Aliases for NAGA Gene
External Ids for NAGA Gene
Previous GeneCards Identifiers for NAGA Gene
NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease). [provided by RefSeq, Jul 2008]
GeneCards Summary for NAGA Gene
NAGA (Alpha-N-Acetylgalactosaminidase) is a Protein Coding gene. Diseases associated with NAGA include Kanzaki Disease and Schindler Disease, Type I. Among its related pathways are Globo Sphingolipid Metabolism and Lysosome. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and alpha-galactosidase activity. An important paralog of this gene is GLA.
UniProtKB/Swiss-Prot for NAGA Gene
Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids.