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Aliases for ZSCAN23 Gene

Aliases for ZSCAN23 Gene

  • Zinc Finger And SCAN Domain Containing 23 2 3 5
  • Zinc Finger Protein 453 2 3 4
  • Zinc Finger Protein 390 2 3 4
  • ZNF390 3 4
  • ZNF453 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 23 3
  • DJ29K1.3.1 3
  • DJ29K1.3 3

External Ids for ZSCAN23 Gene

Previous HGNC Symbols for ZSCAN23 Gene

  • ZNF453
  • ZNF390

Previous GeneCards Identifiers for ZSCAN23 Gene

  • GC06M028513
  • GC06U901203
  • GC06M028399
  • GC06M028206

Summaries for ZSCAN23 Gene

GeneCards Summary for ZSCAN23 Gene

ZSCAN23 (Zinc Finger And SCAN Domain Containing 23) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity. An important paralog of this gene is ZSCAN12.

UniProtKB/Swiss-Prot for ZSCAN23 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZSCAN23 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN23 Gene

Genomics for ZSCAN23 Gene

GeneHancer (GH) Regulatory Elements for ZSCAN23 Gene

Promoters and enhancers for ZSCAN23 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I028442 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 571.4 +0.6 627 1.5 PKNOX1 ATF1 SIN3A ZNF2 ETS1 ZNF121 ZNF143 RUNX3 ZHX2 REST ZSCAN23 ZNF603P ZKSCAN4 ZKSCAN3 ZSCAN9 ZKSCAN8 ZSCAN12 ZSCAN31 PIR55219
GH06I027494 Enhancer 1.3 Ensembl ENCODE 120.7 +948.3 948325 1.7 FEZF1 ZNF213 E2F8 ZNF143 SP3 ZFP41 MEF2D SSRP1 ZNF610 RCOR2 TRS-AGA2-3 ZSCAN12 ZSCAN23 ZKSCAN8 PGBD1 ZNF322 ZKSCAN3 ZSCAN9 ZNF391 ENSG00000261839
GH06I028942 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 55.3 -500.1 -500144 2.3 MLX ZFP64 FEZF1 DMAP1 IRF4 ZNF213 E2F8 ZNF143 SP3 NFYC GC06P028946 LINC01556 TRL-AAG2-2 TRM-CAT3-1 ZSCAN23 ZSCAN12 TRIM27 ZSCAN26 ZKSCAN8 PGBD1
GH06I028802 Enhancer 1.5 Ensembl ENCODE dbSUPER 57 -359.1 -359082 1.1 HDGF PKNOX1 ARNT SIN3A YBX1 ZNF2 ZNF766 ZNF213 ZNF302 E2F8 GC06M028901 GC06M028919 TRA-TGC7-1 ZSCAN12 ZKSCAN3 ZSCAN23 ZKSCAN8 PGBD1 ZKSCAN4 ZSCAN9
GH06I027547 Enhancer 1.3 Ensembl ENCODE 65.5 +895.7 895734 2.1 HDGF ARNT ARID4B FEZF1 ZNF2 POLR2B ZNF213 E2F8 FOS KLF13 GC06M027549 TRQ-CTG2-1 ZSCAN12 ZSCAN23 ZSCAN9 PGBD1 ZKSCAN8 ZNF322 ZSCAN26 ZNF391
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZSCAN23 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZSCAN23 gene promoter:

Genomic Locations for ZSCAN23 Gene

Genomic Locations for ZSCAN23 Gene
18,444 bases
Minus strand

Genomic View for ZSCAN23 Gene

Genes around ZSCAN23 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN23 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN23 Gene

Proteins for ZSCAN23 Gene

  • Protein details for ZSCAN23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger and SCAN domain-containing protein 23
    Protein Accession:
    Secondary Accessions:
    • Q96KV9

    Protein attributes for ZSCAN23 Gene

    389 amino acids
    Molecular mass:
    44955 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAC44641.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for ZSCAN23 Gene

Post-translational modifications for ZSCAN23 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN23 Gene

No data available for DME Specific Peptides for ZSCAN23 Gene

Domains & Families for ZSCAN23 Gene

Gene Families for ZSCAN23 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZSCAN23 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZSCAN23: view

Function for ZSCAN23 Gene

Molecular function for ZSCAN23 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZSCAN23 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN23: view

Phenotypes for ZSCAN23 Gene

GenomeRNAi human phenotypes for ZSCAN23:
genes like me logo Genes that share phenotypes with ZSCAN23: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN23 Gene

Localization for ZSCAN23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN23 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN23 gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZSCAN23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0070062 extracellular exosome IDA,HDA 23376485
genes like me logo Genes that share ontologies with ZSCAN23: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZSCAN23 Gene

Pathways & Interactions for ZSCAN23 Gene

SuperPathways for ZSCAN23 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN23: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN23 Gene

Drugs & Compounds for ZSCAN23 Gene

No Compound Related Data Available

Transcripts for ZSCAN23 Gene

mRNA/cDNA for ZSCAN23 Gene

(6) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZSCAN23 Gene

Zinc finger and SCAN domain containing 23:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN23 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4
SP2: - -

Relevant External Links for ZSCAN23 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZSCAN23 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN23 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN23 Gene:


SOURCE GeneReport for Unigene cluster for ZSCAN23 Gene:

genes like me logo Genes that share expression patterns with ZSCAN23: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN23 Gene

Orthologs for ZSCAN23 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN23 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZSCAN23 33 34
  • 99.74 (n)
(Bos Taurus)
Mammalia ZSCAN23 33 34
  • 86.08 (n)
(Canis familiaris)
Mammalia ZSCAN23 33 34
  • 83.65 (n)
(Monodelphis domestica)
Mammalia ZSCAN23 34
  • 72 (a)
Species where no ortholog for ZSCAN23 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN23 Gene

Gene Tree for ZSCAN23 (if available)
Gene Tree for ZSCAN23 (if available)

Paralogs for ZSCAN23 Gene

(427) SIMAP similar genes for ZSCAN23 Gene using alignment to 2 proteins: Pseudogenes for ZSCAN23 Gene

genes like me logo Genes that share paralogs with ZSCAN23: view

Variants for ZSCAN23 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN23 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000212999 -- 28,442,833(-) G/C 5_prime_UTR_variant, intron_variant
rs1000367057 -- 28,436,188(-) C/T coding_sequence_variant, missense_variant
rs1000398324 -- 28,435,891(-) A/G coding_sequence_variant, synonymous_variant
rs1000473775 -- 28,443,818(-) C/T upstream_transcript_variant
rs1000614825 -- 28,443,490(-) A/C 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant

Variation tolerance for ZSCAN23 Gene

Gene Damage Index Score: 0.96; 19.74% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSCAN23 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZSCAN23 Gene

Disorders for ZSCAN23 Gene

Additional Disease Information for ZSCAN23

No disorders were found for ZSCAN23 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN23 Gene

Publications for ZSCAN23 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M … Moll S (Journal of proteomics 2013) 3 58

Products for ZSCAN23 Gene

Sources for ZSCAN23 Gene

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