Aliases for KIF5B Gene
External Ids for KIF5B Gene
Previous HGNC Symbols for KIF5B Gene
Previous GeneCards Identifiers for KIF5B Gene
GeneCards Summary for KIF5B Gene
KIF5B (Kinesin Family Member 5B) is a Protein Coding gene. Diseases associated with KIF5B include Adenosquamous Cell Lung Carcinoma and Blackwater Fever. Among its related pathways are Golgi-to-ER retrograde transport and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF5C.
UniProtKB/Swiss-Prot for KIF5B Gene
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726).