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Aliases for RBM47 Gene

Aliases for RBM47 Gene

  • RNA Binding Motif Protein 47 2 3 5
  • RNA-Binding Motif Protein 47 4
  • RNA-Binding Protein 47 3
  • NET18 3

External Ids for RBM47 Gene

Previous GeneCards Identifiers for RBM47 Gene

  • GC04M040121
  • GC04M039747

Summaries for RBM47 Gene

GeneCards Summary for RBM47 Gene

RBM47 (RNA Binding Motif Protein 47) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is A1CF.

Additional gene information for RBM47 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM47 Gene

Genomics for RBM47 Gene

GeneHancer (GH) Regulatory Elements for RBM47 Gene

Promoters and enhancers for RBM47 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J040625 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 650.7 +1.9 1881 7.2 PKNOX1 SMAD1 SIN3A YY1 ETS1 GLIS2 ZNF207 FOS RUNX3 SP3 RBM47 UCHL1 MIR4802
GH04J040510 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 650.1 +116.9 116858 7.2 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF143 RBM47 PDS5A RNU7-74P MIR4802
GH04J040572 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 24.8 +54.3 54251 8.8 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 IRF4 YY1 ZNF207 RBM47 PDS5A N4BP2 CHRNA9 ENSG00000250906 RNU7-74P NSUN7 MIR4802
GH04J040721 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 25.2 -91.9 -91886 3 HDGF MEIS2 FOXA2 TEAD4 TAL1 ZBTB40 BATF CTBP1 NFATC1 ATF7 RBM47 ENSG00000250906 CHRNA9 RNU7-74P NSUN7 GC04P040643
GH04J040189 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 12.1 +430.7 430736 22 HDGF PKNOX1 FOXA2 SMAD1 ARNT SIN3A IRF4 YY1 POLR2B ZNF766 RHOH PDS5A N4BP2 RFC1 RBM47 LOC344967 ENSG00000250568 CHRNA9 ENSG00000250906 UGDH-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RBM47 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RBM47 gene promoter:
  • IRF-1
  • S8
  • Ik-2
  • NF-kappaB1
  • GATA-3
  • C/EBPalpha
  • NF-kappaB
  • NF-kappaB2
  • STAT5B
  • HOXA3

Genomic Locations for RBM47 Gene

Genomic Locations for RBM47 Gene
207,621 bases
Minus strand
207,621 bases
Minus strand

Genomic View for RBM47 Gene

Genes around RBM47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM47 Gene

Proteins for RBM47 Gene

  • Protein details for RBM47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding protein 47
    Protein Accession:
    Secondary Accessions:
    • A0PJK2
    • B5MED4
    • Q8NI52
    • Q8NI53
    • Q9NXG3

    Protein attributes for RBM47 Gene

    593 amino acids
    Molecular mass:
    64099 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAM21973.1; Type=Frameshift; Positions=561, 577; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for RBM47 Gene

    Alternative splice isoforms for RBM47 Gene


neXtProt entry for RBM47 Gene

Post-translational modifications for RBM47 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RBM47 Gene

Domains & Families for RBM47 Gene

Gene Families for RBM47 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the RRM RBM47 family.
  • Belongs to the RRM RBM47 family.
genes like me logo Genes that share domains with RBM47: view

Function for RBM47 Gene

Phenotypes From GWAS Catalog for RBM47 Gene

Gene Ontology (GO) - Molecular Function for RBM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IEA,HDA 22658674
genes like me logo Genes that share ontologies with RBM47: view
genes like me logo Genes that share phenotypes with RBM47: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM47 Gene

Localization for RBM47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBM47 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBM47 gene
Compartment Confidence
nucleus 5
cytosol 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoplasm (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RBM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with RBM47: view

Pathways & Interactions for RBM47 Gene

SuperPathways for RBM47 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002244 hematopoietic progenitor cell differentiation IEA --
GO:0016554 cytidine to uridine editing IEA --
genes like me logo Genes that share ontologies with RBM47: view

No data available for Pathways by source and SIGNOR curated interactions for RBM47 Gene

Drugs & Compounds for RBM47 Gene

No Compound Related Data Available

Transcripts for RBM47 Gene

Unigene Clusters for RBM47 Gene

RNA binding motif protein 47:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBM47 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9
SP1: - - - - -
SP2: -
SP3: - -
SP4: -
SP6: -

Relevant External Links for RBM47 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBM47 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RBM47 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RBM47 Gene

This gene is overexpressed in Colon - Transverse (x4.9), Adrenal Gland (x4.5), and Whole Blood (x4.0).

Protein differential expression in normal tissues from HIPED for RBM47 Gene

This gene is overexpressed in Cervix (17.2) and Salivary gland (10.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RBM47 Gene

Protein tissue co-expression partners for RBM47 Gene

NURSA nuclear receptor signaling pathways regulating expression of RBM47 Gene:


SOURCE GeneReport for Unigene cluster for RBM47 Gene:


Evidence on tissue expression from TISSUES for RBM47 Gene

  • Lung(4.4)
  • Nervous system(4.1)
  • Kidney(2.8)
genes like me logo Genes that share expression patterns with RBM47: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RBM47 Gene

Orthologs for RBM47 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM47 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RBM47 34 33
  • 99.44 (n)
(Bos Taurus)
Mammalia DKFZP686F02235 34
  • 98 (a)
RBM47 33
  • 92.02 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 92 (a)
-- 34
  • 82 (a)
-- 34
  • 82 (a)
(Canis familiaris)
Mammalia RBM47 34 33
  • 91.65 (n)
(Ornithorhynchus anatinus)
Mammalia RBM47 34
  • 89 (a)
(Mus musculus)
Mammalia Rbm47 16 34 33
  • 87.41 (n)
(Rattus norvegicus)
Mammalia Rbm47 33
  • 86.62 (n)
(Gallus gallus)
Aves RBM47 34 33
  • 80.17 (n)
(Anolis carolinensis)
Reptilia RBM47 34
  • 87 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rbm47 33
  • 70.63 (n)
(Danio rerio)
Actinopterygii RBM47 34
  • 78 (a)
rbm47 33
  • 73.08 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG17838 34
  • 28 (a)
(Caenorhabditis elegans)
Secernentea hrp-2 34
  • 29 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 50 (a)
Species where no ortholog for RBM47 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RBM47 Gene

Gene Tree for RBM47 (if available)
Gene Tree for RBM47 (if available)
Evolutionary constrained regions (ECRs) for RBM47: view image

Paralogs for RBM47 Gene

Paralogs for RBM47 Gene

(10) SIMAP similar genes for RBM47 Gene using alignment to 11 proteins:

  • B7Z8Z7_HUMAN
  • D6R9D6_HUMAN
  • D6R9M7_HUMAN
  • D6RA49_HUMAN
genes like me logo Genes that share paralogs with RBM47: view

Variants for RBM47 Gene

Sequence variations from dbSNP and Humsavar for RBM47 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000001446 -- 40,472,546(-) G/A intron_variant
rs1000003745 -- 40,632,038(-) C/G/T upstream_transcript_variant
rs1000028296 -- 40,472,502(-) C/T intron_variant
rs10000300 -- 40,464,530(-) G/T intron_variant
rs1000043007 -- 40,427,887(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for RBM47 Gene

Variant ID Type Subtype PubMed ID
dgv935e199 CNV deletion 23128226
dgv936e199 CNV deletion 23128226
esv2661897 CNV deletion 23128226
esv2759248 CNV loss 17122850
esv3563750 CNV deletion 23714750
esv3569394 CNV loss 25503493
esv3600305 CNV loss 21293372
esv3600306 CNV loss 21293372
esv3600307 CNV loss 21293372
esv3600309 CNV loss 21293372
esv3600310 CNV loss 21293372
esv3600311 CNV loss 21293372
esv3600312 CNV loss 21293372
esv3600313 CNV loss 21293372
nsv10482 CNV loss 18304495
nsv10484 CNV loss 18304495
nsv1071974 CNV deletion 25765185
nsv1117074 CNV deletion 24896259
nsv829910 CNV loss 17160897
nsv997983 CNV gain 25217958

Variation tolerance for RBM47 Gene

Residual Variation Intolerance Score: 15.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.12; 38.58% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RBM47 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM47 Gene

Disorders for RBM47 Gene

Additional Disease Information for RBM47

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for RBM47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM47 Gene

Publications for RBM47 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3 58
  4. RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma. (PMID: 26923328) Sakurai T … Koinuma D (Oncogene 2016) 3 58
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58

Products for RBM47 Gene

Sources for RBM47 Gene

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