Aliases for ZSCAN5C Gene

Aliases for ZSCAN5C Gene

  • Zinc Finger And SCAN Domain Containing 5C 2 3 5
  • Zinc Finger And SCAN Domain-Containing Protein 5C Pseudogene 3 4
  • Zinc Finger And SCAN Domain Containing 5C, Pseudogene 2 3
  • Zinc Finger And SCAN Domain-Containing Protein 5C 3 4
  • ZSCAN5CP 3 4
  • ZNF495C 2 3
  • Zinc Finger And SCAN Domain-Containing Protein 5-Like Protein 2 3
  • Putative Zinc Finger And SCAN Domain-Containing Protein 5C 3
  • ZSCAN5C 5

External Ids for ZSCAN5C Gene

Previous HGNC Symbols for ZSCAN5C Gene

  • ZSCAN5CP

Previous GeneCards Identifiers for ZSCAN5C Gene

  • GC19P061411
  • GC19P056717
  • GC19P053026

Summaries for ZSCAN5C Gene

GeneCards Summary for ZSCAN5C Gene

ZSCAN5C (Zinc Finger And SCAN Domain Containing 5C) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity, RNA polymerase II-specific. An important paralog of this gene is ZSCAN5A.

UniProtKB/Swiss-Prot Summary for ZSCAN5C Gene

Additional gene information for ZSCAN5C Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZSCAN5C Gene

Genomics for ZSCAN5C Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZSCAN5C Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J056228 Promoter 0.3 EPDnew 11.4 +26.0 26020 0.1 ZSCAN5A ZSCAN5C ZNF444 RPL13P13 piR-51288-002 EDDM13
GH19J056216 Promoter/Enhancer 1 Ensembl ENCODE CraniofacialAtlas 0.4 +15.1 15100 1.2 TAF1 EZH2 ENSG00000242411 RPL13P13 ZNF264 HSALNG0127738 ZSCAN5C EDDM13
GH19J056252 Enhancer 1 Ensembl ENCODE 0.2 +51.1 51124 1.6 CTCF ZNF512 ZHX2 JUND ZNF143 PHF21A ZNF24 REST RAD21 ZNF740 SSC5D ENSG00000267523 U2AF2 ZNF264 ZNF444 ZNF805 RF00017-3087 ZSCAN5DP EDDM13 ZSCAN5C
GH19J056270 Enhancer 0.8 Ensembl ENCODE 0.2 +69.1 69100 6.8 FOSL1 ZNF623 NFIC ZNF395 SPI1 TAL1 VEZF1 PRDM10 JUN POLR2A EDDM13 lnc-EDDM13-1 ZNF582-AS1 ENSG00000267689 lnc-ZSCAN5B-2 lnc-ZNF582-5 ZSCAN5C ZSCAN5A
GH19J056263 Enhancer 0.6 Ensembl 0.2 +61.7 61700 1.6 IKZF1 DPF2 HDAC1 SOX6 TCF12 EP300 NCOR1 TAL1 HDAC2 KDM1A lnc-ZSCAN5B-2 EDDM13 RF00017-3087 lnc-ZNF582-5 ZSCAN5C ZSCAN5A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZSCAN5C on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZSCAN5C

Top Transcription factor binding sites by QIAGEN in the ZSCAN5C gene promoter:
  • AREB6
  • NF-kappaB
  • NF-kappaB1
  • POU2F1
  • POU2F1a
  • SRF
  • SRF (504 AA)

Genomic Locations for ZSCAN5C Gene

Genomic Locations for ZSCAN5C Gene
chr19:56,202,301-56,209,452
(GRCh38/hg38)
Size:
7,152 bases
Orientation:
Plus strand
chr19:56,713,670-56,720,823
(GRCh37/hg19)
Size:
7,154 bases
Orientation:
Plus strand

Genomic View for ZSCAN5C Gene

Genes around ZSCAN5C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN5C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN5C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN5C Gene

Proteins for ZSCAN5C Gene

  • Protein details for ZSCAN5C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGD5-ZSA5C_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 5C
    Protein Accession:
    A6NGD5

    Protein attributes for ZSCAN5C Gene

    Size:
    496 amino acids
    Molecular mass:
    55729 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZSCAN5C Gene

Post-translational modifications for ZSCAN5C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN5C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSCAN5C Gene

Domains & Families for ZSCAN5C Gene

Gene Families for ZSCAN5C Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZSCAN5C Gene

Suggested Antigen Peptide Sequences for ZSCAN5C Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger and SCAN domain-containing protein 5C (ZSA5C_HUMAN)
genes like me logo Genes that share domains with ZSCAN5C: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ZSCAN5C Gene

Function for ZSCAN5C Gene

Molecular function for ZSCAN5C Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZSCAN5C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003700 DNA-binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN5C: view

Phenotypes for ZSCAN5C Gene

genes like me logo Genes that share phenotypes with ZSCAN5C: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZSCAN5C

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN5C Gene

Localization for ZSCAN5C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN5C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN5C gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear speckles (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZSCAN5C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSCAN5C: view

Pathways & Interactions for ZSCAN5C Gene

PathCards logo

SuperPathways for ZSCAN5C Gene

No Data Available

Interacting Proteins for ZSCAN5C Gene

Gene Ontology (GO) - Biological Process for ZSCAN5C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN5C: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN5C Gene

Drugs & Compounds for ZSCAN5C Gene

No Compound Related Data Available

Transcripts for ZSCAN5C Gene

mRNA/cDNA for ZSCAN5C Gene

1 REFSEQ mRNAs :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZSCAN5C

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN5C Gene

No ASD Table

Relevant External Links for ZSCAN5C Gene

GeneLoc Exon Structure for
ZSCAN5C

Expression for ZSCAN5C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZSCAN5C Gene

mRNA differential expression in normal tissues according to GTEx for ZSCAN5C Gene

This gene is overexpressed in Testis (x5.9).
genes like me logo Genes that share expression patterns with ZSCAN5C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN5C Gene

Orthologs for ZSCAN5C Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN5C Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZSCAN5C 31
  • 98 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia -- 31
  • 47 (a)
ManyToMany
-- 31
  • 45 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 41 (a)
ManyToMany
-- 31
  • 40 (a)
ManyToMany
-- 31
  • 40 (a)
ManyToMany
Mouse
(Mus musculus)
Mammalia Zscan5b 31
  • 39 (a)
OneToMany
Species where no ortholog for ZSCAN5C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZSCAN5C Gene

ENSEMBL:
Gene Tree for ZSCAN5C (if available)
TreeFam:
Gene Tree for ZSCAN5C (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZSCAN5C: view image

Paralogs for ZSCAN5C Gene

(22) SIMAP similar genes for ZSCAN5C Gene using alignment to 1 proteins:

  • ZSA5C_HUMAN

Pseudogenes.org Pseudogenes for ZSCAN5C Gene

genes like me logo Genes that share paralogs with ZSCAN5C: view

Variants for ZSCAN5C Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZSCAN5C Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs10419548 - p.Gln24Arg
rs12979551 - p.Glu197Asp
rs1865102 - p.Gln259Lys
rs4801690 - p.Gln181Arg

Additional dbSNP identifiers (rs#s) for ZSCAN5C Gene

Variation tolerance for ZSCAN5C Gene

Gene Damage Index Score: 6.16; 75.78% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSCAN5C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN5C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZSCAN5C Gene

Disorders for ZSCAN5C Gene

No disorders were found for ZSCAN5C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN5C Gene

Publications for ZSCAN5C Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4

Products for ZSCAN5C Gene

Sources for ZSCAN5C Gene