Aliases for ELF2 Gene
Previous GeneCards Identifiers for ELF2 Gene
GeneCards Summary for ELF2 Gene
ELF2 (E74 Like ETS Transcription Factor 2) is a Protein Coding gene. Diseases associated with ELF2 include Peroneal Neuropathy and Peroneal Nerve Paralysis. Among its related pathways are ADP signalling through P2Y purinoceptor 12 and Immune response IL-23 signaling pathway. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ELF1.
UniProtKB/Swiss-Prot for ELF2 Gene
Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.
Isoform 2 may function in repression of RUNX1-mediated transactivation.