Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF852 Gene

Aliases for ZNF852 Gene

  • Zinc Finger Protein 852 2 3 5

External Ids for ZNF852 Gene

Previous GeneCards Identifiers for ZNF852 Gene

  • GC03P044513
  • GC03M044517

Summaries for ZNF852 Gene

GeneCards Summary for ZNF852 Gene

ZNF852 (Zinc Finger Protein 852) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZKSCAN7.

UniProtKB/Swiss-Prot for ZNF852 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF852 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF852 Gene

Genomics for ZNF852 Gene

GeneHancer (GH) Regulatory Elements for ZNF852 Gene

Promoters and enhancers for ZNF852 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I044509 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 563.8 -0.1 -59 2.6 HDGF ATF1 ARNT ARID4B SIN3A ZNF2 ZNF48 YY1 TCF12 POLR2B ZNF852 ZNF660 ZNF197 ZNF35 ZDHHC3 ZNF502 EI24P3
GH03I045117 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 31.6 -612.3 -612349 10.7 HDGF PKNOX1 ARNT SIN3A ATF7 FOS ZNF623 ZNF592 ATF4 GMEB1 RN7SL145P ZNF852 LIMD1 ZNF502 ZNF445 TMEM158 ZNF197 FYCO1 CDCP1 RNU5B-3P
GH03I044760 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 23.7 -251.4 -251413 2.5 PKNOX1 SMAD1 MLX ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B KIAA1143 KIF15 ZNF852 RN7SL145P HNRNPA1P77
GH03I044624 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 21.6 -114.7 -114657 2.2 PKNOX1 ARNT ARID4B SIN3A YY1 POLR2B ZNF766 CBX5 E2F8 ZNF143 ZNF197 ZNF197-AS1 ZNF35 ZNF852 KIAA1143 ZNF660 ZDHHC3 ZNF502 ZNF445 ENSG00000236869
GH03I045130 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 25.3 -625.4 -625351 11.1 HDGF PKNOX1 SMAD1 ARNT POLR2B ZNF766 CBX5 E2F8 FOS REST ZNF502 ZNF852 RN7SL145P ZNF35 ZNF197 RNU5B-3P CLEC3B TMEM158 SACM1L ZDHHC3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF852 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF852 gene promoter:

Genomic Locations for ZNF852 Gene

Genomic Locations for ZNF852 Gene
11,671 bases
Minus strand

Genomic View for ZNF852 Gene

Genes around ZNF852 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF852 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF852 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF852 Gene

Proteins for ZNF852 Gene

  • Protein details for ZNF852 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 852
    Protein Accession:
    Secondary Accessions:
    • B4DLD7

    Protein attributes for ZNF852 Gene

    543 amino acids
    Molecular mass:
    62084 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAG59499.1; Type=Frameshift; Positions=494, 534; Evidence={ECO:0000305};

neXtProt entry for ZNF852 Gene

Post-translational modifications for ZNF852 Gene

No Post-translational modifications

Other Protein References for ZNF852 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF852 Gene

Domains & Families for ZNF852 Gene

Gene Families for ZNF852 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF852 Gene

Suggested Antigen Peptide Sequences for ZNF852 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF852: view

Function for ZNF852 Gene

Molecular function for ZNF852 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF852 Gene

Gene Ontology (GO) - Molecular Function for ZNF852 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF852: view

Phenotypes for ZNF852 Gene

GenomeRNAi human phenotypes for ZNF852:
genes like me logo Genes that share phenotypes with ZNF852: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF852 Gene

Localization for ZNF852 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF852 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF852 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF852 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF852: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF852 Gene

Pathways & Interactions for ZNF852 Gene

SuperPathways for ZNF852 Gene

No Data Available

Interacting Proteins for ZNF852 Gene

Gene Ontology (GO) - Biological Process for ZNF852 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF852: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF852 Gene

Drugs & Compounds for ZNF852 Gene

No Compound Related Data Available

Transcripts for ZNF852 Gene

mRNA/cDNA for ZNF852 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF852 Gene

Zinc finger protein 852:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF852 Gene

No ASD Table

Relevant External Links for ZNF852 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF852 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF852 Gene

Protein differential expression in normal tissues from HIPED for ZNF852 Gene

This gene is overexpressed in Spinal cord (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF852 Gene

Protein tissue co-expression partners for ZNF852 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF852 Gene:


SOURCE GeneReport for Unigene cluster for ZNF852 Gene:

genes like me logo Genes that share expression patterns with ZNF852: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF852 Gene

Orthologs for ZNF852 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF852 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF852 33 34
  • 85.8 (n)
(Bos Taurus)
Mammalia ZKSCAN7 33
  • 84.61 (n)
-- 34
  • 52 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 54 (a)
-- 34
  • 51 (a)
-- 34
  • 48 (a)
-- 34
  • 36 (a)
(Mus musculus)
Mammalia Zkscan7 34
  • 47 (a)
(Gallus gallus)
Aves -- 34
  • 44 (a)
Species where no ortholog for ZNF852 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF852 Gene

Gene Tree for ZNF852 (if available)
Gene Tree for ZNF852 (if available)

Paralogs for ZNF852 Gene

(528) SIMAP similar genes for ZNF852 Gene using alignment to 1 proteins: Pseudogenes for ZNF852 Gene

genes like me logo Genes that share paralogs with ZNF852: view

Variants for ZNF852 Gene

Sequence variations from dbSNP and Humsavar for ZNF852 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000038171 -- 44,508,155(-) T/G intron_variant
rs1000269225 -- 44,501,876(-) G/A intron_variant
rs1000414583 -- 44,512,365(-) A/G upstream_transcript_variant
rs1000866969 -- 44,507,286(-) T/C intron_variant
rs1000973999 -- 44,500,726(-) A/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF852 Gene

Variant ID Type Subtype PubMed ID
nsv965161 CNV duplication 23825009
esv2725213 CNV deletion 23290073

Variation tolerance for ZNF852 Gene

Gene Damage Index Score: 1.32; 26.19% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF852 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF852 Gene

Disorders for ZNF852 Gene

Additional Disease Information for ZNF852

No disorders were found for ZNF852 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF852 Gene

Publications for ZNF852 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  2. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4 58
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 58
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF852 Gene

Sources for ZNF852 Gene

Loading form....