Aliases for NFIA Gene
External Ids for NFIA Gene
Previous GeneCards Identifiers for NFIA Gene
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for NFIA Gene
NFIA (Nuclear Factor I A) is a Protein Coding gene. Diseases associated with NFIA include Brain Malformations With Or Without Urinary Tract Defects and Chromosome 1P32-P31 Deletion Syndrome. Among its related pathways are RNA Polymerase III Transcription Initiation and Gene Expression. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is NFIB.
UniProtKB/Swiss-Prot for NFIA Gene
Recognizes and binds the palindromic sequence 5-TTGGCNNNNNGCCAA-3 present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.