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Aliases for KHDRBS3 Gene

Aliases for KHDRBS3 Gene

  • KH RNA Binding Domain Containing, Signal Transduction Associated 3 2 3 5
  • KH Domain Containing, RNA Binding, Signal Transduction Associated 3 2 3
  • Sam68-Like Mammalian Protein 2 3 4
  • RNA-Binding Protein T-Star 3 4
  • SLM-2 3 4
  • SALP 3 4
  • SLM2 3 4
  • KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3 3
  • Sam68-Like Phosphotyrosine Protein, T-STAR 3
  • Sam68-Like Phosphotyrosine Protein 4
  • T-STAR 3
  • Etoile 3
  • TSTAR 3
  • Etle 3

External Ids for KHDRBS3 Gene

Previous GeneCards Identifiers for KHDRBS3 Gene

  • GC08P135242
  • GC08P136579
  • GC08P136154
  • GC08P136440
  • GC08P136538
  • GC08P131785

Summaries for KHDRBS3 Gene

GeneCards Summary for KHDRBS3 Gene

KHDRBS3 (KH RNA Binding Domain Containing, Signal Transduction Associated 3) is a Protein Coding gene. Diseases associated with KHDRBS3 include Transvestism and Fetishism. Among its related pathways are Signaling by PTK6 and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is KHDRBS2.

UniProtKB/Swiss-Prot for KHDRBS3 Gene

  • RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5-[AU]UAAA-3 motif in vitro. Binds optimally to RNA containing 5-[AU]UAA-3 as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 (PubMed:10564820, PubMed:19561594, PubMed:26758068). Involved in splice site selection of vascular endothelial growth factor (PubMed:15901763). In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members (PubMed:26758068). Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity). May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity). Can bind FABP9 mRNA (By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation.

  • (Microbial infection) Involved in post-transcriptional regulation of HIV-1 gene expression.

Gene Wiki entry for KHDRBS3 Gene

Additional gene information for KHDRBS3 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KHDRBS3 Gene

Genomics for KHDRBS3 Gene

GeneHancer (GH) Regulatory Elements for KHDRBS3 Gene

Promoters and enhancers for KHDRBS3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J135455 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 650.7 -0.2 -164 3.4 ARID4B SIN3A DMAP1 YY1 GLIS2 ZNF143 ATF7 REST KAT8 PPARGC1A LOC101927872 KHDRBS3 PIR45588
GH08J135459 Promoter 0.8 Ensembl 650.7 +1.7 1743 0.4 SAP130 ZBTB11 KLF9 ZBTB20 KHDRBS3 LOC101927872 GC08P135499
GH08J136041 Enhancer 1 ENCODE dbSUPER 6.9 +584.6 584606 1.8 ELF3 FOXA2 RAD21 THRB ZNF48 ZSCAN9 RARA ETS1 SLC30A9 ZNF614 KHDRBS3 ENSG00000253248 PIR45810
GH08J136028 Enhancer 0.9 dbSUPER 7.1 +572.6 572646 3.7 FOXA2 MLX ARID4B DMAP1 ETS1 NFKBIZ RXRA SP5 MIER2 PPARG KHDRBS3 ENSG00000253248 PIR45810
GH08J136048 Enhancer 0.9 ENCODE 7 +591.7 591723 2.2 ELF3 FOXA2 MLX ARID4B DMAP1 RAD21 THRB ZNF48 ZSCAN9 RARA KHDRBS3 ENSG00000253248 LOC105375775
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KHDRBS3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KHDRBS3 gene promoter:
  • NRSF form 1
  • NRSF form 2
  • GR
  • GR-alpha
  • p300

Genomic Locations for KHDRBS3 Gene

Genomic Locations for KHDRBS3 Gene
chr8:135,457,457-135,656,722
(GRCh38/hg38)
Size:
199,266 bases
Orientation:
Plus strand
chr8:136,469,700-136,668,965
(GRCh37/hg19)
Size:
199,266 bases
Orientation:
Plus strand

Genomic View for KHDRBS3 Gene

Genes around KHDRBS3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KHDRBS3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KHDRBS3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KHDRBS3 Gene

Proteins for KHDRBS3 Gene

  • Protein details for KHDRBS3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75525-KHDR3_HUMAN
    Recommended name:
    KH domain-containing, RNA-binding, signal transduction-associated protein 3
    Protein Accession:
    O75525
    Secondary Accessions:
    • Q6NUL8
    • Q9UPA8

    Protein attributes for KHDRBS3 Gene

    Size:
    346 amino acids
    Molecular mass:
    38800 Da
    Quaternary structure:
    • Self-associates to form homooligomers; dimerization increases RNA affinity (PubMed:26758068). Interacts with KHDRBS2/SLM-1 (By similarity). Interacts with KHDRBS1/SAM68; heterooligomer formation of KHDRBS family proteins may modulate RNA substrate specificity (PubMed:10332027). Interacts with the splicing regulatory proteins SFRS9, SAFB and YTHDC1. Interacts with HNRPL (By similarity). Interacts with RBMX, RBMY1A1, p85 subunit of PI3-kinase, SERPINB5 (PubMed:10564820, PubMed:10332027, PubMed:10749975, PubMed:21725612). Interacts with SIAH1 which promotes targeting for degradation (PubMed:15163637).

    Three dimensional structures from OCA and Proteopedia for KHDRBS3 Gene

    Alternative splice isoforms for KHDRBS3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KHDRBS3 Gene

Post-translational modifications for KHDRBS3 Gene

  • Phosphorylated on tyrosine residues. Isoform 1 C-terminal region is tyrosine-rich, but isoform 2 lacking this C-terminal region is also tyrosine-phosphorylated.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KHDRBS3 Gene

Domains & Families for KHDRBS3 Gene

Gene Families for KHDRBS3 Gene

Protein Domains for KHDRBS3 Gene

Suggested Antigen Peptide Sequences for KHDRBS3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75525

UniProtKB/Swiss-Prot:

KHDR3_HUMAN :
  • The proline-rich site binds the SH3 domain of the p85 subunit of PI3-kinase.
  • Belongs to the KHDRBS family.
Domain:
  • The proline-rich site binds the SH3 domain of the p85 subunit of PI3-kinase.
Family:
  • Belongs to the KHDRBS family.
genes like me logo Genes that share domains with KHDRBS3: view

Function for KHDRBS3 Gene

Molecular function for KHDRBS3 Gene

UniProtKB/Swiss-Prot Function:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5-[AU]UAAA-3 motif in vitro. Binds optimally to RNA containing 5-[AU]UAA-3 as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 (PubMed:10564820, PubMed:19561594, PubMed:26758068). Involved in splice site selection of vascular endothelial growth factor (PubMed:15901763). In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members (PubMed:26758068). Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity). May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity). Can bind FABP9 mRNA (By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation.
UniProtKB/Swiss-Prot Function:
(Microbial infection) Involved in post-transcriptional regulation of HIV-1 gene expression.
UniProtKB/Swiss-Prot Induction:
Induced in proteinuric diseases. Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death.

Phenotypes From GWAS Catalog for KHDRBS3 Gene

Gene Ontology (GO) - Molecular Function for KHDRBS3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IEA,IDA 19561594
GO:0005515 protein binding IPI 10332027
GO:0017124 SH3 domain binding IEA --
GO:0019904 protein domain specific binding IPI 10332027
GO:0042802 identical protein binding IDA 10332027
genes like me logo Genes that share ontologies with KHDRBS3: view
genes like me logo Genes that share phenotypes with KHDRBS3: view

Animal Models for KHDRBS3 Gene

MGI Knock Outs for KHDRBS3:

Animal Model Products

CRISPR Products

miRNA for KHDRBS3 Gene

miRTarBase miRNAs that target KHDRBS3

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KHDRBS3

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KHDRBS3 Gene

Localization for KHDRBS3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KHDRBS3 Gene

Nucleus. Note=Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KHDRBS3 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for KHDRBS3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IMP 10332027
GO:0005654 nucleoplasm IDA,TAS --
genes like me logo Genes that share ontologies with KHDRBS3: view

Pathways & Interactions for KHDRBS3 Gene

genes like me logo Genes that share pathways with KHDRBS3: view

Pathways by source for KHDRBS3 Gene

Gene Ontology (GO) - Biological Process for KHDRBS3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006397 mRNA processing IEA --
GO:0048024 regulation of mRNA splicing, via spliceosome IEA --
GO:0051259 protein complex oligomerization IDA 10332027
genes like me logo Genes that share ontologies with KHDRBS3: view

No data available for SIGNOR curated interactions for KHDRBS3 Gene

Drugs & Compounds for KHDRBS3 Gene

(5) Drugs for KHDRBS3 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(1) Additional Compounds for KHDRBS3 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with KHDRBS3: view

Transcripts for KHDRBS3 Gene

Unigene Clusters for KHDRBS3 Gene

KH domain containing, RNA binding, signal transduction associated 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KHDRBS3

Alternative Splicing Database (ASD) splice patterns (SP) for KHDRBS3 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b
SP1: - -
SP2: - - -
SP3: -
SP4:

Relevant External Links for KHDRBS3 Gene

GeneLoc Exon Structure for
KHDRBS3
ECgene alternative splicing isoforms for
KHDRBS3

Expression for KHDRBS3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KHDRBS3 Gene

mRNA differential expression in normal tissues according to GTEx for KHDRBS3 Gene

This gene is overexpressed in Testis (x5.1) and Brain - Frontal Cortex (BA9) (x4.2).

Protein differential expression in normal tissues from HIPED for KHDRBS3 Gene

This gene is overexpressed in Fetal Brain (25.3), Retina (7.2), Cervix (7.1), and Breast (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KHDRBS3 Gene



Protein tissue co-expression partners for KHDRBS3 Gene

NURSA nuclear receptor signaling pathways regulating expression of KHDRBS3 Gene:

KHDRBS3

SOURCE GeneReport for Unigene cluster for KHDRBS3 Gene:

Hs.444558

mRNA Expression by UniProt/SwissProt for KHDRBS3 Gene:

O75525-KHDR3_HUMAN
Tissue specificity: Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis.

Evidence on tissue expression from TISSUES for KHDRBS3 Gene

  • Nervous system(4.6)
  • Eye(4.1)
  • Skin(4.1)
  • Liver(2.2)
genes like me logo Genes that share expression patterns with KHDRBS3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for KHDRBS3 Gene

Orthologs for KHDRBS3 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for KHDRBS3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KHDRBS3 34 33
  • 100 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KHDRBS3 34
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KHDRBS3 34 33
  • 92.58 (n)
OneToOne
dog
(Canis familiaris)
Mammalia KHDRBS3 34 33
  • 91.91 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Khdrbs3 33
  • 89.79 (n)
mouse
(Mus musculus)
Mammalia Khdrbs3 16 34 33
  • 89.4 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia KHDRBS3 34
  • 87 (a)
OneToOne
chicken
(Gallus gallus)
Aves KHDRBS3 34 33
  • 82.17 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KHDRBS3 34
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia khdrbs3 33
  • 73.31 (n)
Str.11350 33
zebrafish
(Danio rerio)
Actinopterygii khdrbs3 34 33
  • 67.88 (n)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta qkr58E-1 34 35 33
  • 54.69 (n)
ManyToMany
CG3875 35
  • 46 (a)
CG3927 34 35
  • 35 (a)
ManyToMany
qkr54B 34 35
  • 33 (a)
ManyToMany
qkr58E-3 34 35
  • 33 (a)
ManyToMany
CG4021 34 35
  • 31 (a)
ManyToMany
nsr 34
  • 30 (a)
ManyToMany
qkr58E-2 34 35
  • 28 (a)
ManyToMany
CG10384 34 35
  • 22 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea K07H8.9 34
  • 22 (a)
ManyToMany
Y69A2AR.32 34
  • 22 (a)
ManyToMany
Y57G11C.36 34
  • 22 (a)
ManyToMany
F54D1.1 34
  • 21 (a)
ManyToMany
B0280.17 34
  • 19 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MSL5 34
  • 13 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11338 34
  • 35 (a)
OneToMany
Species where no ortholog for KHDRBS3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KHDRBS3 Gene

ENSEMBL:
Gene Tree for KHDRBS3 (if available)
TreeFam:
Gene Tree for KHDRBS3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KHDRBS3: view image

Paralogs for KHDRBS3 Gene

Paralogs for KHDRBS3 Gene

(3) SIMAP similar genes for KHDRBS3 Gene using alignment to 9 proteins:

  • KHDR3_HUMAN
  • E5RG12_HUMAN
  • E5RHD3_HUMAN
  • E5RJZ9_HUMAN
  • H0YAQ1_HUMAN
  • H0YAQ3_HUMAN
  • H0YB45_HUMAN
  • L8EAJ0_HUMAN
  • L8EC47_HUMAN
genes like me logo Genes that share paralogs with KHDRBS3: view

Variants for KHDRBS3 Gene

Sequence variations from dbSNP and Humsavar for KHDRBS3 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000030751 -- 135,546,959(+) G/T intron_variant
rs1000034639 -- 135,605,833(+) T/C genic_downstream_transcript_variant, intron_variant
rs1000040936 -- 135,656,913(+) G/T downstream_transcript_variant
rs1000045108 -- 135,495,042(+) C/A intron_variant
rs1000046442 -- 135,580,061(+) C/T genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KHDRBS3 Gene

Variant ID Type Subtype PubMed ID
dgv1222e201 CNV deletion 23290073
dgv473e215 CNV deletion 23714750
esv2389682 CNV deletion 18987734
esv2421926 CNV deletion 20811451
esv2663629 CNV deletion 23128226
esv2737635 CNV deletion 23290073
esv2737638 CNV deletion 23290073
esv2737639 CNV deletion 23290073
esv2737641 CNV deletion 23290073
esv2737642 CNV deletion 23290073
esv2737643 CNV deletion 23290073
esv2737644 CNV deletion 23290073
esv2737645 CNV deletion 23290073
esv2761207 CNV loss 21179565
esv29654 CNV loss 19812545
esv29678 CNV loss 19812545
esv3326013 CNV insertion 20981092
esv3618923 CNV loss 21293372
esv7328 CNV gain 19470904
esv7569 CNV gain 19470904
nsv1076114 CNV deletion 25765185
nsv1122203 CNV deletion 24896259
nsv1137404 CNV deletion 24896259
nsv1144236 CNV deletion 24896259
nsv1161806 CNV deletion 26073780
nsv442124 CNV loss 18776908
nsv476150 CNV novel sequence insertion 20440878
nsv515070 CNV loss 21397061
nsv524132 CNV loss 19592680
nsv612336 CNV loss 21841781
nsv612337 CNV loss 21841781
nsv612338 CNV loss 21841781
nsv612339 CNV loss 21841781
nsv6412 CNV insertion 18451855
nsv831469 CNV gain 17160897
nsv971354 CNV duplication 23825009

Variation tolerance for KHDRBS3 Gene

Residual Variation Intolerance Score: 29% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.31; 6.80% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KHDRBS3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KHDRBS3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KHDRBS3 Gene

Disorders for KHDRBS3 Gene

MalaCards: The human disease database

(6) MalaCards diseases for KHDRBS3 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
transvestism
  • cross dresser
fetishism
childhood absence epilepsy
  • absence seizure
extratemporal epilepsy
hypophosphatasia, adult
  • hypophosphatasia, mild
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for KHDRBS3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with KHDRBS3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for KHDRBS3 Gene

Publications for KHDRBS3 Gene

  1. Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor. (PMID: 15901763) Cohen CD … Kretzler M (Journal of the American Society of Nephrology : JASN 2005) 3 4 22 58
  2. A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication. (PMID: 11741900) Reddy TR … Wong-Staal F (The Journal of biological chemistry 2002) 3 4 22 58
  3. Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis. (PMID: 10077576) Di Fruscio M … Richard S (Proceedings of the National Academy of Sciences of the United States of America 1999) 3 4 22 58
  4. T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis. (PMID: 10332027) Venables JP … Eperon IC (Human molecular genetics 1999) 2 3 4 58
  5. Salpalpha and Salpbeta, growth-arresting homologs of Sam68. (PMID: 10564820) Lee J … Burr JG (Gene 1999) 2 3 4 58

Products for KHDRBS3 Gene

Sources for KHDRBS3 Gene

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