Aliases for SEMA4C Gene
External Ids for SEMA4C Gene
Previous HGNC Symbols for SEMA4C Gene
Previous GeneCards Identifiers for SEMA4C Gene
GeneCards Summary for SEMA4C Gene
SEMA4C (Semaphorin 4C) is a Protein Coding gene. Diseases associated with SEMA4C include Retinitis Pigmentosa 33. Among its related pathways are Axon guidance. An important paralog of this gene is SEMA4G.
UniProtKB/Swiss-Prot for SEMA4C Gene
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at Tyr-1248. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.