Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZSCAN26 Gene

Aliases for ZSCAN26 Gene

  • Zinc Finger And SCAN Domain Containing 26 2 3 5
  • Zinc Finger Protein 187 2 3 4
  • ZNF187 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 26 3
  • Protein SRE-ZBP 4
  • SRE-ZBP 3
  • SREZBP 3

External Ids for ZSCAN26 Gene

Previous HGNC Symbols for ZSCAN26 Gene

  • ZNF187

Previous GeneCards Identifiers for ZSCAN26 Gene

  • GC06P028235
  • GC06P028268

Summaries for ZSCAN26 Gene

GeneCards Summary for ZSCAN26 Gene

ZSCAN26 (Zinc Finger And SCAN Domain Containing 26) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZKSCAN8.

UniProtKB/Swiss-Prot for ZSCAN26 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZSCAN26 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN26 Gene

Genomics for ZSCAN26 Gene

GeneHancer (GH) Regulatory Elements for ZSCAN26 Gene

Promoters and enhancers for ZSCAN26 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I028266 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 +0.5 476 2.4 HDGF SMAD1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ENSG00000276302 ZSCAN26 ZSCAN12 ZKSCAN3 ZKSCAN8 ZSCAN31 ZKSCAN4 ZNF603P PGBD1 ZNF391
GH06I028079 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 28.4 -186.3 -186344 3.1 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF165 LOC102724889 ZNF603P ZKSCAN8 ZKSCAN3 ZSCAN12 ZSCAN9 ZKSCAN4 PGBD1 OR2B8P
GH06I028939 Enhancer 1.5 Ensembl ENCODE dbSUPER 37.6 +674.0 674024 3.1 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 SP3 SSRP1 ZNF610 GC06P028942 TRL-CAA1-2 TRQ-CTG1-3 ZSCAN23 ZSCAN12 ZKSCAN8 ZSCAN26 PGBD1 TRIM27 ZKSCAN3
GH06I028789 Enhancer 1.5 Ensembl ENCODE dbSUPER 37.6 +523.2 523174 1.8 PKNOX1 ARNT ARID4B ZNF2 ZNF766 ZNF213 E2F8 FOS SP3 NFYC GC06M028797 TRF-GAA1-1 TRA-TGC1-1 ZSCAN23 ZSCAN12 ZKSCAN4 ZSCAN26 PGBD1 ZKSCAN8 ENSG00000261839
GH06I027591 Enhancer 1.3 Ensembl ENCODE 41.3 -674.1 -674111 2.6 MLX FEZF1 IRF4 SLC30A9 ZNF213 E2F8 ZNF143 SP3 MEF2D SSRP1 GC06M027603 TRK-TTT4-1 TRX-CAT1-6 ZSCAN12 ZSCAN23 ZSCAN26 PGBD1 ZKSCAN8 ZKSCAN3 ZNF322
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZSCAN26 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZSCAN26 Gene

Genomic Locations for ZSCAN26 Gene
chr6:28,267,010-28,278,224
(GRCh38/hg38)
Size:
11,215 bases
Orientation:
Plus strand
chr6:28,234,788-28,245,981
(GRCh37/hg19)

Genomic View for ZSCAN26 Gene

Genes around ZSCAN26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN26 Gene

Proteins for ZSCAN26 Gene

  • Protein details for ZSCAN26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16670-ZSC26_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 26
    Protein Accession:
    Q16670
    Secondary Accessions:
    • Q5JPG4
    • Q7Z3Q6
    • Q96A17

    Protein attributes for ZSCAN26 Gene

    Size:
    478 amino acids
    Molecular mass:
    55254 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAD97775.1; Type=Frameshift; Positions=155, 353; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSCAN26 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN26 Gene

Post-translational modifications for ZSCAN26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN26 Gene

Domains & Families for ZSCAN26 Gene

Gene Families for ZSCAN26 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZSCAN26 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZSCAN26: view

No data available for UniProtKB/Swiss-Prot for ZSCAN26 Gene

Function for ZSCAN26 Gene

Molecular function for ZSCAN26 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
UniProtKB/Swiss-Prot Induction:
By serum stimulation.

Phenotypes From GWAS Catalog for ZSCAN26 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003700 DNA binding transcription factor activity IEA,NAS 1569959
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN26: view
genes like me logo Genes that share phenotypes with ZSCAN26: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN26 Gene

Localization for ZSCAN26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN26 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleus (4)
  • Nucleoli (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,NAS 1569959
GO:0005654 nucleoplasm IDA --
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with ZSCAN26: view

No data available for Subcellular locations from COMPARTMENTS for ZSCAN26 Gene

Pathways & Interactions for ZSCAN26 Gene

SuperPathways for ZSCAN26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS,IEA 1569959
genes like me logo Genes that share ontologies with ZSCAN26: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN26 Gene

Drugs & Compounds for ZSCAN26 Gene

No Compound Related Data Available

Transcripts for ZSCAN26 Gene

Unigene Clusters for ZSCAN26 Gene

Zinc finger and SCAN domain containing 26:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN26 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b · 8c · 8d · 8e · 8f ·
SP1: - - - -
SP2: - - - - - - - -
SP3: - - -
SP4: - - -
SP5: - - - - - - -
SP6: - -
SP7: -
SP8: - - -
SP9: -
SP10: -
SP11: - - - - - - - - - - - - - - -
SP12: - - -
SP13:

ExUns: 8g
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for ZSCAN26 Gene

GeneLoc Exon Structure for
ZSCAN26
ECgene alternative splicing isoforms for
ZSCAN26

Expression for ZSCAN26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN26 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZSCAN26 Gene

This gene is overexpressed in CD8 Tcells (47.6), Blymphocyte (11.7), and Ovary (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZSCAN26 Gene



Protein tissue co-expression partners for ZSCAN26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN26 Gene:

ZSCAN26

SOURCE GeneReport for Unigene cluster for ZSCAN26 Gene:

Hs.157883
genes like me logo Genes that share expression patterns with ZSCAN26: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN26 Gene

Orthologs for ZSCAN26 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF187 33
  • 99.58 (n)
cow
(Bos Taurus)
Mammalia ZSCAN26 33
  • 85.73 (n)
dog
(Canis familiaris)
Mammalia ZSCAN26 33
  • 83.44 (n)
rat
(Rattus norvegicus)
Mammalia Zfp187 33
  • 79.9 (n)
mouse
(Mus musculus)
Mammalia Zscan26 33 16
  • 78.57 (n)
Species where no ortholog for ZSCAN26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN26 Gene

ENSEMBL:
Gene Tree for ZSCAN26 (if available)
TreeFam:
Gene Tree for ZSCAN26 (if available)

Paralogs for ZSCAN26 Gene

(446) SIMAP similar genes for ZSCAN26 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZSCAN26: view

Variants for ZSCAN26 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN26 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000041417 -- 28,271,488(+) A/C intron_variant
rs1000139158 -- 28,278,264(+) A/G downstream_transcript_variant
rs1000293759 -- 28,270,239(+) T/C intron_variant
rs1000407622 -- 28,277,956(+) A/G 3_prime_UTR_variant
rs1001041105 -- 28,273,241(+) C/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN26 Gene

Variant ID Type Subtype PubMed ID
nsv830620 CNV loss 17160897
nsv950146 CNV duplication 24416366

Additional Variant Information for ZSCAN26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZSCAN26 Gene

Disorders for ZSCAN26 Gene

Additional Disease Information for ZSCAN26

No disorders were found for ZSCAN26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN26 Gene

Publications for ZSCAN26 Gene

  1. Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. (PMID: 1569959) Attar RM … Gilman MZ (Molecular and cellular biology 1992) 2 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58

Products for ZSCAN26 Gene

Sources for ZSCAN26 Gene

Content
Loading form....