Aliases for ZSCAN30 Gene

Aliases for ZSCAN30 Gene

  • Zinc Finger And SCAN Domain Containing 30 2 3 5
  • Zinc Finger Protein 397 Opposite Strand 2 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 30 3 4
  • Zinc Finger Protein 397OS 3 4
  • ZNF397 Opposite Strand 2 3
  • ZNF397OS 3 4
  • ZNF-WYM 3 4
  • ZNF917 3

External Ids for ZSCAN30 Gene

Previous HGNC Symbols for ZSCAN30 Gene

  • ZNF397OS

Previous GeneCards Identifiers for ZSCAN30 Gene

  • GC18M032833
  • GC18M029690

Summaries for ZSCAN30 Gene

GeneCards Summary for ZSCAN30 Gene

ZSCAN30 (Zinc Finger And SCAN Domain Containing 30) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is ZSCAN12.

UniProtKB/Swiss-Prot Summary for ZSCAN30 Gene

Additional gene information for ZSCAN30 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZSCAN30 Gene

Genomics for ZSCAN30 Gene

GeneHancer (GH) Regulatory Elements for ZSCAN30 Gene

Promoters and enhancers for ZSCAN30 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZSCAN30 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZSCAN30

Genomic Locations for ZSCAN30 Gene

Genomic Locations for ZSCAN30 Gene
39,202 bases
Minus strand
39,174 bases
Minus strand

Genomic View for ZSCAN30 Gene

Genes around ZSCAN30 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN30 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN30 Gene

Proteins for ZSCAN30 Gene

  • Protein details for ZSCAN30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger and SCAN domain-containing protein 30
    Protein Accession:
    Secondary Accessions:
    • B4E0N0
    • Q6ZNB3
    • Q96PN3

    Protein attributes for ZSCAN30 Gene

    494 amino acids
    Molecular mass:
    56364 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAL26786.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSCAN30 Gene


neXtProt entry for ZSCAN30 Gene

Post-translational modifications for ZSCAN30 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN30 Gene

Domains & Families for ZSCAN30 Gene

Gene Families for ZSCAN30 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZSCAN30 Gene

  • Transcriptional regulator SCAN

Suggested Antigen Peptide Sequences for ZSCAN30 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 397OS (ZSC30_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZSCAN30: view

Function for ZSCAN30 Gene

Molecular function for ZSCAN30 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZSCAN30 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA-binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN30: view
genes like me logo Genes that share phenotypes with ZSCAN30: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN30 Gene

Localization for ZSCAN30 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN30 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN30 gene
Compartment Confidence
nucleus 4
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZSCAN30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSCAN30: view

Pathways & Interactions for ZSCAN30 Gene

PathCards logo

SuperPathways for ZSCAN30 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN30: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN30 Gene

Drugs & Compounds for ZSCAN30 Gene

No Compound Related Data Available

Transcripts for ZSCAN30 Gene

mRNA/cDNA for ZSCAN30 Gene

14 NCBI additional mRNA sequence :
12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN30 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b
SP1: - -
SP2: -
SP3: -

Relevant External Links for ZSCAN30 Gene

GeneLoc Exon Structure for

Expression for ZSCAN30 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZSCAN30 Gene

Protein differential expression in normal tissues from HIPED for ZSCAN30 Gene

This gene is overexpressed in Adipocyte (39.0) and Spinal cord (30.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZSCAN30 Gene

Protein tissue co-expression partners for ZSCAN30 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZSCAN30

SOURCE GeneReport for Unigene cluster for ZSCAN30 Gene:

genes like me logo Genes that share expression patterns with ZSCAN30: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN30 Gene

Orthologs for ZSCAN30 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN30 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZSCAN30 31 30
  • 99.66 (n)
(Canis familiaris)
Mammalia ZSCAN30 31 30
  • 84.93 (n)
(Bos Taurus)
Mammalia ZSCAN30 30
  • 83.2 (n)
(Mus musculus)
Mammalia Zscan30 17 31 30
  • 74.69 (n)
(Rattus norvegicus)
Mammalia Zscan30 30
  • 73.4 (n)
(Monodelphis domestica)
Mammalia ZSCAN30 31
  • 56 (a)
Species where no ortholog for ZSCAN30 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN30 Gene

Gene Tree for ZSCAN30 (if available)
Gene Tree for ZSCAN30 (if available)
Evolutionary constrained regions (ECRs) for ZSCAN30: view image

Paralogs for ZSCAN30 Gene

(474) SIMAP similar genes for ZSCAN30 Gene using alignment to 7 proteins:

  • M0R1Y0_HUMAN Pseudogenes for ZSCAN30 Gene

genes like me logo Genes that share paralogs with ZSCAN30: view

Variants for ZSCAN30 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZSCAN30 Gene

SNP ID Clinical significance and condition Chr 18 pos Variation AA Info Type
rs2249769 - p.Gln238Pro

Additional dbSNP identifiers (rs#s) for ZSCAN30 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN30 Gene

Variant ID Type Subtype PubMed ID
esv3305949 CNV mobile element insertion 20981092
esv3390534 CNV insertion 20981092
esv3642197 CNV gain 21293372
nsv1059793 CNV gain 25217958

Variation tolerance for ZSCAN30 Gene

Residual Variation Intolerance Score: 66.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.57; 72.25% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSCAN30 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN30 Gene

Disorders for ZSCAN30 Gene

Additional Disease Information for ZSCAN30

No disorders were found for ZSCAN30 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN30 Gene

Publications for ZSCAN30 Gene

  1. Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397. (PMID: 12801647) Wu Y … Zhao S (Gene 2003) 2 3 4 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 54
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 54

Products for ZSCAN30 Gene

Sources for ZSCAN30 Gene