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM192A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM192A Gene

Proteins for FAM192A Gene

  • Protein details for FAM192A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZU8-F192A_HUMAN
    Recommended name:
    Protein FAM192A
    Protein Accession:
    Q9GZU8

    Protein attributes for FAM192A Gene

    Size:
    254 amino acids
    Molecular mass:
    28912 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM192A Gene

Post-translational modifications for FAM192A Gene

  • Ubiquitination at Lys151
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Abcam antibodies for FAM192A
  • Boster Bio Antibodies for FAM192A

No data available for DME Specific Peptides for FAM192A Gene

Domains & Families for FAM192A Gene

Gene Families for FAM192A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM192A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM192A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM192A: view

No data available for UniProtKB/Swiss-Prot for FAM192A Gene

Function for FAM192A Gene

Phenotypes From GWAS Catalog for FAM192A Gene

Gene Ontology (GO) - Molecular Function for FAM192A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM192A: view
genes like me logo Genes that share phenotypes with FAM192A: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM192A Gene

Localization for FAM192A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM192A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM192A gene
Compartment Confidence
nucleus 5
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Vesicles (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for FAM192A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with FAM192A: view

Pathways & Interactions for FAM192A Gene

SuperPathways for FAM192A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM192A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM192A Gene

Drugs & Compounds for FAM192A Gene

No Compound Related Data Available

Transcripts for FAM192A Gene

Unigene Clusters for FAM192A Gene

Family with sequence similarity 192, member A:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM192A Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14
SP1: - - - - -
SP2: - - - - -
SP3:
SP4: -
SP5: - -
SP6: -
SP7:

Relevant External Links for FAM192A Gene

GeneLoc Exon Structure for
FAM192A
ECgene alternative splicing isoforms for
FAM192A

Expression for FAM192A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM192A Gene

Protein differential expression in normal tissues from HIPED for FAM192A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (39.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FAM192A Gene



Protein tissue co-expression partners for FAM192A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM192A Gene:

FAM192A

SOURCE GeneReport for Unigene cluster for FAM192A Gene:

Hs.396740

Evidence on tissue expression from TISSUES for FAM192A Gene

  • Eye(4.3)
  • Intestine(4.3)
  • Lymph node(4.3)
  • Nervous system(4.3)
genes like me logo Genes that share expression patterns with FAM192A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM192A Gene

Orthologs for FAM192A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM192A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM192A 34 33
  • 99.48 (n)
OneToOne
cow
(Bos Taurus)
Mammalia NIP30 34
  • 96 (a)
OneToOne
FAM192A 33
  • 92.23 (n)
dog
(Canis familiaris)
Mammalia FAM192A 34 33
  • 91.6 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nip30 33
  • 88.8 (n)
mouse
(Mus musculus)
Mammalia Fam192a 16 34 33
  • 88.54 (n)
oppossum
(Monodelphis domestica)
Mammalia FAM192A 34
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM192A 34
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM192A 34 33
  • 77.03 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM192A 34
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam192a 33
  • 65.61 (n)
Str.11948 33
African clawed frog
(Xenopus laevis)
Amphibia nip30-prov 33
zebrafish
(Danio rerio)
Actinopterygii fam192a 34 33
  • 65.37 (n)
OneToOne
wufa02g12 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010768 33
  • 52 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG14480 34 33
  • 49.35 (n)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C25A1.1 34
  • 37 (a)
OneToOne
Species where no ortholog for FAM192A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM192A Gene

ENSEMBL:
Gene Tree for FAM192A (if available)
TreeFam:
Gene Tree for FAM192A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for FAM192A: view image

Paralogs for FAM192A Gene

(1) SIMAP similar genes for FAM192A Gene using alignment to 14 proteins:

  • F192A_HUMAN
  • H3BMX9_HUMAN
  • H3BN22_HUMAN
  • H3BNK9_HUMAN
  • H3BP64_HUMAN
  • H3BPF9_HUMAN
  • H3BPH9_HUMAN
  • H3BQQ6_HUMAN
  • H3BSF0_HUMAN
  • H3BSY6_HUMAN
  • H3BTI2_HUMAN
  • H3BTP8_HUMAN
  • H3BU93_HUMAN
  • H3BUL4_HUMAN

Pseudogenes.org Pseudogenes for FAM192A Gene

genes like me logo Genes that share paralogs with FAM192A: view

No data available for Paralogs for FAM192A Gene

Variants for FAM192A Gene

Sequence variations from dbSNP and Humsavar for FAM192A Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000049834 -- 57,181,256(-) T/C genic_upstream_transcript_variant, intron_variant
rs1000210351 -- 57,174,611(-) T/C genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000227907 -- 57,168,107(-) C/T intron_variant
rs1000256645 -- 57,186,918(-) C/G upstream_transcript_variant
rs1000342220 -- 57,168,373(-) C/T intron_variant

Variation tolerance for FAM192A Gene

Residual Variation Intolerance Score: 35.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.36; 7.95% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM192A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM192A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM192A Gene

Disorders for FAM192A Gene

Additional Disease Information for FAM192A

No disorders were found for FAM192A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM192A Gene

Publications for FAM192A Gene

  1. Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RING finger and SPRY domain containing 1 in skeletal muscle. (PMID: 26497270) Waddell DS … Eldredge JT (Gene 2016) 2 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons. (PMID: 26514267) Benleulmi-Chaachoua A … Jockers R (Journal of pineal research 2016) 3 58

Products for FAM192A Gene

Sources for FAM192A Gene

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