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The ZXDB gene is one of a pair of duplicated zinc finger genes on chromosome Xp11.21 (Greig et al., 1993 [PubMed 8268913]); see also ZXDA (MIM 300235).[supplied by OMIM, Jul 2010]
ZXDB (Zinc Finger X-Linked Duplicated B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZXDA.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH0XJ057590 | Promoter/Enhancer | 1.5 | Ensembl ENCODE CraniofacialAtlas | 0.7 | +2.3 | 2316 | 6.5 | PRDM10 ZNF629 ZNF692 BACH1 LARP7 ZIC2 RBFOX2 PKNOX1 TCF12 CTCF | MTHFD1P1 ZXDB lnc-NLRP2B-1 NLRP2B | |
GH0XJ058103 | Enhancer | 0.2 | dbSUPER | 4.1 | +514.3 | 514312 | 5.2 | SPIN2B FAAH2 ZXDB piR-61240-317 piR-61240-316 ZXDA | ||
GH0XJ057644 | Enhancer | 0.7 | Ensembl | 0.2 | +52.4 | 52448 | 0.2 | GATAD2A RXRB SOX13 SP1 FOXA1 FOXA2 NR3C1 TEAD1 JUND CREM | lnc-ZXDB-1 LOC107985708 NLRP2B ZXDB | |
GH0XJ057285 | Promoter/Enhancer | 1.5 | EPDnew Ensembl ENCODE | 0.1 | -305.0 | -304966 | 3 | CREB1 GATAD2A PRDM10 ZNF629 RCOR2 ZHX2 FOXA1 PRDM1 ZNF143 ZNF24 | FAAH2 MTHFD1P1 piR-57133-642 piR-60885-174 SPIN2A ZXDB | |
GH0XJ057335 | Enhancer | 0.8 | Ensembl ENCODE | 0.1 | -255.8 | -255764 | 1.6 | CREB1 GATAD2A SOX13 CTBP1 FOXA2 ZNF217 FOXA1 FOSL2 NFIL3 RARA | MTHFD1P1 SPIN2B NBDY piR-50968-142 SPIN2A FAAH2 ZXDB |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0003676 | nucleic acid binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008150 | biological_process | ND | -- |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZXDB 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ZXDB 30 |
|
||
-- 31 |
|
OneToMany | |||
Cow (Bos Taurus) |
Mammalia | LOC510362 30 |
|
||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Mouse (Mus musculus) |
Mammalia | Zxdb 30 17 31 |
|
OneToMany | |
Rat (Rattus norvegicus) |
Mammalia | Zxdb 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Zebrafish (Danio rerio) |
Actinopterygii | ZXDC 31 |
|
OneToMany | |
Fruit Fly (Drosophila melanogaster) |
Insecta | CG9609 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SWI5 31 |
|
ManyToMany | |
ACE2 31 |
|
ManyToMany |
No disorders were found for ZXDB Gene.