Aliases for SNCG Gene
External Ids for SNCG Gene
Previous GeneCards Identifiers for SNCG Gene
This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]
GeneCards Summary for SNCG Gene
SNCG (Synuclein Gamma) is a Protein Coding gene. Diseases associated with SNCG include Synucleinopathy and Dementia, Lewy Body. Gene Ontology (GO) annotations related to this gene include beta-tubulin binding and alpha-tubulin binding. An important paralog of this gene is SNCA.
UniProtKB/Swiss-Prot for SNCG Gene
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).