Aliases for ZNF888 Gene

Aliases for ZNF888 Gene

  • Zinc Finger Protein 888 2 3 4 5
  • CTD-2331H12.6 3

External Ids for ZNF888 Gene

Previous GeneCards Identifiers for ZNF888 Gene

  • GC19M053410

Summaries for ZNF888 Gene

GeneCards Summary for ZNF888 Gene

ZNF888 (Zinc Finger Protein 888) is a Protein Coding gene. An important paralog of this gene is ZNF813.

UniProtKB/Swiss-Prot Summary for ZNF888 Gene

Additional gene information for ZNF888 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF888 Gene

Genomics for ZNF888 Gene

GeneHancer (GH) Regulatory Elements for ZNF888 Gene

Promoters and enhancers for ZNF888 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF888 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF888

Genomic Locations for ZNF888 Gene

Genomic Locations for ZNF888 Gene
chr19:52,904,417-52,923,481
(GRCh38/hg38)
Size:
19,065 bases
Orientation:
Minus strand
chr19:53,408,210-53,426,723
(GRCh37/hg19)
Size:
18,514 bases
Orientation:
Minus strand

Genomic View for ZNF888 Gene

Genes around ZNF888 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF888 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF888 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF888 Gene

Proteins for ZNF888 Gene

  • Protein details for ZNF888 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CJ79-ZN888_HUMAN
    Recommended name:
    Zinc finger protein 888
    Protein Accession:
    P0CJ79
    Secondary Accessions:
    • A0A1W2PQ69

    Protein attributes for ZNF888 Gene

    Size:
    718 amino acids
    Molecular mass:
    83549 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF888 Gene

Post-translational modifications for ZNF888 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF888 Gene

No data available for DME Specific Peptides for ZNF888 Gene

Domains & Families for ZNF888 Gene

Gene Families for ZNF888 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF888 Gene

Suggested Antigen Peptide Sequences for ZNF888 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 888 (ZN888_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P0CJ79

UniProtKB/Swiss-Prot:

ZN888_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF888: view

Function for ZNF888 Gene

Molecular function for ZNF888 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF888 Gene

Gene Ontology (GO) - Molecular Function for ZNF888 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF888: view

Phenotypes for ZNF888 Gene

genes like me logo Genes that share phenotypes with ZNF888: view

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF888 Gene

Localization for ZNF888 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF888 Gene

Gene Ontology (GO) - Cellular Components for ZNF888 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF888: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ZNF888 Gene

Pathways & Interactions for ZNF888 Gene

PathCards logo

SuperPathways for ZNF888 Gene

No Data Available

Interacting Proteins for ZNF888 Gene

Selected Interacting proteins: P0CJ79-ZN888_HUMAN for ZNF888 Gene via IID

Symbol External ID(s) Details
ZNF324B
ZNF354C
;

Gene Ontology (GO) - Biological Process for ZNF888 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF888: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF888 Gene

Drugs & Compounds for ZNF888 Gene

No Compound Related Data Available

Transcripts for ZNF888 Gene

mRNA/cDNA for ZNF888 Gene

1 REFSEQ mRNAs :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF888 Gene

No ASD Table

Relevant External Links for ZNF888 Gene

GeneLoc Exon Structure for
ZNF888

Expression for ZNF888 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF888 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF888 Gene

This gene is overexpressed in Bladder (x7.3).

Protein differential expression in normal tissues from HIPED for ZNF888 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (52.8) and Amniocyte (16.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF888 Gene



Protein tissue co-expression partners for ZNF888 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF888

genes like me logo Genes that share expression patterns with ZNF888: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF888 Gene

Orthologs for ZNF888 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF888 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC456268 30
  • 95.44 (n)
Species where no ortholog for ZNF888 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF888 Gene

ENSEMBL:
Gene Tree for ZNF888 (if available)
TreeFam:
Gene Tree for ZNF888 (if available)

Paralogs for ZNF888 Gene

(539) SIMAP similar genes for ZNF888 Gene using alignment to 1 proteins:

  • ZN888_HUMAN
genes like me logo Genes that share paralogs with ZNF888: view

Variants for ZNF888 Gene

Additional dbSNP identifiers (rs#s) for ZNF888 Gene

Additional Variant Information for ZNF888 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF888

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for ZNF888 Gene

Disorders for ZNF888 Gene

Additional Disease Information for ZNF888

No disorders were found for ZNF888 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF888 Gene

Publications for ZNF888 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 54
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54

Products for ZNF888 Gene

Sources for ZNF888 Gene