Aliases for XK Gene
External Ids for XK Gene
Previous HGNC Symbols for XK Gene
Previous GeneCards Identifiers for XK Gene
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]
GeneCards Summary for XK Gene
XK (X-Linked Kx Blood Group) is a Protein Coding gene. Diseases associated with XK include Mcleod Syndrome and Choreoacanthocytosis. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include transporter activity. An important paralog of this gene is XKRX.
UniProtKB/Swiss-Prot for XK Gene
May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.