Aliases for ZNF853 Gene

Aliases for ZNF853 Gene

  • Zinc Finger Protein 853 2 3 4 5
  • DKFZp434J1015 2
  • ZNF853 5

External Ids for ZNF853 Gene

Previous GeneCards Identifiers for ZNF853 Gene

  • GC07P006649
  • GC07P006621
  • GC07P006656
  • GC07P006657
  • GC07P006661

Summaries for ZNF853 Gene

GeneCards Summary for ZNF853 Gene

ZNF853 (Zinc Finger Protein 853) is a Protein Coding gene. Diseases associated with ZNF853 include Cribriform Carcinoma. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF500.

Additional gene information for ZNF853 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF853 Gene

Genomics for ZNF853 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF853 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF853 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF853

Top Transcription factor binding sites by QIAGEN in the ZNF853 gene promoter:
  • AML1a
  • c-Ets-1
  • E47
  • Lmo2
  • NF-1
  • Pax-5
  • Tal-1
  • Zic3

Genomic Locations for ZNF853 Gene

Genomic Locations for ZNF853 Gene
8,681 bases
Plus strand
8,674 bases
Plus strand

Genomic View for ZNF853 Gene

Genes around ZNF853 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF853 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF853 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF853 Gene

Proteins for ZNF853 Gene

  • Protein details for ZNF853 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 853
    Protein Accession:

    Protein attributes for ZNF853 Gene

    659 amino acids
    Molecular mass:
    74878 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF853 Gene

Post-translational modifications for ZNF853 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF853 Gene

No data available for DME Specific Peptides for ZNF853 Gene

Domains & Families for ZNF853 Gene

Gene Families for ZNF853 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF853 Gene


Suggested Antigen Peptide Sequences for ZNF853 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 853 (ZN853_HUMAN)
genes like me logo Genes that share domains with ZNF853: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ZNF853 Gene

Function for ZNF853 Gene

Phenotypes From GWAS Catalog for ZNF853 Gene

Gene Ontology (GO) - Molecular Function for ZNF853 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF853: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF853

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF853 Gene

Localization for ZNF853 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZNF853 Gene

Pathways & Interactions for ZNF853 Gene

PathCards logo

SuperPathways for ZNF853 Gene

genes like me logo Genes that share pathways with ZNF853: view

Pathways by source for ZNF853 Gene

1 KEGG pathway for ZNF853 Gene

Interacting Proteins for ZNF853 Gene

Gene Ontology (GO) - Biological Process for ZNF853 Gene


No data available for SIGNOR curated interactions for ZNF853 Gene

Drugs & Compounds for ZNF853 Gene

No Compound Related Data Available

Transcripts for ZNF853 Gene

mRNA/cDNA for ZNF853 Gene

3 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF853

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF853 Gene

No ASD Table

Relevant External Links for ZNF853 Gene

GeneLoc Exon Structure for

Expression for ZNF853 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF853 Gene

Protein differential expression in normal tissues from HIPED for ZNF853 Gene

This gene is overexpressed in Heart (59.7) and CD8 Tcells (9.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF853 Gene

Protein tissue co-expression partners for ZNF853 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF853

SOURCE GeneReport for Unigene cluster for ZNF853 Gene:

genes like me logo Genes that share expression patterns with ZNF853: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF853 Gene

Orthologs for ZNF853 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF853 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF853 31
  • 45 (a)
(Mus musculus)
Mammalia Zfp853 31
  • 39 (a)
(Monodelphis domestica)
Mammalia -- 31
  • 13 (a)
(Danio rerio)
Actinopterygii ZNF787 31
  • 31 (a)
Fruit Fly
(Drosophila melanogaster)
Insecta phol 31
  • 7 (a)
pho 31
  • 7 (a)
Species where no ortholog for ZNF853 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ZNF853 Gene

Gene Tree for ZNF853 (if available)
Gene Tree for ZNF853 (if available)
Evolutionary constrained regions (ECRs) for ZNF853: view image

Paralogs for ZNF853 Gene

genes like me logo Genes that share paralogs with ZNF853: view

Variants for ZNF853 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF853 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
rs11971880 - p.Gln212Glu
rs1806552 - p.Gln30Arg
rs2243563 - p.Gly8Arg

Additional dbSNP identifiers (rs#s) for ZNF853 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF853 Gene

Variant ID Type Subtype PubMed ID
dgv1090n67 CNV gain 20364138
dgv11172n54 CNV loss 21841781
dgv11173n54 CNV loss 21841781
esv1914954 OTHER inversion 16254605
nsv1020236 CNV gain 25217958
nsv436904 CNV insertion 17901297
nsv508444 CNV deletion 20534489
nsv515978 CNV loss 19592680
nsv606003 CNV loss 21841781
nsv606006 CNV loss 21841781
nsv7392 OTHER inversion 18451855
nsv830895 CNV loss 17160897
nsv950804 CNV deletion 24416366

Variation tolerance for ZNF853 Gene

Gene Damage Index Score: 5.62; 72.59% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF853 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF853 Gene

Disorders for ZNF853 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF853 Gene - From: DISEASES

Disorder Aliases PubMed IDs
cribriform carcinoma
  • ductal carcinoma, cribriform type
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with ZNF853: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF853 Gene

Publications for ZNF853 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 3 4
  2. KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks. (PMID: 28273063) Imbeault M … Trono D (Nature 2017) 3
  3. Cys2His2 zinc finger protein family: classification, functions, and major members. (PMID: 22803940) Razin SV … Kantidze OL (Biochemistry. Biokhimiia 2012) 3
  4. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N … Gygi SP (Proceedings of the National Academy of Sciences of the United States of America 2008) 3

Products for ZNF853 Gene

Sources for ZNF853 Gene