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Aliases for ZSCAN9 Gene

Aliases for ZSCAN9 Gene

  • Zinc Finger And SCAN Domain Containing 9 2 3 5
  • Zinc Finger Protein 193 2 3 4
  • Cell Proliferation-Inducing Gene 12 Protein 3 4
  • ZNF193 3 4
  • PRD51 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 9 3
  • Cell Proliferation-Inducing Protein 12 3

External Ids for ZSCAN9 Gene

Previous HGNC Symbols for ZSCAN9 Gene

  • ZNF193

Previous GeneCards Identifiers for ZSCAN9 Gene

  • GC06P028192
  • GC06P028224

Summaries for ZSCAN9 Gene

GeneCards Summary for ZSCAN9 Gene

ZSCAN9 (Zinc Finger And SCAN Domain Containing 9) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZKSCAN8.

UniProtKB/Swiss-Prot for ZSCAN9 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZSCAN9 Gene

Additional gene information for ZSCAN9 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN9 Gene

Genomics for ZSCAN9 Gene

GeneHancer (GH) Regulatory Elements for ZSCAN9 Gene

Promoters and enhancers for ZSCAN9 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I028224 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 570.2 +12.7 12664 2.1 MLX ZFP64 DMAP1 IRF4 YY1 E2F8 ZNF143 SP3 MEF2D SSRP1 ZSCAN9 ZNF603P ZKSCAN4 ZKSCAN3 ZKSCAN8 ZNF192P1 NKAPL ZSCAN12 ZSCAN31 TRIM27
GH06I028211 Enhancer 1.3 Ensembl ENCODE 574.5 -0.1 -131 2.2 FEZF1 IRF4 SLC30A9 ZNF213 E2F8 ZNF143 SP3 MEF2D SSRP1 ZNF610 ZSCAN9 GC06P028271 TRS-GCT5-1 ZKSCAN8 ZNF603P ZSCAN12 ZKSCAN3 PGBD1 ZSCAN23 ZSCAN31
GH06I027834 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 54.3 -375.4 -375372 6.4 CLOCK FEZF1 DMAP1 IRF4 YY1 SLC30A9 E2F8 SP3 NFYC MEF2D HIST1H2BN HIST1H2AK GC06M027849 ZKSCAN3 ZKSCAN8 ZKSCAN4 ZSCAN9 ZSCAN12 HIST1H3J GUSBP2
GH06I027887 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 50.5 -319.2 -319184 11.9 ZFP64 DMAP1 IRF4 YY1 E2F8 ZNF143 NFYC SSRP1 ZNF610 RCOR2 HIST1H2AM HIST1H2BO HIST1H3J GC06M028114 PIR45952 PIR61297 PIR62073 PIR50251 ZKSCAN8 ZKSCAN3
GH06I027494 Enhancer 1.3 Ensembl ENCODE 81.8 -717.0 -717016 1.7 FEZF1 ZNF213 E2F8 ZNF143 SP3 ZFP41 MEF2D SSRP1 ZNF610 RCOR2 TRS-AGA2-3 ZSCAN12 ZSCAN23 ZKSCAN8 PGBD1 ZNF322 ZKSCAN3 ZSCAN9 ZNF391 ENSG00000261839
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZSCAN9 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZSCAN9 Gene

Genomic Locations for ZSCAN9 Gene
chr6:28,212,665-28,233,487
(GRCh38/hg38)
Size:
20,823 bases
Orientation:
Plus strand
chr6:28,192,664-28,201,265
(GRCh37/hg19)

Genomic View for ZSCAN9 Gene

Genes around ZSCAN9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN9 Gene

Proteins for ZSCAN9 Gene

  • Protein details for ZSCAN9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15535-ZSC9_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 9
    Protein Accession:
    O15535
    Secondary Accessions:
    • B4E1W6
    • E7EVQ2
    • Q2TTR1

    Protein attributes for ZSCAN9 Gene

    Size:
    394 amino acids
    Molecular mass:
    45954 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN9 Gene

Post-translational modifications for ZSCAN9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN9 Gene

Domains & Families for ZSCAN9 Gene

Gene Families for ZSCAN9 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZSCAN9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O15535

UniProtKB/Swiss-Prot:

ZSC9_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZSCAN9: view

Function for ZSCAN9 Gene

Molecular function for ZSCAN9 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZSCAN9 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN9: view
genes like me logo Genes that share phenotypes with ZSCAN9: view

Animal Model Products

CRISPR Products

miRNA for ZSCAN9 Gene

miRTarBase miRNAs that target ZSCAN9

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN9 Gene

Localization for ZSCAN9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN9 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN9 gene
Compartment Confidence
nucleus 5
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZSCAN9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSCAN9: view

Pathways & Interactions for ZSCAN9 Gene

SuperPathways for ZSCAN9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN9: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN9 Gene

Drugs & Compounds for ZSCAN9 Gene

No Compound Related Data Available

Transcripts for ZSCAN9 Gene

Unigene Clusters for ZSCAN9 Gene

Zinc finger and SCAN domain containing 9:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN9 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b · 5c
SP1: - - - - -
SP2: - - - -
SP3: -
SP4: -
SP5: - - -
SP6: - -

Relevant External Links for ZSCAN9 Gene

GeneLoc Exon Structure for
ZSCAN9
ECgene alternative splicing isoforms for
ZSCAN9

Expression for ZSCAN9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN9 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN9 Gene:

ZSCAN9

SOURCE GeneReport for Unigene cluster for ZSCAN9 Gene:

Hs.100921

Evidence on tissue expression from TISSUES for ZSCAN9 Gene

  • Intestine(4.2)
  • Bone marrow(4.1)
genes like me logo Genes that share expression patterns with ZSCAN9: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN9 Gene

Orthologs for ZSCAN9 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF193 33 34
  • 99.48 (n)
cow
(Bos Taurus)
Mammalia ZSCAN9 34
  • 78 (a)
OneToOne
Species where no ortholog for ZSCAN9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN9 Gene

ENSEMBL:
Gene Tree for ZSCAN9 (if available)
TreeFam:
Gene Tree for ZSCAN9 (if available)

Paralogs for ZSCAN9 Gene

(429) SIMAP similar genes for ZSCAN9 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZSCAN9: view

Variants for ZSCAN9 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN9 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000335920 -- 28,232,972(+) C/T coding_sequence_variant, stop_gained
rs1000483708 -- 28,226,537(+) A/G intron_variant
rs1000572502 -- 28,226,889(+) C/T intron_variant
rs1001230493 -- 28,228,365(+) G/A intron_variant
rs1001317540 -- 28,223,199(+) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN9 Gene

Variant ID Type Subtype PubMed ID
nsv830620 CNV loss 17160897

Variation tolerance for ZSCAN9 Gene

Residual Variation Intolerance Score: 68.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.34; 53.63% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSCAN9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN9 Gene

Disorders for ZSCAN9 Gene

Additional Disease Information for ZSCAN9

No disorders were found for ZSCAN9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN9 Gene

Publications for ZSCAN9 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
  3. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. (PMID: 9244436) Lee PL … Beutler E (Genomics 1997) 3 4 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for ZSCAN9 Gene

Sources for ZSCAN9 Gene

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