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Aliases for ZNF471 Gene

Aliases for ZNF471 Gene

  • Zinc Finger Protein 471 2 3 3 5
  • EZFIT-Related Protein 1 3 4
  • ERP1 3 4
  • KIAA1396 4
  • Z1971 3

External Ids for ZNF471 Gene

Previous GeneCards Identifiers for ZNF471 Gene

  • GC19P061711
  • GC19P061610
  • GC19P057019
  • GC19P053329

Summaries for ZNF471 Gene

GeneCards Summary for ZNF471 Gene

ZNF471 (Zinc Finger Protein 471) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZFP28.

UniProtKB/Swiss-Prot for ZNF471 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF471 Gene

Additional gene information for ZNF471 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF471 Gene

Genomics for ZNF471 Gene

GeneHancer (GH) Regulatory Elements for ZNF471 Gene

Promoters and enhancers for ZNF471 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J056507 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE 663.5 +0.3 330 2.1 ZSCAN4 SIN3A YY1 ETS1 ZNF335 ZNF121 GLIS2 ZNF366 ZNF143 KLF7 ZNF471 LOC105372471 ZNF17 U2AF2 ZNF548 ZNF264 ENSG00000269696 ZNF667 ZNF543 ZNF304
GH19J056476 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 650.3 -30.2 -30212 3.1 ATF1 SIN3A YY1 ETS1 ZNF335 GLIS2 EGR1 ZNF143 KLF7 ZNF548 ZNF667-AS1 ZNF667 ZNF471 ZNF264 SSC5D U2AF2 ZNF543 ENSG00000267523 ZNF582-AS1 ZNF805
GH19J055519 Enhancer 1.4 FANTOM5 Ensembl ENCODE 87.4 -987.6 -987634 1 HDGF ATF1 ZNF493 ZNF133 YBX1 GLI4 ZNF416 ZNF548 FOS ATF7 U2AF2 ZNF471 FIZ1 ZNF582 ZNF581 ZNF580 SSC5D ENSG00000267523 NAT14 ZNF667
GH19J056403 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 46.9 -103.7 -103694 2 HDGF ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 ZNF416 ZNF207 ZNF582 ZNF582-AS1 ZFP28 ZNF470 ZNF471 FIZ1 ZNF264 ZNF460-AS1 ENSG00000269696 ZNF542P
GH19J056594 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 40 +87.6 87597 1.4 HDGF PKNOX1 ZNF133 ARID4B SIN3A FEZF1 YBX1 GLI4 ZNF48 YY1 ZNF71 U2AF2 ZNF264 ZNF17 ZNF543 ZNF773 ZNF549 ZNF550 ENSG00000269696 ENSG00000267523
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF471 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF471 gene promoter:
  • PPAR-gamma1
  • PPAR-gamma2
  • POU3F2
  • GCNF
  • GCNF-1
  • GCNF-2

Genomic Locations for ZNF471 Gene

Genomic Locations for ZNF471 Gene
22,379 bases
Plus strand
22,379 bases
Plus strand

Genomic View for ZNF471 Gene

Genes around ZNF471 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF471 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF471 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF471 Gene

Proteins for ZNF471 Gene

  • Protein details for ZNF471 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 471
    Protein Accession:
    Secondary Accessions:
    • B4DF32
    • O75260
    • Q08AD6
    • Q08AD7
    • Q8N3V1
    • Q9P2F1

    Protein attributes for ZNF471 Gene

    626 amino acids
    Molecular mass:
    73009 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC32422.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF471 Gene


neXtProt entry for ZNF471 Gene

Post-translational modifications for ZNF471 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF471 Gene

No data available for DME Specific Peptides for ZNF471 Gene

Domains & Families for ZNF471 Gene

Gene Families for ZNF471 Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF471 Gene

Suggested Antigen Peptide Sequences for ZNF471 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF471: view

Function for ZNF471 Gene

Molecular function for ZNF471 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF471 Gene

Gene Ontology (GO) - Molecular Function for ZNF471 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF471: view
genes like me logo Genes that share phenotypes with ZNF471: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF471 Gene

Localization for ZNF471 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF471 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF471 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF471 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with ZNF471: view

Pathways & Interactions for ZNF471 Gene

SuperPathways for ZNF471 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF471: view

Pathways by source for ZNF471 Gene

2 Reactome pathways for ZNF471 Gene

Gene Ontology (GO) - Biological Process for ZNF471 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA,IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF471: view

No data available for SIGNOR curated interactions for ZNF471 Gene

Drugs & Compounds for ZNF471 Gene

No Compound Related Data Available

Transcripts for ZNF471 Gene

mRNA/cDNA for ZNF471 Gene

Unigene Clusters for ZNF471 Gene

Zinc finger protein 471:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF471 Gene

No ASD Table

Relevant External Links for ZNF471 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF471 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF471 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF471 Gene

Protein tissue co-expression partners for ZNF471 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF471 Gene:


SOURCE GeneReport for Unigene cluster for ZNF471 Gene:


Evidence on tissue expression from TISSUES for ZNF471 Gene

  • Nervous system(4.2)
  • Muscle(4.1)
  • Pancreas(4.1)
genes like me logo Genes that share expression patterns with ZNF471: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF471 Gene

Orthologs for ZNF471 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF471 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF471 34 33
  • 99.36 (n)
(Mus musculus)
Mammalia Zfp78 16 33
  • 70.58 (n)
Zfp84 34
  • 45 (a)
(Canis familiaris)
Mammalia ZNF471 34
  • 66 (a)
Species where no ortholog for ZNF471 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF471 Gene

Gene Tree for ZNF471 (if available)
Gene Tree for ZNF471 (if available)
Evolutionary constrained regions (ECRs) for ZNF471: view image

Paralogs for ZNF471 Gene

(464) SIMAP similar genes for ZNF471 Gene using alignment to 3 proteins:

  • ZN471_HUMAN
  • B4DF32_HUMAN
genes like me logo Genes that share paralogs with ZNF471: view

Variants for ZNF471 Gene

Sequence variations from dbSNP and Humsavar for ZNF471 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
VAR_035583 A colorectal cancer sample p.Phe361Cys
rs1000124736 -- 56,508,616(+) C/T 5_prime_UTR_variant, intron_variant
rs1000129499 -- 56,527,727(+) T/A 3_prime_UTR_variant
rs1000183826 -- 56,527,541(+) C/G 3_prime_UTR_variant
rs1000185355 -- 56,522,255(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF471 Gene

Variant ID Type Subtype PubMed ID
dgv6591n54 CNV loss 21841781
esv3359099 CNV insertion 20981092
esv3371782 CNV insertion 20981092
nsv1055357 CNV gain 25217958
nsv580387 CNV loss 21841781

Variation tolerance for ZNF471 Gene

Residual Variation Intolerance Score: 77.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.42; 92.79% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF471 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF471 Gene

Disorders for ZNF471 Gene

Additional Disease Information for ZNF471

No disorders were found for ZNF471 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF471 Gene

Publications for ZNF471 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Gene promoter-associated CpG island hypermethylation in squamous cell carcinoma of the tongue. (PMID: 28255813) Bhat S … Satyamoorthy K (Virchows Archiv : an international journal of pathology 2017) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for ZNF471 Gene

Sources for ZNF471 Gene

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