Aliases for GAP43 Gene
External Ids for GAP43 Gene
Previous GeneCards Identifiers for GAP43 Gene
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for GAP43 Gene
GAP43 (Growth Associated Protein 43) is a Protein Coding gene. Diseases associated with GAP43 include Developmental Coordination Disorder and Myositis Fibrosa. Among its related pathways are N-cadherin signaling events and L1CAM interactions. Gene Ontology (GO) annotations related to this gene include calmodulin binding.
UniProtKB/Swiss-Prot for GAP43 Gene
This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.