Aliases for MAP6 Gene
External Ids for MAP6 Gene
Previous GeneCards Identifiers for MAP6 Gene
This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MAP6 Gene
MAP6 (Microtubule Associated Protein 6) is a Protein Coding gene. Diseases associated with MAP6 include Tick-Borne Relapsing Fever and Schizophrenia. Gene Ontology (GO) annotations related to this gene include microtubule binding and calmodulin binding. An important paralog of this gene is MAP6D1.
UniProtKB/Swiss-Prot for MAP6 Gene
Involved in microtubule stabilization in many cell types, including neuronal cells (By similarity). Specifically has microtubule cold stabilizing activity (By similarity). Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B (PubMed:24357581). Regulates KIF5A-mediated axonal cargo transport (By similarity). Regulates axonal growth during neuron polarization (By similarity).