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Aliases for ZSCAN20 Gene

Aliases for ZSCAN20 Gene

  • Zinc Finger And SCAN Domain Containing 20 2 3 5
  • Zinc Finger Protein 31 2 3 4
  • Zinc Finger Protein KOX29 3 4
  • Zinc Finger Protein 360 3 4
  • ZNF360 3 4
  • ZNF31 3 4
  • KOX29 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 20 3
  • Zinc Finger Protein 31 (KOX 29) 2
  • ZFP-31 3

External Ids for ZSCAN20 Gene

Previous HGNC Symbols for ZSCAN20 Gene

  • ZNF360
  • ZNF31

Previous GeneCards Identifiers for ZSCAN20 Gene

  • GC01P033710
  • GC01P033938
  • GC01P032054

Summaries for ZSCAN20 Gene

GeneCards Summary for ZSCAN20 Gene

ZSCAN20 (Zinc Finger And SCAN Domain Containing 20) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and chromatin binding. An important paralog of this gene is ZKSCAN2.

UniProtKB/Swiss-Prot for ZSCAN20 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZSCAN20 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN20 Gene

Genomics for ZSCAN20 Gene

GeneHancer (GH) Regulatory Elements for ZSCAN20 Gene

Promoters and enhancers for ZSCAN20 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I033470 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 569.5 -0.9 -890 3.3 HDGF PKNOX1 ZFP64 ARID4B SIN3A ZNF2 YY1 POLR2B ZNF207 ZNF143 ZSCAN20 ZBTB8A RBBP4 ZNF362 PHC2 TLR12P
GH01I033474 Enhancer 0.2 dbSUPER 550.8 +1.9 1854 0.6 ZSCAN20 PHC2 PIR48245
GH01I033035 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 22.3 -436.2 -436211 2.6 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1 AK2 TXLNA KPNA6 RBBP4 TSSK3 ZBTB8A ZSCAN20 EIF3I FAM229A ZBTB8B
GH01I032813 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 19.7 -655.4 -655389 7.3 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 S100PBP YARS TXLNA TSSK3 RBBP4 ZBTB8A KHDRBS1 TMEM39B EIF3I FAM229A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZSCAN20 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZSCAN20 gene promoter:

Genomic Locations for ZSCAN20 Gene

Genomic Locations for ZSCAN20 Gene
28,063 bases
Plus strand

Genomic View for ZSCAN20 Gene

Genes around ZSCAN20 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN20 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN20 Gene

Proteins for ZSCAN20 Gene

  • Protein details for ZSCAN20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger and SCAN domain-containing protein 20
    Protein Accession:
    Secondary Accessions:
    • A8K2D0
    • B1ALI4
    • B1ALI5
    • B1ALI6
    • Q6ZN23
    • Q96FA9
    • Q96H84

    Protein attributes for ZSCAN20 Gene

    1043 amino acids
    Molecular mass:
    117541 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN20 Gene


neXtProt entry for ZSCAN20 Gene

Post-translational modifications for ZSCAN20 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZSCAN20 Gene

Domains & Families for ZSCAN20 Gene

Gene Families for ZSCAN20 Gene

Suggested Antigen Peptide Sequences for ZSCAN20 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZSCAN20: view

Function for ZSCAN20 Gene

Molecular function for ZSCAN20 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZSCAN20 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN20: view
genes like me logo Genes that share phenotypes with ZSCAN20: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN20 Gene

Localization for ZSCAN20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN20 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN20 gene
Compartment Confidence
nucleus 5
mitochondrion 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZSCAN20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSCAN20: view

Pathways & Interactions for ZSCAN20 Gene

SuperPathways for ZSCAN20 Gene

No Data Available

Interacting Proteins for ZSCAN20 Gene

Selected Interacting proteins: P17040-ZSC20_HUMAN for ZSCAN20 Gene via IID

Gene Ontology (GO) - Biological Process for ZSCAN20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN20: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN20 Gene

Drugs & Compounds for ZSCAN20 Gene

No Compound Related Data Available

Transcripts for ZSCAN20 Gene

Unigene Clusters for ZSCAN20 Gene

Zinc finger and SCAN domain containing 20:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN20 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8
SP1: -
SP2: - - -

Relevant External Links for ZSCAN20 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZSCAN20 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN20 Gene

Protein differential expression in normal tissues from HIPED for ZSCAN20 Gene

This gene is overexpressed in Plasma (27.6), Monocytes (23.4), and Tlymphocyte (18.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZSCAN20 Gene

Protein tissue co-expression partners for ZSCAN20 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN20 Gene:


SOURCE GeneReport for Unigene cluster for ZSCAN20 Gene:


Evidence on tissue expression from TISSUES for ZSCAN20 Gene

  • Nervous system(4.2)
  • Eye(4.1)
  • Muscle(4.1)
genes like me logo Genes that share expression patterns with ZSCAN20: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN20 Gene

Orthologs for ZSCAN20 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSCAN20 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZSCAN20 33 34
  • 99.62 (n)
(Canis familiaris)
Mammalia ZSCAN20 33 34
  • 87.17 (n)
(Bos Taurus)
Mammalia ZSCAN20 33 34
  • 85.37 (n)
(Mus musculus)
Mammalia Zscan20 33 16 34
  • 80.46 (n)
(Rattus norvegicus)
Mammalia Zscan20 33
  • 80.2 (n)
(Monodelphis domestica)
Mammalia ZSCAN20 34
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia ZSCAN20 34
  • 64 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 42 (a)
-- 34
  • 32 (a)
Species where no ortholog for ZSCAN20 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN20 Gene

Gene Tree for ZSCAN20 (if available)
Gene Tree for ZSCAN20 (if available)

Paralogs for ZSCAN20 Gene

Paralogs for ZSCAN20 Gene

(390) SIMAP similar genes for ZSCAN20 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZSCAN20: view

Variants for ZSCAN20 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN20 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000121903 -- 33,504,361(+) G/A downstream_transcript_variant
rs1000159162 -- 33,498,403(+) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000169805 -- 33,471,750(+) T/A/G upstream_transcript_variant
rs1000208654 -- 33,490,845(+) T/A intron_variant
rs1000417249 -- 33,474,835(+) T/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN20 Gene

Variant ID Type Subtype PubMed ID
esv3585686 CNV gain 21293372
esv3585687 CNV gain 21293372
nsv834613 CNV gain 17160897
nsv344 CNV insertion 18451855
nsv1137748 CNV deletion 24896259
esv3585689 CNV gain 21293372

Variation tolerance for ZSCAN20 Gene

Residual Variation Intolerance Score: 14.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.80; 47.53% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSCAN20 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN20 Gene

Disorders for ZSCAN20 Gene

Additional Disease Information for ZSCAN20

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ZSCAN20 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN20 Gene

Publications for ZSCAN20 Gene

  1. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen HJ (The New biologist 1990) 2 3 4 58
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for ZSCAN20 Gene

Sources for ZSCAN20 Gene

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