Aliases for EAF2 Gene
External Ids for EAF2 Gene
Previous GeneCards Identifiers for EAF2 Gene
GeneCards Summary for EAF2 Gene
EAF2 (ELL Associated Factor 2) is a Protein Coding gene. Diseases associated with EAF2 include Eaf and Retinal Aplasia. Among its related pathways are Formation of HIV-1 elongation complex containing HIV-1 Tat and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA polymerase II regulatory region sequence-specific DNA binding and transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding. An important paralog of this gene is EAF1.
UniProtKB/Swiss-Prot for EAF2 Gene
Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.