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Aliases for SMARCAL1 Gene

Aliases for SMARCAL1 Gene

  • SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like 1 2 3 5
  • HepA-Related Protein 2 3 4
  • Sucrose Nonfermenting Protein 2-Like 1 3 4
  • ATP-Driven Annealing Helicase 2 3
  • HHARP 3 4
  • HARP 3 4
  • SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A-Like Protein 1 3
  • SMARCA-Like Protein 1 3
  • EC 3.6.4.- 4

External Ids for SMARCAL1 Gene

Previous GeneCards Identifiers for SMARCAL1 Gene

  • GC02P215378
  • GC02P215998
  • GC02P217241
  • GC02P217481
  • GC02P217102
  • GC02P216985
  • GC02P209131
  • GC02P217277

Summaries for SMARCAL1 Gene

Entrez Gene Summary for SMARCAL1 Gene

  • The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq, Jul 2008]

GeneCards Summary for SMARCAL1 Gene

SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like 1) is a Protein Coding gene. Diseases associated with SMARCAL1 include Schimke Immunoosseous Dysplasia and Atrioventricular Septal Defect. Among its related pathways are PEDF Induced Signaling and Primary Focal Segmental Glomerulosclerosis FSGS. Gene Ontology (GO) annotations related to this gene include helicase activity and annealing helicase activity. An important paralog of this gene is BTAF1.

UniProtKB/Swiss-Prot for SMARCAL1 Gene

  • ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.

Gene Wiki entry for SMARCAL1 Gene

Additional gene information for SMARCAL1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMARCAL1 Gene

Genomics for SMARCAL1 Gene

GeneHancer (GH) Regulatory Elements for SMARCAL1 Gene

Promoters and enhancers for SMARCAL1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J216411 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 671.2 +0.4 358 2.2 HDGF PKNOX1 ARID4B SIN3A DMAP1 IRF4 YY1 POLR2B ZNF766 ZNF213 SMARCAL1 ENSG00000235042 XRCC5 GC02M216466
GH02J216497 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 41.8 +87.0 86978 3.8 FOXA2 SMAD1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 GC02P216499 LOC100507554 RPL37A ENSG00000232485 SMARCAL1 XRCC5 GC02M216502
GH02J216690 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.3 +281.4 281417 7.5 PKNOX1 FEZF1 GLI4 ZNF2 GLIS2 ZNF143 KLF7 ATF7 ZNF263 SP3 IGFBP5 ENSG00000236886 SMARCAL1 XRCC5 IGFBP2
GH02J215429 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 10.9 -978.2 -978190 9.4 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 SLC30A9 FOS FN1 XRCC5 SMARCAL1 RPL10P6 ATIC LOC105373868 GC02P215427
GH02J216107 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 10.3 -300.8 -300803 8.6 HDGF PKNOX1 FOXA2 SMAD1 ARNT MLX ZFP64 ARID4B SIN3A DMAP1 XRCC5 PIR31186 LINC01963 SMARCAL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SMARCAL1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SMARCAL1 gene promoter:
  • CUTL1
  • Arnt
  • AhR
  • RREB-1
  • Gfi-1
  • AML1a

Genomic Locations for SMARCAL1 Gene

Genomic Locations for SMARCAL1 Gene
chr2:216,412,414-216,483,053
(GRCh38/hg38)
Size:
70,640 bases
Orientation:
Plus strand
chr2:217,277,137-217,347,776
(GRCh37/hg19)
Size:
70,640 bases
Orientation:
Plus strand

Genomic View for SMARCAL1 Gene

Genes around SMARCAL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMARCAL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMARCAL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMARCAL1 Gene

Proteins for SMARCAL1 Gene

  • Protein details for SMARCAL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NZC9-SMAL1_HUMAN
    Recommended name:
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
    Protein Accession:
    Q9NZC9
    Secondary Accessions:
    • A6NEH0
    • Q53R00
    • Q96AY1
    • Q9NXQ5
    • Q9UFH3
    • Q9UI93

    Protein attributes for SMARCAL1 Gene

    Size:
    954 amino acids
    Molecular mass:
    105938 Da
    Quaternary structure:
    • Interacts with RPA2; the interaction is direct and mediates the recruitment by the RPA complex of SMARCAL1 to sites of DNA damage.
    SequenceCaution:
    • Sequence=BAA90955.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for SMARCAL1 Gene

neXtProt entry for SMARCAL1 Gene

Post-translational modifications for SMARCAL1 Gene

  • DNA damage-regulated phosphorylation by kinases that may include ATM, ATR and PRKDC.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SMARCAL1 Gene

Domains & Families for SMARCAL1 Gene

Gene Families for SMARCAL1 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins

Protein Domains for SMARCAL1 Gene

Suggested Antigen Peptide Sequences for SMARCAL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NZC9

UniProtKB/Swiss-Prot:

SMAL1_HUMAN :
  • Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
Family:
  • Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
genes like me logo Genes that share domains with SMARCAL1: view

Function for SMARCAL1 Gene

Molecular function for SMARCAL1 Gene

UniProtKB/Swiss-Prot Function:
ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.

Enzyme Numbers (IUBMB) for SMARCAL1 Gene

Phenotypes From GWAS Catalog for SMARCAL1 Gene

Gene Ontology (GO) - Molecular Function for SMARCAL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004386 helicase activity IEA --
GO:0005515 protein binding IPI 19793862
GO:0005524 ATP binding IEA --
GO:0008094 DNA-dependent ATPase activity IMP 18974355
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with SMARCAL1: view
genes like me logo Genes that share phenotypes with SMARCAL1: view

Human Phenotype Ontology for SMARCAL1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SMARCAL1 Gene

MGI Knock Outs for SMARCAL1:

Animal Model Products

CRISPR Products

miRNA for SMARCAL1 Gene

miRTarBase miRNAs that target SMARCAL1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMARCAL1

Clone Products

No data available for Transcription Factor Targets and HOMER Transcription for SMARCAL1 Gene

Localization for SMARCAL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMARCAL1 Gene

Nucleus. Note=Recruited to damaged DNA regions.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SMARCAL1 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for SMARCAL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 18974355
GO:0005654 nucleoplasm IDA --
GO:0005662 colocalizes_with DNA replication factor A complex IDA 19793862
GO:0035861 site of double-strand break IDA 19793862
genes like me logo Genes that share ontologies with SMARCAL1: view

Pathways & Interactions for SMARCAL1 Gene

genes like me logo Genes that share pathways with SMARCAL1: view

Pathways by source for SMARCAL1 Gene

1 BioSystems pathway for SMARCAL1 Gene
1 Cell Signaling Technology pathway for SMARCAL1 Gene

Gene Ontology (GO) - Biological Process for SMARCAL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000733 DNA strand renaturation IEA --
GO:0006259 DNA metabolic process IMP 18974355
GO:0006281 DNA repair IEA --
GO:0006357 regulation of transcription by RNA polymerase II IMP 18974355
GO:0006974 cellular response to DNA damage stimulus IMP 19793862
genes like me logo Genes that share ontologies with SMARCAL1: view

No data available for SIGNOR curated interactions for SMARCAL1 Gene

Drugs & Compounds for SMARCAL1 Gene

No Compound Related Data Available

Transcripts for SMARCAL1 Gene

Unigene Clusters for SMARCAL1 Gene

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMARCAL1

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMARCAL1 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
SP1: -
SP2: - -
SP3:

Relevant External Links for SMARCAL1 Gene

GeneLoc Exon Structure for
SMARCAL1
ECgene alternative splicing isoforms for
SMARCAL1

Expression for SMARCAL1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SMARCAL1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SMARCAL1 Gene

This gene is overexpressed in CD8 Tcells (16.7), Peripheral blood mononuclear cells (16.1), Blymphocyte (10.3), CD4 Tcells (7.9), and Monocytes (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SMARCAL1 Gene



Protein tissue co-expression partners for SMARCAL1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of SMARCAL1 Gene:

SMARCAL1

SOURCE GeneReport for Unigene cluster for SMARCAL1 Gene:

Hs.516674

mRNA Expression by UniProt/SwissProt for SMARCAL1 Gene:

Q9NZC9-SMAL1_HUMAN
Tissue specificity: Ubiquitously expressed, with high levels in testis.

Evidence on tissue expression from TISSUES for SMARCAL1 Gene

  • Liver(4.1)
  • Lung(4.1)
  • Nervous system(2.5)

Phenotype-based relationships between genes and organs from Gene ORGANizer for SMARCAL1 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • endocrine
  • immune
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • head
  • jaw
  • larynx
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • skull
  • thyroid
  • tongue
  • tooth
  • vocal cord
Thorax:
  • chest wall
  • clavicle
  • heart
  • heart valve
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • kidney
Pelvis:
  • pelvis
  • ureter
  • urinary bladder
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • coagulation system
  • hair
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal column
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with SMARCAL1: view

No data available for mRNA differential expression in normal tissues for SMARCAL1 Gene

Orthologs for SMARCAL1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SMARCAL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SMARCAL1 34 33
  • 99.69 (n)
OneToOne
dog
(Canis familiaris)
Mammalia SMARCAL1 34 33
  • 84.77 (n)
OneToOne
cow
(Bos Taurus)
Mammalia SMARCAL1 34 33
  • 81.96 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Smarcal1 33
  • 80.68 (n)
mouse
(Mus musculus)
Mammalia Smarcal1 16 34 33
  • 80.16 (n)
oppossum
(Monodelphis domestica)
Mammalia SMARCAL1 34
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SMARCAL1 34
  • 57 (a)
OneToOne
chicken
(Gallus gallus)
Aves SMARCAL1 34 33
  • 61.32 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SMARCAL1 34
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia smarcal1 33
  • 61.19 (n)
Str.11392 33
zebrafish
(Danio rerio)
Actinopterygii smarcal1 34 33
  • 66 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008426 33
  • 51.52 (n)
fruit fly
(Drosophila melanogaster)
Insecta Marcal1 34 33
  • 50.26 (n)
OneToOne
CG3753 35
  • 40 (a)
worm
(Caenorhabditis elegans)
Secernentea C16A3.1 34 33
  • 48.94 (n)
OneToOne
C16A3.1b 35
  • 37 (a)
C16A3.1c 35
  • 37 (a)
C16A3.1a 35
  • 37 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MOT1 34
  • 10 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons CHR18 33
  • 49.07 (n)
rice
(Oryza sativa)
Liliopsida Os07g0636200 33
  • 48.3 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2015 34
  • 44 (a)
OneToOne
Cin.8418 33
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8418 33
Species where no ortholog for SMARCAL1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SMARCAL1 Gene

ENSEMBL:
Gene Tree for SMARCAL1 (if available)
TreeFam:
Gene Tree for SMARCAL1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SMARCAL1: view image

Paralogs for SMARCAL1 Gene

Paralogs for SMARCAL1 Gene

(1) SIMAP similar genes for SMARCAL1 Gene using alignment to 9 proteins:

  • SMAL1_HUMAN
  • C9J6I8_HUMAN
  • C9J8F8_HUMAN
  • C9JHQ1_HUMAN
  • C9JP32_HUMAN
  • C9JS37_HUMAN
  • H7BYI2_HUMAN
  • H7C051_HUMAN
  • H7C1I3_HUMAN
genes like me logo Genes that share paralogs with SMARCAL1: view

Variants for SMARCAL1 Gene

Sequence variations from dbSNP and Humsavar for SMARCAL1 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1033647652 uncertain-significance, Schimke immunoosseous dysplasia 216,414,780(+) G/A 5_prime_UTR_variant, coding_sequence_variant, missense_variant
rs115172989 likely-benign, Schimke immunoosseous dysplasia 216,412,607(+) A/G 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs11555797 benign, conflicting-interpretations-of-pathogenicity, not specified, Schimke immunoosseous dysplasia 216,415,045(+) G/A 5_prime_UTR_variant, coding_sequence_variant, missense_variant
rs119473033 pathogenic, Schimke immunoosseous dysplasia, Atrioventricular canal defect, Congenital microcephaly, Decreased body weight, Disproportionate short-trunk short stature, Focal segmental glomerulosclerosis, Microcephaly, Short stature, Small for gestational age, Steroid-resistant nephrotic syndrome 216,478,216(+) G/T coding_sequence_variant, stop_gained
rs119473034 pathogenic, Schimke immunoosseous dysplasia 216,414,753(+) C/T 5_prime_UTR_variant, coding_sequence_variant, stop_gained

Structural Variations from Database of Genomic Variants (DGV) for SMARCAL1 Gene

Variant ID Type Subtype PubMed ID
nsv1001603 CNV gain 25217958
nsv1004972 CNV gain 25217958
nsv1005697 CNV loss 25217958
nsv1006201 CNV gain 25217958
nsv3161 CNV insertion 18451855
nsv524480 CNV loss 19592680
nsv834537 CNV loss 17160897

Variation tolerance for SMARCAL1 Gene

Residual Variation Intolerance Score: 50.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.18; 75.88% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SMARCAL1 Gene

Human Gene Mutation Database (HGMD)
SMARCAL1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMARCAL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMARCAL1 Gene

Disorders for SMARCAL1 Gene

MalaCards: The human disease database

(11) MalaCards diseases for SMARCAL1 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

SMAL1_HUMAN
  • Schimke immuno-osseous dysplasia (SIOD) [MIM:242900]: An autosomal recessive pleiotropic disorder characterized by spondyloepiphyseal dysplasia, renal dysfunction and immunodeficiency. Arteriosclerosis may also occur in some case. {ECO:0000269 PubMed:11799392, ECO:0000269 PubMed:18974355, ECO:0000269 PubMed:19793862}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for SMARCAL1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with SMARCAL1: view

No data available for Genatlas for SMARCAL1 Gene

Publications for SMARCAL1 Gene

  1. Cloning and characterization of HARP/SMARCAL1: a prokaryotic HepA-related SNF2 helicase protein from human and mouse. (PMID: 10857751) Coleman MA … Mohrenweiser HW (Genomics 2000) 2 3 4 22 58
  2. The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks. (PMID: 19793861) Bansbach CE … Cortez D (Genes & development 2009) 3 4 22 58
  3. The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart. (PMID: 19793862) Ciccia A … Elledge SJ (Genes & development 2009) 3 4 22 58
  4. The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA. (PMID: 19793863) Yusufzai T … Kadonaga JT (Genes & development 2009) 3 4 22 58
  5. HARP is an ATP-driven annealing helicase. (PMID: 18974355) Yusufzai T … Kadonaga JT (Science (New York, N.Y.) 2008) 2 3 4 58

Products for SMARCAL1 Gene

Sources for SMARCAL1 Gene

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