Aliases for ZNF638 Gene
External Ids for ZNF638 Gene
Previous HGNC Symbols for ZNF638 Gene
Previous GeneCards Identifiers for ZNF638 Gene
The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZNF638 Gene
ZNF638 (Zinc Finger Protein 638) is a Protein Coding gene. Diseases associated with ZNF638 include Cutaneous T Cell Lymphoma. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Developmental Biology. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding.
UniProtKB/Swiss-Prot for ZNF638 Gene
Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1 (By similarity). Binds to cytidine clusters in double-stranded DNA (PubMed:8647861). May also regulate alternative splicing of target genes during adipogenesis (By similarity).