Aliases for LSM5 Gene
External Ids for LSM5 Gene
Previous GeneCards Identifiers for LSM5 Gene
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]
GeneCards Summary for LSM5 Gene
LSM5 (LSM5 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Deadenylation-dependent mRNA decay. Gene Ontology (GO) annotations related to this gene include RNA binding.
UniProtKB/Swiss-Prot for LSM5 Gene
Plays a role in U6 snRNP assembly and function. Binds to the 3 end of U6 snRNA, thereby facilitating formation of the spliceosomal U4/U6 duplex formation in vitro.