Aliases for SNUPN Gene
External Ids for SNUPN Gene
Previous HGNC Symbols for SNUPN Gene
Previous GeneCards Identifiers for SNUPN Gene
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for SNUPN Gene
SNUPN (Snurportin 1) is a Protein Coding gene. Among its related pathways are Transport of the SLBP independent Mature mRNA and RNA transport. Gene Ontology (GO) annotations related to this gene include protein transporter activity and RNA cap binding.
UniProtKB/Swiss-Prot for SNUPN Gene
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.