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Aliases for FASN Gene

Aliases for FASN Gene

  • Fatty Acid Synthase 2 3 3 5
  • Short Chain Dehydrogenase/Reductase Family 27X, Member 1 2 3
  • FAS 3 4
  • EC 4
  • SDR27X1 3
  • OA-519 3

External Ids for FASN Gene

Previous GeneCards Identifiers for FASN Gene

  • GC17M079459
  • GC17M9J0077
  • GC17M080572
  • GC17M077629
  • GC17M080037
  • GC17M075436

Summaries for FASN Gene

Entrez Gene Summary for FASN Gene

  • The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]

GeneCards Summary for FASN Gene

FASN (Fatty Acid Synthase) is a Protein Coding gene. Diseases associated with FASN include Partial Fetal Alcohol Syndrome and Fatty Liver Disease. Among its related pathways are Regulation of cholesterol biosynthesis by SREBP (SREBF) and AMP-activated Protein Kinase (AMPK) Signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is OXSM.

UniProtKB/Swiss-Prot for FASN Gene

  • Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.

Tocris Summary for FASN Gene

  • Fatty acid synthase (FASN), EC, is a multienzyme that catalyzes the conversion of acetyl-CoA and malonyl-CoA to the 16-carbon fatty acid palmitate. FASN overexpression and hyperactivity is commonly associated with malignant cells.

Gene Wiki entry for FASN Gene

Additional gene information for FASN Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FASN Gene

Genomics for FASN Gene

GeneHancer (GH) Regulatory Elements for FASN Gene

Promoters and enhancers for FASN Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J082095 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 651.9 -3.5 -3478 13.5 CLOCK MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC SSRP1 FASN CEP131 CCDC57 TBCD HGS LOC105371942 ALYREF ARL2BPP9 ENSG00000262877 GPS1
GH17J082492 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 1.2 -397.2 -397161 6 CLOCK ZFP64 FEZF1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZNF143 FOXK2 GC17M082510 PIR58219 TRX-CAT1-8 TBCD ENSG00000260563 ARL2BPP9 GPS1 NARF-IT1 HGS
GH17J081990 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 1.5 +106.5 106486 2.9 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 PAF1 SP5 GC17P081992 CEP131 ASPSCR1 HGS SLC25A10 DCXR NOTUM PCYT2 GCGR LRRC45
GH17J082094 Enhancer 0.7 FANTOM5 dbSUPER 3 +3.4 3441 0.1 SMAD5 POLR2A RBM22 FASN DUS1L SLC25A10 ASPSCR1 PCYT2 DCXR LRRC45 FOXK2 GCGR MRPL12
GH17J082093 Enhancer 0.6 dbSUPER 0.7 +4.4 4427 1.6 KLF1 SMAD5 RXRA ZBED1 SP1 HIC1 SSRP1 POLR2B POLR2A HNF4A CCDC57 OGFOD3 PIR52438 FASN
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FASN on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the FASN gene promoter:
  • PPAR-alpha
  • PPAR-gamma2
  • PPAR-gamma1
  • ATF

Genomic Locations for FASN Gene

Genomic Locations for FASN Gene
20,000 bases
Minus strand
19,995 bases
Minus strand

Genomic View for FASN Gene

Genes around FASN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FASN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FASN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FASN Gene

Proteins for FASN Gene

  • Protein details for FASN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fatty acid synthase
    Protein Accession:
    Secondary Accessions:
    • Q13479
    • Q16702
    • Q4LE83
    • Q6P4U5
    • Q6SS02
    • Q969R1
    • Q96C68
    • Q96IT0

    Protein attributes for FASN Gene

    2511 amino acids
    Molecular mass:
    273427 Da
    Quaternary structure:
    • Homodimer which is arranged in a head to tail fashion (PubMed:17618296, PubMed:18022563, Ref.27). Interacts with CEACAM1; this interaction is insulin and phosphorylation-dependent; reduces fatty-acid synthase activity (By similarity).
    • The relatively low beta-ketoacyl synthase activity may be attributable to the low 4-phosphopantetheine content of the protein.
    • Sequence=AAB35516.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAC50259.1; Type=Miscellaneous discrepancy; Note=Several sequencing errors.; Evidence={ECO:0000305}; Sequence=BAE06070.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for FASN Gene

neXtProt entry for FASN Gene

Post-translational modifications for FASN Gene

  • Ubiquitination at isoforms=2449, Lys2438, Lys1927, Lys1911, Lys1878, isoforms=1866, Lys1851, isoforms=1739, Lys1704, Lys1495, isoforms=1393, Lys1158, Lys1151, Lys1142, Lys1116, Lys992, isoforms=631, isoforms=326, Lys257, Lys213, and isoforms=41
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for FASN Gene

Domains & Families for FASN Gene

Gene Families for FASN Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Enzymes
  • FDA approved drug targets
  • Plasma proteins
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for FASN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FASN: view

No data available for UniProtKB/Swiss-Prot for FASN Gene

Function for FASN Gene

Molecular function for FASN Gene

UniProtKB/Swiss-Prot Function:
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.
UniProtKB/Swiss-Prot CatalyticActivity:
Acetyl-CoA + n malonyl-CoA + 2n NADPH = a long-chain fatty acid + (n+1) CoA + n CO(2) + 2n NADP(+).
UniProtKB/Swiss-Prot CatalyticActivity:
Acetyl-CoA + [acyl-carrier-protein] = CoA + acetyl-[acyl-carrier-protein].
UniProtKB/Swiss-Prot CatalyticActivity:
Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].
UniProtKB/Swiss-Prot CatalyticActivity:
Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl-[acyl-carrier-protein] + CO(2) + [acyl-carrier-protein].
UniProtKB/Swiss-Prot CatalyticActivity:
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH.
UniProtKB/Swiss-Prot CatalyticActivity:
A (3R)-3-hydroxyacyl-[acyl-carrier protein] = a trans-2-enoyl-[acyl-carrier protein] + H(2)O.
UniProtKB/Swiss-Prot CatalyticActivity:
An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH.
UniProtKB/Swiss-Prot CatalyticActivity:
Oleoyl-[acyl-carrier-protein] + H(2)O = [acyl-carrier-protein] + oleate.
GENATLAS Biochemistry:
fatty acid ethyl ester synthase 1,NADPH dependent

Enzyme Numbers (IUBMB) for FASN Gene

Phenotypes From GWAS Catalog for FASN Gene

Gene Ontology (GO) - Molecular Function for FASN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding HDA 22658674
GO:0003824 catalytic activity IEA --
GO:0004312 fatty acid synthase activity IEA,TAS --
GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity IEA --
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity IEA --
genes like me logo Genes that share ontologies with FASN: view
genes like me logo Genes that share phenotypes with FASN: view

Animal Models for FASN Gene

MGI Knock Outs for FASN:
  • Fasn Fasn<tm1Schi>
  • Fasn Fasn<tm1.1Sem>

Animal Model Products

Clone Products

  • Addgene plasmids for FASN

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FASN Gene

Localization for FASN Gene

Subcellular locations from UniProtKB/Swiss-Prot for FASN Gene

Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FASN gene
Compartment Confidence
plasma membrane 5
extracellular 5
cytosol 5
golgi apparatus 5
mitochondrion 3
peroxisome 2
nucleus 2
cytoskeleton 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (4)
  • Plasma membrane (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for FASN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005739 mitochondrion IEA --
GO:0005794 Golgi apparatus IDA --
GO:0005829 cytosol IDA,TAS --
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with FASN: view

Pathways & Interactions for FASN Gene

genes like me logo Genes that share pathways with FASN: view

SIGNOR curated interactions for FASN Gene

Is activated by:

Gene Ontology (GO) - Biological Process for FASN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001649 osteoblast differentiation HDA 16210410
GO:0006084 acetyl-CoA metabolic process IEA --
GO:0006629 lipid metabolic process IEA --
GO:0006631 fatty acid metabolic process TAS 7835891
GO:0006633 fatty acid biosynthetic process IEA --
genes like me logo Genes that share ontologies with FASN: view

Drugs & Compounds for FASN Gene

(74) Drugs for FASN Gene - From: DrugBank, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Orlistat Approved, Investigational Pharma inhibitor, Target Lipase inhibitor for obesity treatment, Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity 54
Cerulenin Approved Pharma Target, inhibitor 0
Isoniazid Approved, Investigational Pharma 164
oleic acid Approved, Investigational, Vet_approved Pharma Full agonist, Agonist, Activation, Activator 0
Stearic acid Approved, Experimental Pharma 0

(63) Additional Compounds for FASN Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • AcCoA
  • Acetyl coenzyme A
  • S-Acetyl-CoA
  • S-Acetyl-coenzyme A
  • Ac-CoA
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
  • b-NADPH
(R)-3-Hydroxydecanoic acid
(R)-3-Hydroxydodecanoic acid
  • (3R)-3-Hydroxydodecanoic acid
  • (3R)-3-Hydroxylauric acid
  • (R)-3-OH Dodecanoic acid
  • (R)-3-OH Lauric acid
  • (R)-beta-Hydroxydodecanoic acid
(R)-3-Hydroxy-hexadecanoic acid
  • (R)-beta-Hydroxypalmitic acid
  • (R)-b-Hydroxypalmitate
  • (R)-b-Hydroxypalmitic acid
  • (R)-beta-Hydroxypalmitate
  • (R)-β-hydroxypalmitate
genes like me logo Genes that share compounds with FASN: view

Transcripts for FASN Gene

mRNA/cDNA for FASN Gene

Unigene Clusters for FASN Gene

Fatty acid synthase:
Representative Sequences:

Clone Products

  • Addgene plasmids for FASN

Alternative Splicing Database (ASD) splice patterns (SP) for FASN Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22 ^ 23 ^

ExUns: 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32a · 32b ^ 33 ^ 34 ^ 35 ^ 36 ^ 37a · 37b · 37c ^ 38 ^ 39a · 39b · 39c ^ 40a · 40b · 40c ^ 41 ^ 42 ^
SP2: - - - - -
SP4: -
SP5: - - - - - - -

ExUns: 43a · 43b · 43c

Relevant External Links for FASN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FASN Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FASN Gene

mRNA differential expression in normal tissues according to GTEx for FASN Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x8.9), Adipose - Subcutaneous (x6.9), and Breast - Mammary Tissue (x4.9).

Protein differential expression in normal tissues from HIPED for FASN Gene

This gene is overexpressed in Milk (12.0), Liver (8.2), and Breast (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FASN Gene

Protein tissue co-expression partners for FASN Gene

NURSA nuclear receptor signaling pathways regulating expression of FASN Gene:


SOURCE GeneReport for Unigene cluster for FASN Gene:


mRNA Expression by UniProt/SwissProt for FASN Gene:

Tissue specificity: Ubiquitous. Prominent expression in brain, lung, and liver.

Evidence on tissue expression from TISSUES for FASN Gene

  • Liver(5)
  • Nervous system(4.9)
  • Skin(4.8)
  • Eye(4.7)
  • Adrenal gland(4.1)
  • Lung(4.1)
  • Heart(3.5)
  • Intestine(3.2)
  • Blood(2.7)
  • Muscle(2.4)
  • Pancreas(2.4)
genes like me logo Genes that share expression patterns with FASN: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for FASN Gene

Orthologs for FASN Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for FASN Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FASN 34 33
  • 98.79 (n)
(Canis familiaris)
Mammalia FASN 34 33
  • 83.25 (n)
(Bos Taurus)
Mammalia FASN 34 33
  • 81.78 (n)
(Mus musculus)
Mammalia Fasn 16 34 33
  • 80.91 (n)
(Rattus norvegicus)
Mammalia Fasn 33
  • 80.63 (n)
(Monodelphis domestica)
Mammalia FASN 34
  • 75 (a)
(Ornithorhynchus anatinus)
Mammalia FASN 34
  • 74 (a)
(Gallus gallus)
Aves FASN 34 33
  • 64.78 (n)
(Anolis carolinensis)
Reptilia FASN 34
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fasn 33
  • 62.57 (n)
(Danio rerio)
Actinopterygii fasn 34 34
  • 64 (a)
fruit fly
(Drosophila melanogaster)
Insecta v(2)k05816 34 35 33
  • 54.54 (n)
BcDNA:GH07626 35
  • 48 (a)
CG3523 34
  • 42 (a)
CG17374 34 35
  • 37 (a)
(Caenorhabditis elegans)
Secernentea fasn-1 34 33
  • 49.54 (n)
F32H2.5 35
  • 41 (a)
C41A3.1 35
  • 34 (a)
F32H2.6 34
  • 33 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CEM1 34
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 36 (a)
Species where no ortholog for FASN was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FASN Gene

Gene Tree for FASN (if available)
Gene Tree for FASN (if available)
Evolutionary constrained regions (ECRs) for FASN: view image

Paralogs for FASN Gene

Paralogs for FASN Gene

genes like me logo Genes that share paralogs with FASN: view

Variants for FASN Gene

Sequence variations from dbSNP and Humsavar for FASN Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs111918281 uncertain-significance, Epileptic encephalopathy 82,083,990(-) C/T coding_sequence_variant, missense_variant
rs115212667 benign, Epileptic encephalopathy 82,092,928(-) G/A coding_sequence_variant, synonymous_variant
rs115708196 benign, Epileptic encephalopathy 82,083,521(-) C/T coding_sequence_variant, synonymous_variant
rs12946178 likely-benign, benign, not provided, Epileptic encephalopathy 82,089,118(-) C/T coding_sequence_variant, missense_variant
rs140072817 benign, Epileptic encephalopathy 82,082,905(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for FASN Gene

Variant ID Type Subtype PubMed ID
dgv5801n54 CNV loss 21841781
esv1000741 CNV deletion 20482838
esv21913 CNV gain+loss 19812545
esv2666752 CNV deletion 23128226
esv2716470 CNV deletion 23290073
esv2716471 CNV deletion 23290073
nsv1055241 CNV loss 25217958
nsv1121945 CNV deletion 24896259
nsv428351 CNV gain 18775914
nsv457975 CNV loss 19166990
nsv457976 CNV gain 19166990
nsv470621 CNV gain 18288195
nsv576183 CNV loss 21841781
nsv576187 CNV gain 21841781
nsv952393 CNV deletion 24416366

Variation tolerance for FASN Gene

Residual Variation Intolerance Score: 1.84% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.91; 74.38% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FASN Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FASN Gene

Disorders for FASN Gene

MalaCards: The human disease database

(6) MalaCards diseases for FASN Gene - From: HGMD, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
partial fetal alcohol syndrome
fatty liver disease
  • steatosis of liver
prostate cancer
  • prostate cancer, susceptibility to
body mass index quantitative trait locus 11
  • bmiq11
breast cancer
  • breast cancer, familial
- elite association - COSMIC cancer census association via MalaCards
Search FASN in MalaCards View complete list of genes associated with diseases

Additional Disease Information for FASN

Genetic Association Database
Human Genome Epidemiology Navigator
Tumor Gene Database
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with FASN: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FASN Gene

Publications for FASN Gene

  1. Human fatty acid synthase: properties and molecular cloning. (PMID: 7567999) Jayakumar A … Wakil SJ (Proceedings of the National Academy of Sciences of the United States of America 1995) 2 3 4 22 58
  2. Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression. (PMID: 19876008) Schleinitz D … Kovacs P (Obesity (Silver Spring, Md.) 2010) 3 22 44 58
  3. Val1483Ile in FASN gene is linked to central obesity and insulin sensitivity in adult white men. (PMID: 19300427) Moreno-Navarrete JM … Fernández-Real JM (Obesity (Silver Spring, Md.) 2009) 3 22 44 58
  4. Genetic variation in genes of the fatty acid synthesis pathway and breast cancer risk. (PMID: 19252981) Campa D … Kaaks R (Breast cancer research and treatment 2009) 3 22 44 58
  5. Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. (PMID: 17618296) Pemble CW … Lowther WT (Nature structural & molecular biology 2007) 3 4 22 58

Products for FASN Gene

  • Addgene plasmids for FASN

Sources for FASN Gene