Aliases for NEUROG2 Gene
External Ids for NEUROG2 Gene
Previous GeneCards Identifiers for NEUROG2 Gene
This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012]
GeneCards Summary for NEUROG2 Gene
NEUROG2 (Neurogenin 2) is a Protein Coding gene. Diseases associated with NEUROG2 include Partial Fetal Alcohol Syndrome. Among its related pathways are Dopaminergic Neurogenesis and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and E-box binding. An important paralog of this gene is NEUROG1.
UniProtKB/Swiss-Prot for NEUROG2 Gene
Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5-CANNTG-3).