Aliases for SSR2 Gene
External Ids for SSR2 Gene
Previous GeneCards Identifiers for SSR2 Gene
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008]
GeneCards Summary for SSR2 Gene
SSR2 (Signal Sequence Receptor Subunit 2) is a Protein Coding gene. Diseases associated with SSR2 include Synostoses, Tarsal, Carpal, And Digital and Ectopic Cushing Syndrome. Among its related pathways are Protein processing in endoplasmic reticulum and Metabolism of proteins.
UniProtKB/Swiss-Prot for SSR2 Gene
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.