Aliases for PPP1R18 Gene
External Ids for PPP1R18 Gene
Previous HGNC Symbols for PPP1R18 Gene
Previous GeneCards Identifiers for PPP1R18 Gene
Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008]
GeneCards Summary for PPP1R18 Gene
PPP1R18 (Protein Phosphatase 1 Regulatory Subunit 18) is a Protein Coding gene. Diseases associated with PPP1R18 include Deafness, Autosomal Recessive 79. Gene Ontology (GO) annotations related to this gene include actin binding and phosphatase binding. An important paralog of this gene is TPRN.
UniProtKB/Swiss-Prot for PPP1R18 Gene
Isoform 1: May target protein phosphatase 1 to F-actin cytoskeleton.
Isoform 4: May target protein phosphatase 1 to F-actin cytoskeleton.