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Aliases for CLTC Gene

Aliases for CLTC Gene

  • Clathrin Heavy Chain 2 3 5
  • Clathrin Heavy Chain On Chromosome 17 3 4
  • Clathrin, Heavy Polypeptide-Like 2 2 3
  • Clathrin, Heavy Polypeptide (Hc) 2 3
  • CLTCL2 3 4
  • CLH-17 3 4
  • Clathrin, Heavy Chain (Hc) 2
  • Clathrin Heavy Chain 1 3
  • Clathrin, Heavy Chain 2
  • KIAA0034 4
  • CHC17 3
  • MRD56 3
  • CLH17 4
  • CHC 3
  • Hc 3

External Ids for CLTC Gene

Previous HGNC Symbols for CLTC Gene

  • CLTCL2

Previous GeneCards Identifiers for CLTC Gene

  • GC17P057433
  • GC17P060146
  • GC17P058039
  • GC17P058171
  • GC17P055052
  • GC17P057697
  • GC17P053069

Summaries for CLTC Gene

Entrez Gene Summary for CLTC Gene

  • Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008]

GeneCards Summary for CLTC Gene

CLTC (Clathrin Heavy Chain) is a Protein Coding gene. Diseases associated with CLTC include Mental Retardation, Autosomal Dominant 56 and Inflammatory Myofibroblastic Tumor. Among its related pathways are wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF) and Cytoskeletal Signaling. Gene Ontology (GO) annotations related to this gene include protein kinase binding. An important paralog of this gene is CLTCL1.

UniProtKB/Swiss-Prot for CLTC Gene

  • Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577, PubMed:16968737, PubMed:21297582). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Plays a role in early autophagosome formation (PubMed:20639872).

Gene Wiki entry for CLTC Gene

Additional gene information for CLTC Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLTC Gene

Genomics for CLTC Gene

GeneHancer (GH) Regulatory Elements for CLTC Gene

Promoters and enhancers for CLTC Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J059616 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 650.7 0.0 -14 6.8 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 CLTC ENSG00000273702 TUBD1 RPS6KB1 HEATR6 SKA2 PPM1D DHX40 RNFT1 NDUFB8P2
GH17J059824 Promoter/Enhancer 2.8 VISTA FANTOM5 Ensembl ENCODE dbSUPER 5.5 +223.2 223197 36.2 MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 GC17P059845 MIR21 GC17M059843 GC17M059842 GC17M059841 GC17P059844 GC17P059843 GC17P059842 PPM1D TUBD1
GH17J060523 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 5.7 +905.8 905812 3.4 HDGF PKNOX1 SMAD1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 APPBP2 ENSG00000259349 KRT18P61 TBC1D3P1-DHX40P1 TBC1D3P1 DHX40P1 RPS29P21 CLTC GC17P060514
GH17J060467 Enhancer 1.1 Ensembl ENCODE 5.7 +849.6 849604 3 HDGF PKNOX1 ATF1 SMAD1 ARNT YY1 TCF12 ZNF121 ZNF766 E2F8 HEATR6 RPL32P32 PPM1D TUBD1 CLTC APPBP2 GC17M060489 RPL12P38
GH17J060505 Enhancer 0.9 Ensembl ENCODE 5.7 +886.8 886849 2.1 BACH1 ZNF2 ZNF316 NFE2 MAFK ZNF362 SP3 MAFG DPF2 ATF2 GC17M060506 CLTC APPBP2 GC17M060489
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CLTC on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CLTC gene promoter:
  • STAT1
  • AP-2alphaA
  • AP-2alpha isoform 4
  • AP-2alpha isoform 3
  • AP-2alpha isoform 2
  • AP-2alpha
  • MyoD

Genomic Locations for CLTC Gene

Genomic Locations for CLTC Gene
chr17:59,619,689-59,696,956
(GRCh38/hg38)
Size:
77,268 bases
Orientation:
Plus strand
chr17:57,697,050-57,774,317
(GRCh37/hg19)
Size:
77,268 bases
Orientation:
Plus strand

Genomic View for CLTC Gene

Genes around CLTC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CLTC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CLTC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLTC Gene

Proteins for CLTC Gene

  • Protein details for CLTC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q00610-CLH1_HUMAN
    Recommended name:
    Clathrin heavy chain 1
    Protein Accession:
    Q00610
    Secondary Accessions:
    • D3DU00
    • Q6N0A0
    • Q86TF2

    Protein attributes for CLTC Gene

    Size:
    1675 amino acids
    Molecular mass:
    191615 Da
    Quaternary structure:
    • Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat (PubMed:16968737). In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium. Interacts with HIP1 (PubMed:11532990). Interacts with DENND1A, DENND1B and DENND1C (By similarity). May interact with OCRL (By similarity). Interacts with ERBB2 (PubMed:16314522). Interacts with FKBP6 (PubMed:18529014). Interacts with CKAP5 and TACC3 forming the TACC3/ch-TOG/clathrin complex located at spindle inter-microtubules bridges; the complex implicates clathrin triskelions; TACC3 and CLTC are proposed to form a composite microtubule interaction surface (PubMed:21297582). Interacts with ATG16L1 (via N-terminus) (PubMed:20639872). Interacts with RFTN1; the interaction occurs in response to pathogens (PubMed:27022195, PubMed:21266579). Interacts with USP2 isoform 4 (PubMed:26756164).
    SequenceCaution:
    • Sequence=BAA04801.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for CLTC Gene

    Alternative splice isoforms for CLTC Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CLTC Gene

Post-translational modifications for CLTC Gene

  • Ubiquitination at Lys1443, posLast=12151215, posLast=11791179, Lys1074, Lys941, Lys881, Lys856, posLast=798798, posLast=389389, posLast=367367, and Lys163
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CLTC Gene

Domains & Families for CLTC Gene

Gene Families for CLTC Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Plasma proteins
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for CLTC Gene

Graphical View of Domain Structure for InterPro Entry

Q00610

UniProtKB/Swiss-Prot:

CLH1_HUMAN :
  • The N-terminal seven-bladed beta-propeller is formed by WD40-like repeats, and projects inward from the polyhedral outer clathrin coat. It constitutes a major protein-protein interaction node.
  • Belongs to the clathrin heavy chain family.
Domain:
  • The N-terminal seven-bladed beta-propeller is formed by WD40-like repeats, and projects inward from the polyhedral outer clathrin coat. It constitutes a major protein-protein interaction node.
Family:
  • Belongs to the clathrin heavy chain family.
genes like me logo Genes that share domains with CLTC: view

Function for CLTC Gene

Molecular function for CLTC Gene

UniProtKB/Swiss-Prot Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577, PubMed:16968737, PubMed:21297582). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Plays a role in early autophagosome formation (PubMed:20639872).
GENATLAS Biochemistry:
clathrin,heavy chain 1,ubiquitously expressed,component of coated vesicles and coated pits,translocated to plasma membrane through AP2 binding,also expressed in synaptic vesicles

Phenotypes From GWAS Catalog for CLTC Gene

Gene Ontology (GO) - Molecular Function for CLTC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding HDA 22681889
GO:0003725 double-stranded RNA binding IDA 21266579
GO:0005198 structural molecule activity NAS,IEA 1765375
GO:0005488 binding IEA --
GO:0005515 protein binding IEA,IPI 12429846
genes like me logo Genes that share ontologies with CLTC: view
genes like me logo Genes that share phenotypes with CLTC: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLTC

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CLTC Gene

Localization for CLTC Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLTC Gene

Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Melanosome. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In complex with TACC3 and CKAP5 (forming the TACC3/ch-TOG/clathrin complex) localized to inter-microtubule bridges in mitotic spindles. {ECO:0000269 PubMed:25596274}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CLTC gene
Compartment Confidence
extracellular 5
cytoskeleton 5
cytosol 5
golgi apparatus 5
endosome 5
plasma membrane 4
lysosome 4
peroxisome 1
nucleus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Vesicles (4)
  • Mitotic spindle (3)
  • Cytosol (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CLTC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005737 cytoplasm IEA --
GO:0005764 lysosome IDA --
GO:0005768 endosome IDA --
GO:0005819 spindle IEA,IDA 15858577
genes like me logo Genes that share ontologies with CLTC: view

Pathways & Interactions for CLTC Gene

genes like me logo Genes that share pathways with CLTC: view

SIGNOR curated interactions for CLTC Gene

Is activated by:

Gene Ontology (GO) - Biological Process for CLTC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000278 mitotic cell cycle IMP 15858577
GO:0001649 osteoblast differentiation HDA 16210410
GO:0006886 intracellular protein transport IEA,NAS 1765375
GO:0006898 receptor-mediated endocytosis IMP 15858577
GO:0006914 autophagy IEA --
genes like me logo Genes that share ontologies with CLTC: view

Drugs & Compounds for CLTC Gene

(1) Drugs for CLTC Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
calcium Approved Nutra 0
genes like me logo Genes that share compounds with CLTC: view

Transcripts for CLTC Gene

mRNA/cDNA for CLTC Gene

Unigene Clusters for CLTC Gene

Clathrin, heavy chain (Hc):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLTC

Alternative Splicing Database (ASD) splice patterns (SP) for CLTC Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^
SP1: - - - - -
SP2: - - - -
SP3: - - - - -
SP4:
SP5:
SP6:
SP7: - -
SP8:
SP9:
SP10:
SP11:

ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29a · 29b ^ 30 ^ 31a · 31b ^ 32 ^ 33a · 33b ^ 34a · 34b · 34c ^ 35a · 35b · 35c
SP1: - - - -
SP2: - - - -
SP3: - - -
SP4:
SP5: - - -
SP6: - - - - -
SP7:
SP8:
SP9:
SP10:
SP11: -

Relevant External Links for CLTC Gene

GeneLoc Exon Structure for
CLTC
ECgene alternative splicing isoforms for
CLTC

Expression for CLTC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CLTC Gene

Protein differential expression in normal tissues from HIPED for CLTC Gene

This gene is overexpressed in Frontal cortex (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CLTC Gene



Protein tissue co-expression partners for CLTC Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CLTC Gene:

CLTC

SOURCE GeneReport for Unigene cluster for CLTC Gene:

Hs.491351

Evidence on tissue expression from TISSUES for CLTC Gene

  • Heart(5)
  • Liver(5)
  • Nervous system(5)
  • Blood(4.8)
  • Intestine(4.7)
  • Bone marrow(4.4)
  • Eye(4.3)
  • Adrenal gland(3.9)
  • Kidney(3.8)
  • Lung(3.8)
  • Pancreas(3.8)
  • Skin(3.6)
  • Gall bladder(3.3)
  • Muscle(3.3)
  • Lymph node(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for CLTC Gene

Germ Layers:
  • mesoderm
Systems:
  • urinary
Regions:
Abdomen:
  • kidney
genes like me logo Genes that share expression patterns with CLTC: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CLTC Gene

Orthologs for CLTC Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CLTC Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia CLTC 34
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CLTC 34 33
  • 99.78 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 99 (a)
OneToMany
-- 34
  • 96 (a)
OneToMany
dog
(Canis familiaris)
Mammalia CLTC 34 33
  • 95.28 (n)
OneToOne
cow
(Bos Taurus)
Mammalia CLTC 34 33
  • 94.03 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Cltc 16 34 33
  • 92.02 (n)
rat
(Rattus norvegicus)
Mammalia Cltc 33
  • 91.22 (n)
chicken
(Gallus gallus)
Aves CLTC 34 33
  • 84.02 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CLTC 34
  • 98 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cltc 33
  • 81.99 (n)
Str.11060 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.23823 33
zebrafish
(Danio rerio)
Actinopterygii cltca 34
  • 95 (a)
OneToMany
cltcb 34 33
  • 78.97 (n)
OneToMany
CLTC (2 of 3) 34
  • 78 (a)
OneToMany
wufc49a11 33
fruit fly
(Drosophila melanogaster)
Insecta Chc 34 35 33
  • 67.91 (n)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003021 33
  • 67.13 (n)
worm
(Caenorhabditis elegans)
Secernentea T20G5.1 35
  • 71 (a)
chc-1 34 33
  • 64.92 (n)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CHC1 36 34 33
  • 55.51 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F09911g 33
  • 54.62 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AER359W 33
  • 53.86 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G08530 33
  • 58.85 (n)
soybean
(Glycine max)
eudicotyledons Gma.5822 33
wheat
(Triticum aestivum)
Liliopsida Ta.5000 33
barley
(Hordeum vulgare)
Liliopsida Hv.1410 33
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1583 34
  • 66 (a)
OneToMany
Cin.4438 33
bread mold
(Neurospora crassa)
Ascomycetes NCU02510 33
  • 57.97 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes chc1 33
  • 57.62 (n)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4438 33
Species where no ortholog for CLTC was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for CLTC Gene

ENSEMBL:
Gene Tree for CLTC (if available)
TreeFam:
Gene Tree for CLTC (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CLTC: view image

Paralogs for CLTC Gene

Paralogs for CLTC Gene

(1) SIMAP similar genes for CLTC Gene using alignment to 8 proteins:

  • CLH1_HUMAN
  • J3KRF5_HUMAN
  • J3KS13_HUMAN
  • J3KSQ2_HUMAN
  • J3KTN1_HUMAN
  • J3QL20_HUMAN
  • K7EJJ5_HUMAN
  • Q49AL0_HUMAN
genes like me logo Genes that share paralogs with CLTC: view

Variants for CLTC Gene

Sequence variations from dbSNP and Humsavar for CLTC Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs797044884 likely-pathogenic, pathogenic, Inborn genetic diseases, MENTAL RETARDATION, AUTOSOMAL DOMINANT 56 59,677,124(+) AGAGAGA/AGAGAGAGA coding_sequence_variant, frameshift
rs750846632 likely-pathogenic, not provided 59,681,058(+) G/A/T splice_donor_variant
rs1000015546 -- 59,621,714(+) C/T intron_variant
rs1000124265 -- 59,658,261(+) C/T intron_variant
rs1000156927 -- 59,631,484(+) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CLTC Gene

Variant ID Type Subtype PubMed ID
dgv3272n100 CNV gain 25217958
esv2672443 CNV deletion 23128226
esv3640907 CNV loss 21293372
esv3640908 CNV loss 21293372
esv3640909 CNV loss 21293372
nsv1067453 CNV gain 25217958
nsv575805 CNV gain 21841781
nsv833501 CNV loss 17160897

Variation tolerance for CLTC Gene

Residual Variation Intolerance Score: 1.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.95; 19.59% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CLTC Gene

Human Gene Mutation Database (HGMD)
CLTC
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CLTC

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CLTC Gene

Disorders for CLTC Gene

MalaCards: The human disease database

(7) MalaCards diseases for CLTC Gene - From: HGMD, OMIM, ClinVar, Orphanet, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search CLTC in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CLTC

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CLTC: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CLTC Gene

Publications for CLTC Gene

  1. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PMID: 7584026) Nomura N … Tabata S (DNA research : an international journal for rapid publication of reports on genes and genomes 1994) 2 3 4 58
  2. Human clathrin heavy chain (CLTC): partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter. (PMID: 1765375) Dodge GR … Iozzo RV (Genomics 1991) 2 3 4 58
  3. USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level. (PMID: 26756164) Pouly D … Staub O (PloS one 2016) 3 4 58
  4. A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. (PMID: 21297582) Booth DG … Royle SJ (The EMBO journal 2011) 3 4 58
  5. Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. (PMID: 21266579) Watanabe A … Matsumoto M (The Journal of biological chemistry 2011) 3 4 58

Products for CLTC Gene

Sources for CLTC Gene

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