Aliases for HOXB7 Gene
External Ids for HOXB7 Gene
Previous HGNC Symbols for HOXB7 Gene
Previous GeneCards Identifiers for HOXB7 Gene
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXB7 Gene
HOXB7 (Homeobox B7) is a Protein Coding gene. Diseases associated with HOXB7 include Ovarian Endodermal Sinus Tumor and Ovarian Primitive Germ Cell Tumor. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is HOXA7.
UniProtKB/Swiss-Prot for HOXB7 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.