Aliases for ZNRF3 Gene
Aliases for ZNRF3 Gene
External Ids for ZNRF3 Gene
- HGNC: 18126
- Entrez Gene: 84133
- Ensembl: ENSG00000183579
- OMIM: 612062
- UniProtKB: Q9ULT6
Previous GeneCards Identifiers for ZNRF3 Gene
- GC22P027605
- GC22P029279
- GC22P012347
- GC22P028883
Summaries for ZNRF3 Gene
GeneCards Summary for ZNRF3 Gene
ZNRF3 (Zinc And Ring Finger 3) is a Protein Coding gene. Diseases associated with ZNRF3 include Osteoblastoma and Pseudosarcomatous Fibromatosis. Among its related pathways are Signaling by GPCR and Wnt Signaling Pathways: beta-Catenin-dependent Wnt Signaling. Gene Ontology (GO) annotations related to this gene include ligase activity and frizzled binding. An important paralog of this gene is RNF43.
UniProtKB/Swiss-Prot for ZNRF3 Gene
-
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Additional gene information for ZNRF3 Gene
- Monarch Initiative
- Search for ZNRF3 at DataMed
- Search for ZNRF3 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNRF3 Gene
Genomics for ZNRF3 Gene
GeneHancer (GH) Regulatory Elements for ZNRF3 Gene
Promoters and enhancers for ZNRF3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ZNRF3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ZNRF3 Gene
Genomic Locations for ZNRF3 Gene
- chr22:28,800,654-29,057,488
- (GRCh38/hg38)
- Size:
- 256,835 bases
- Orientation:
- Plus strand
- chr22:29,279,580-29,453,476
- (GRCh37/hg19)
Genomic View for ZNRF3 Gene
Genes around ZNRF3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q12.1 by Ensembl
- 22q12.1 by Entrez Gene
- 22q12.1 by HGNC
ZNRF3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNRF3 Gene
Proteins for ZNRF3 Gene
-
Protein details for ZNRF3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9ULT6-ZNRF3_HUMAN
- Recommended name:
- E3 ubiquitin-protein ligase ZNRF3
- Protein Accession:
- Q9ULT6
- B3KU18
- Q6ICH1
- Q6NTF8
- Q8WU18
Protein attributes for ZNRF3 Gene
- Size:
- 936 amino acids
- Molecular mass:
- 100574 Da
- Quaternary structure:
-
- Interacts with LRP6, FZD4, FZD5, FZD6 and FZD8. Interacts with RSPO1; interaction promotes indirect interaction with LGR4 and membrane clearance of ZNRF3.
- SequenceCaution:
-
- Sequence=CAG30283.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for ZNRF3 Gene
Post-translational modifications for ZNRF3 Gene
Other Protein References for ZNRF3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for ZNRF3 (ZNRF3)
- Novus Biologicals Antibodies for ZNRF3
- Invitrogen Antibodies for ZNRF3
- Search GeneTex for Antibodies for ZNRF3
Protein Products
- R&D Systems Proteins and Enzymes for ZNRF3
-
OriGene Purified Proteins for ZNRF3
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNRF3
- Origene Custom Protein Services for ZNRF3
- Novus Biologicals proteins for ZNRF3
- Search GeneTex for Proteins for ZNRF3
Assay Products
No data available for DME Specific Peptides for ZNRF3 Gene
Domains & Families for ZNRF3 Gene
Gene Families for ZNRF3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted membrane proteins
Protein Domains for ZNRF3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNRF3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9ULT6- Family:
-
- Belongs to the ZNRF3 family.
Function for ZNRF3 Gene
Molecular function for ZNRF3 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Negatively regulated by R-spondin proteins such as RSPO1: interaction with RSPO1 induces the indirect association between ZNRF3 and LGR4, promoting membrane clearance of ZNRF3.
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Enzyme Numbers (IUBMB) for ZNRF3 Gene
Phenotypes From GWAS Catalog for ZNRF3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IDA | 22575959 |
| GO:0005109 | frizzled binding | IPI | 22575959 |
| GO:0005515 | protein binding | IPI | 22575959 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZNRF3 Gene
- MGI mutant phenotypes for ZNRF3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ZNRF3:
Animal Models for ZNRF3 Gene
- MGI Knock Outs for ZNRF3:
-
- Znrf3 tm1.1Fcon
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNRF3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNRF3 gene
- Search ViGene Biosciences for ZNRF3
CRISPR Products
-
OriGene CRISPR knockouts for ZNRF3
- genomics-online: gRNA clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNRF3
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miRNA for ZNRF3 Gene
- miRTarBase miRNAs that target ZNRF3
-
- hsa-mir-103a-3p (MIRT027017)
- hsa-mir-16-5p (MIRT031450)
- hsa-mir-339-5p (MIRT042789)
- hsa-mir-15a-5p (MIRT087424)
- hsa-mir-15b-5p (MIRT087425)
- hsa-mir-195-5p (MIRT087426)
- hsa-mir-424-5p (MIRT087428)
- hsa-mir-497-5p (MIRT087429)
- hsa-mir-4524a-5p (MIRT087431)
- hsa-mir-4524b-5p (MIRT087433)
- hsa-mir-6838-5p (MIRT087435)
- hsa-mir-940 (MIRT370506)
- hsa-mir-1910-3p (MIRT370507)
- hsa-mir-6511a-5p (MIRT370516)
- hsa-mir-6808-5p (MIRT370517)
- hsa-mir-6893-5p (MIRT370519)
- hsa-mir-146b-5p (MIRT438327)
- hsa-mir-215-5p (MIRT444118)
- hsa-mir-192-5p (MIRT444119)
- hsa-mir-376b-3p (MIRT444120)
- hsa-mir-376a-3p (MIRT444121)
- hsa-mir-631 (MIRT444122)
- hsa-mir-3661 (MIRT444123)
- hsa-mir-103b (MIRT444124)
- hsa-mir-646 (MIRT444125)
- hsa-mir-503-5p (MIRT444126)
- hsa-mir-6516-5p (MIRT462897)
- hsa-mir-4535 (MIRT462898)
- hsa-mir-4776-5p (MIRT462899)
- hsa-mir-455-3p (MIRT462900)
- hsa-mir-4325 (MIRT462901)
- hsa-mir-7703 (MIRT462902)
- hsa-mir-1294 (MIRT462903)
- hsa-mir-650 (MIRT462904)
- hsa-mir-3612 (MIRT462905)
- hsa-mir-711 (MIRT462906)
- hsa-mir-6499-3p (MIRT462907)
- hsa-mir-4722-5p (MIRT462908)
- hsa-mir-2467-3p (MIRT462909)
- hsa-mir-6086 (MIRT462910)
- hsa-mir-377-5p (MIRT462911)
- hsa-mir-6134 (MIRT462912)
- hsa-mir-7854-3p (MIRT462913)
- hsa-mir-1827 (MIRT462914)
- hsa-mir-4649-3p (MIRT462915)
- hsa-mir-1292-3p (MIRT462916)
- hsa-mir-1247-3p (MIRT462917)
- hsa-mir-4768-3p (MIRT462918)
- hsa-mir-4257 (MIRT462919)
- hsa-mir-6500-3p (MIRT462920)
- hsa-mir-3614-5p (MIRT462921)
- hsa-mir-92b-3p (MIRT462922)
- hsa-mir-92a-3p (MIRT462923)
- hsa-mir-367-3p (MIRT462924)
- hsa-mir-363-3p (MIRT462925)
- hsa-mir-32-5p (MIRT462926)
- hsa-mir-25-3p (MIRT462927)
- hsa-mir-890 (MIRT462928)
- hsa-mir-34b-3p (MIRT462929)
- hsa-mir-93-5p (MIRT734875)
miRNA Products
- Search ViGene Biosciences for ZNRF3
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNRF3
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- genomics-online: shRNA clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for ZNRF3 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNRF3
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ZNRF3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for ZNRF3
Cell Line Products
-
Horizon Cell Lines for ZNRF3
-
ViGene Biosciences adenoviral particle packaged cDNA for ZNRF3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNRF3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNRF3 gene
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ZNRF3 Gene
Localization for ZNRF3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNRF3 Gene
- Cell membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
- Golgi apparatus (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | IDA | 22575959 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for ZNRF3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by Wnt |
.71
|
|
| 2 | Wnt Signaling Pathways: beta-Catenin-dependent Wnt Signaling | ||
| 3 | Regulation of FZD by ubiquitination | ||
| 4 | Signaling by GPCR | ||
Pathways by source for ZNRF3 Gene
4 Reactome pathways for ZNRF3 Gene
1 R&D Systems pathway for ZNRF3 Gene
UniProtKB/Swiss-Prot Q9ULT6-ZNRF3_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for ZNRF3 Gene
Selected Interacting proteins:
Q9ULT6-ZNRF3_HUMAN
ENSP00000443824
for ZNRF3 Gene via
IID
STRING
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process | IMP | 22575959 |
| GO:0016055 | Wnt signaling pathway | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0030178 | negative regulation of Wnt signaling pathway | IEA | -- |
| GO:0038018 | Wnt receptor catabolic process | TAS | 24431302 |
Transcripts for ZNRF3 Gene
mRNA/cDNA for ZNRF3 Gene
- (7) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (1) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZNRF3 Gene
- Zinc and ring finger 3:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ZNRF3
- genomics-online: gRNA clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
- Applied Biological Materials CRISPR for ZNRF3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNRF3
- GenScript: Design CRISPR guide RNA sequences for ZNRF3
miRNA Products
- Search ViGene Biosciences for ZNRF3
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNRF3
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- genomics-online: shRNA clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNRF3 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNRF3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNRF3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ZNRF3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for ZNRF3
Expression for ZNRF3 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNRF3 Gene
NURSA nuclear receptor signaling pathways regulating expression of ZNRF3 Gene:
ZNRF3SOURCE GeneReport for Unigene cluster for ZNRF3 Gene:
Hs.655242Evidence on tissue expression from TISSUES for ZNRF3 Gene
- Nervous system(4.3)
- Muscle(4.1)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for ZNRF3
-
OriGene qPCR primer pairs for ZNRF3
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- Overview of 65 available ZNRF3 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNRF3 Gene
Orthologs for ZNRF3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZNRF3 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | ZNRF3 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Znrf3 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Znrf3 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZNRF3 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ZNRF3 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ZNRF3 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZNRF3 33 34 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | znrf3 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | znrf3 33 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | Y47D3B.11 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8714 34 |
|
OneToMany |
- Species where no ortholog for ZNRF3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ZNRF3 Gene
Variants for ZNRF3 Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004119 | -- | 29,015,959(+) | T/C | intron_variant | |
| rs1000005096 | -- | 28,900,704(+) | G/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000010206 | -- | 28,951,501(+) | G/A | intron_variant | |
| rs1000015607 | -- | 28,994,863(+) | G/A | intron_variant | |
| rs1000038285 | -- | 28,816,657(+) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2657238 | CNV | deletion | 23128226 |
| esv26777 | CNV | loss | 19812545 |
| esv3647523 | CNV | loss | 21293372 |
| nsv1064079 | CNV | gain | 25217958 |
| nsv1072633 | CNV | deletion | 25765185 |
| nsv3589 | CNV | deletion | 18451855 |
| nsv471980 | CNV | novel sequence insertion | 20440878 |
| nsv476091 | CNV | novel sequence insertion | 20440878 |
| nsv834169 | CNV | loss | 17160897 |
| nsv953066 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
10.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.10;
38.27% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNRF3 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNRF3 Gene
Disorders for ZNRF3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| osteoblastoma |
|
|
| pseudosarcomatous fibromatosis |
|
|
Search ZNRF3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNRF3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNRF3 Gene
Publications for ZNRF3 Gene
- Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 2 3 4 58
- ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. (PMID: 22575959) Hao HX … Cong F (Nature 2012) 3 4 58
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. (PMID: 20935629) Heid IM … Lindgren CM (Nature genetics 2010) 3 44 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 19 available ZNRF3 Antibodies ranked by validation data
- Compare Top ZNRF3 Antibodies
- antibodies-online: Search results for available ZNRF3 related products ranked by validation data
- antibodies-online: Search results for 3 available ZNRF3 Proteins ranked by validation data
- Compare Top ZNRF3 Proteins
- Search GeneTex for Antibodies for ZNRF3
- Search GeneTex for Proteins for ZNRF3
- ViGene Biosciences adenoviral particle packaged cDNA for ZNRF3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ZNRF3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZNRF3 gene
- Search ViGene Biosciences for ZNRF3
- Horizon Cell Lines for ZNRF3
- genomics-online: cdna clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
- orf clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
- genomics-online: gRNA clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
- genomics-online: primer clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
- genomics-online: shRNA clones - Search results for 65 available ZNRF3 gene related products
- Overview of 65 available ZNRF3 gene related products
Sources for ZNRF3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems