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Aliases for ZNF560 Gene

Aliases for ZNF560 Gene

  • Zinc Finger Protein 560 2 3 3 5

External Ids for ZNF560 Gene

Previous GeneCards Identifiers for ZNF560 Gene

  • GC19M009268
  • GC19M009438
  • GC19M009577
  • GC19M009158
  • GC19M009466

Summaries for ZNF560 Gene

GeneCards Summary for ZNF560 Gene

ZNF560 (Zinc Finger Protein 560) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF778.

UniProtKB/Swiss-Prot for ZNF560 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF560 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF560 Gene

Genomics for ZNF560 Gene

GeneHancer (GH) Regulatory Elements for ZNF560 Gene

Promoters and enhancers for ZNF560 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J009497 Promoter/Enhancer 1.2 EPDnew Ensembl ENCODE 656.6 +8.2 8231 0.9 CTCF GABPB1 ZBTB33 ZBTB40 CREM ZNF560 ENSG00000267273 ENSG00000267612 GC19P009479 PIR32922
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF560 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF560 gene promoter:

Genomic Locations for ZNF560 Gene

Genomic Locations for ZNF560 Gene
chr19:9,445,826-9,506,689
(GRCh38/hg38)
Size:
60,864 bases
Orientation:
Minus strand
chr19:9,577,031-9,609,283
(GRCh37/hg19)

Genomic View for ZNF560 Gene

Genes around ZNF560 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF560 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF560 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF560 Gene

Proteins for ZNF560 Gene

  • Protein details for ZNF560 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MR9-ZN560_HUMAN
    Recommended name:
    Zinc finger protein 560
    Protein Accession:
    Q96MR9
    Secondary Accessions:
    • Q495S9
    • Q495T1

    Protein attributes for ZNF560 Gene

    Size:
    790 amino acids
    Molecular mass:
    91121 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF560 Gene

Post-translational modifications for ZNF560 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF560 Gene

Domains & Families for ZNF560 Gene

Gene Families for ZNF560 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF560 Gene

Suggested Antigen Peptide Sequences for ZNF560 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96MR9

UniProtKB/Swiss-Prot:

ZN560_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF560: view

Function for ZNF560 Gene

Molecular function for ZNF560 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF560 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0043565 sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF560: view
genes like me logo Genes that share phenotypes with ZNF560: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF560 Gene

Localization for ZNF560 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF560 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF560 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF560 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF560: view

Pathways & Interactions for ZNF560 Gene

SuperPathways for ZNF560 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF560: view

Pathways by source for ZNF560 Gene

2 Reactome pathways for ZNF560 Gene

Interacting Proteins for ZNF560 Gene

Gene Ontology (GO) - Biological Process for ZNF560 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF560: view

No data available for SIGNOR curated interactions for ZNF560 Gene

Drugs & Compounds for ZNF560 Gene

No Compound Related Data Available

Transcripts for ZNF560 Gene

mRNA/cDNA for ZNF560 Gene

(7) Selected AceView cDNA sequences:
(5) Additional mRNA sequences :
(9) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF560 Gene

Zinc finger protein 560:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF560 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b
SP1:
SP2:

Relevant External Links for ZNF560 Gene

GeneLoc Exon Structure for
ZNF560
ECgene alternative splicing isoforms for
ZNF560

Expression for ZNF560 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF560 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF560 Gene

This gene is overexpressed in Testis (x40.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF560 Gene



Protein tissue co-expression partners for ZNF560 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF560 Gene:

ZNF560

SOURCE GeneReport for Unigene cluster for ZNF560 Gene:

Hs.631613
genes like me logo Genes that share expression patterns with ZNF560: view

No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF560 Gene

Orthologs for ZNF560 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF560 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF560 34 33
  • 98.44 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp560 16 34 33
  • 67.3 (n)
rat
(Rattus norvegicus)
Mammalia Zfp560 33
  • 67.02 (n)
cow
(Bos Taurus)
Mammalia -- 34
  • 36 (a)
OneToMany
Species where no ortholog for ZNF560 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF560 Gene

ENSEMBL:
Gene Tree for ZNF560 (if available)
TreeFam:
Gene Tree for ZNF560 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF560: view image

Paralogs for ZNF560 Gene

Paralogs for ZNF560 Gene

(307) SIMAP similar genes for ZNF560 Gene using alignment to 1 proteins:

  • ZN560_HUMAN
genes like me logo Genes that share paralogs with ZNF560: view

Variants for ZNF560 Gene

Sequence variations from dbSNP and Humsavar for ZNF560 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs193920939 uncertain-significance, Malignant tumor of prostate 9,467,851(-) G/A/T coding_sequence_variant, missense_variant
VAR_035588 A colorectal cancer sample p.Gly186Glu
rs1000002683 -- 9,469,416(-) A/C intron_variant
rs1000020831 -- 9,456,136(-) A/C genic_downstream_transcript_variant, intron_variant
rs1000110503 -- 9,475,810(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF560 Gene

Variant ID Type Subtype PubMed ID
esv3343658 CNV insertion 20981092
esv995010 CNV deletion 20482838
nsv1131397 CNV deletion 24896259

Variation tolerance for ZNF560 Gene

Residual Variation Intolerance Score: 19.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.29; 40.98% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF560 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF560

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF560 Gene

Disorders for ZNF560 Gene

Additional Disease Information for ZNF560

No disorders were found for ZNF560 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF560 Gene

Publications for ZNF560 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Screening for differentially expressed genes between left- and right-sided colon carcinoma by microarray analysis. (PMID: 24137329) Zhu H … Pei HP (Oncology letters 2013) 3 58
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  5. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjöblom T … Velculescu VE (Science (New York, N.Y.) 2006) 4 58

Products for ZNF560 Gene

Sources for ZNF560 Gene

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