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Aliases for ZSWIM9 Gene

Aliases for ZSWIM9 Gene

  • Zinc Finger SWIM-Type Containing 9 2 3 5
  • C19orf68 3 4
  • Chromosome 19 Open Reading Frame 68 2
  • Uncharacterized Protein C19orf68 3
  • Uncharacterized Protein ZSWIM9 3

External Ids for ZSWIM9 Gene

Previous HGNC Symbols for ZSWIM9 Gene

  • C19orf68

Summaries for ZSWIM9 Gene

GeneCards Summary for ZSWIM9 Gene

ZSWIM9 (Zinc Finger SWIM-Type Containing 9) is a Protein Coding gene.

Additional gene information for ZSWIM9 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSWIM9 Gene

Genomics for ZSWIM9 Gene

GeneHancer (GH) Regulatory Elements for ZSWIM9 Gene

Promoters and enhancers for ZSWIM9 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J048168 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 650.7 -0.2 -155 3.1 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF766 LIG1 ZSWIM9 BICRA KDELR1 GRWD1 CCDC9 PLA2G4C NOP53 NOP53-AS1 RPL18
GH19J048958 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 12.7 +793.4 793367 10.2 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF263 FTL ENSG00000267898 GC19P048967 GC19P048966 NUP62 PTOV1-AS2 IRF3 SNORD35A SNORD35B PRR12
GH19J047225 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 12.7 -941.3 -941281 8.2 MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF416 ZNF143 BBC3 BICRA ENSG00000268810 NOP53-AS1 CCDC9 NOP53 ENSG00000269321 SNORD23 PPP5D1 INAFM1
GH19J047741 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 12.7 -426.7 -426741 5 CLOCK MLX ZFP64 DMAP1 YY1 SLC30A9 E2F8 ZNF416 ZNF143 ZNF548 NOP53 ZC3H4 BICRA ENSG00000269321 SELENOW GRWD1 RASIP1 BSPH1 CA11 TPRX2P
GH19J048328 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 12.8 +161.0 161004 5.8 HDGF PKNOX1 SMAD1 ARNT SIN3A FEZF1 YBX1 ZNF2 YY1 POLR2B BICRA GRWD1 TMEM143 SNRNP70 NOP53-AS1 CA11 NOP53 KDELR1 RPL18 ZSWIM9
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZSWIM9 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZSWIM9 Gene

Genomic Locations for ZSWIM9 Gene
chr19:48,170,662-48,197,621
(GRCh38/hg38)
Size:
26,960 bases
Orientation:
Plus strand
chr19:48,673,949-48,700,877
(GRCh37/hg19)
Size:
26,929 bases
Orientation:
Plus strand

Genomic View for ZSWIM9 Gene

Genes around ZSWIM9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSWIM9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSWIM9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSWIM9 Gene

Proteins for ZSWIM9 Gene

  • Protein details for ZSWIM9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86XI8-ZSWM9_HUMAN
    Recommended name:
    Uncharacterized protein ZSWIM9
    Protein Accession:
    Q86XI8
    Secondary Accessions:
    • A0A087WWL5

    Protein attributes for ZSWIM9 Gene

    Size:
    627 amino acids
    Molecular mass:
    70073 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH43386.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSWIM9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSWIM9 Gene

Post-translational modifications for ZSWIM9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSWIM9 Gene

No data available for DME Specific Peptides for ZSWIM9 Gene

Domains & Families for ZSWIM9 Gene

Gene Families for ZSWIM9 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZSWIM9 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZSWIM9: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ZSWIM9 Gene

Function for ZSWIM9 Gene

Phenotypes From GWAS Catalog for ZSWIM9 Gene

Gene Ontology (GO) - Molecular Function for ZSWIM9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZSWIM9: view
genes like me logo Genes that share phenotypes with ZSWIM9: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSWIM9 Gene

Localization for ZSWIM9 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSWIM9 gene
Compartment Confidence
nucleus 3
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZSWIM9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSWIM9: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZSWIM9 Gene

Pathways & Interactions for ZSWIM9 Gene

SuperPathways for ZSWIM9 Gene

No Data Available

Interacting Proteins for ZSWIM9 Gene

Gene Ontology (GO) - Biological Process for ZSWIM9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006511 ubiquitin-dependent protein catabolic process IEA --
GO:0007275 multicellular organism development IEA --
genes like me logo Genes that share ontologies with ZSWIM9: view

No data available for Pathways by source and SIGNOR curated interactions for ZSWIM9 Gene

Drugs & Compounds for ZSWIM9 Gene

No Compound Related Data Available

Transcripts for ZSWIM9 Gene

mRNA/cDNA for ZSWIM9 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM9 Gene

No ASD Table

Relevant External Links for ZSWIM9 Gene

GeneLoc Exon Structure for
ZSWIM9
ECgene alternative splicing isoforms for
ZSWIM9

Expression for ZSWIM9 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZSWIM9 Gene:

ZSWIM9

Evidence on tissue expression from TISSUES for ZSWIM9 Gene

  • Eye(4)
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSWIM9 Gene

Orthologs for ZSWIM9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSWIM9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf68 33
  • 97.96 (n)
C19orf68 34
  • 86 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19orf68 34
  • 89 (a)
OneToOne
C18H19orf68 33
  • 86.4 (n)
dog
(Canis familiaris)
Mammalia C1H19orf68 33
  • 86.9 (n)
C19orf68 34
  • 59 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 6330408A02Rik 34 33
  • 76.95 (n)
OneToOne
Zswim9 16
rat
(Rattus norvegicus)
Mammalia RGD1310257 33
  • 76 (n)
oppossum
(Monodelphis domestica)
Mammalia C19orf68 34
  • 48 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C19orf68 34
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C19orf68 34
  • 34 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia 6330408a02rik 33
  • 50.07 (n)
Species where no ortholog for ZSWIM9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSWIM9 Gene

ENSEMBL:
Gene Tree for ZSWIM9 (if available)
TreeFam:
Gene Tree for ZSWIM9 (if available)

Paralogs for ZSWIM9 Gene

No data available for Paralogs for ZSWIM9 Gene

Variants for ZSWIM9 Gene

Sequence variations from dbSNP and Humsavar for ZSWIM9 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000004962 -- 48,182,503(+) G/A coding_sequence_variant, genic_upstream_transcript_variant, synonymous_variant
rs1000013643 -- 48,183,367(+) T/C genic_upstream_transcript_variant, intron_variant
rs1000025107 -- 48,179,141(+) TTTTTTTTT/TTTTTTTTTT genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000048604 -- 48,171,696(+) G/T genic_upstream_transcript_variant, intron_variant
rs1000071585 -- 48,183,489(+) G/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZSWIM9 Gene

Variant ID Type Subtype PubMed ID
esv1261804 CNV insertion 17803354
esv34181 CNV loss 18971310
nsv525109 CNV loss 19592680
nsv833853 CNV loss 17160897
nsv953597 CNV deletion 24416366
nsv9739 CNV gain+loss 18304495

Variation tolerance for ZSWIM9 Gene

Gene Damage Index Score: 0.82; 17.21% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSWIM9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSWIM9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSWIM9 Gene

Disorders for ZSWIM9 Gene

No disorders were found for ZSWIM9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSWIM9 Gene

Publications for ZSWIM9 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
  4. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E … Yanagawa H (PloS one 2010) 3 58
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 58

Products for ZSWIM9 Gene

Sources for ZSWIM9 Gene

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