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Aliases for ZNF845 Gene

Aliases for ZNF845 Gene

  • Zinc Finger Protein 845 2 3 5

External Ids for ZNF845 Gene

Previous GeneCards Identifiers for ZNF845 Gene

  • GC19P058546
  • GC19P053837
  • GC19P050157

Summaries for ZNF845 Gene

GeneCards Summary for ZNF845 Gene

ZNF845 (Zinc Finger Protein 845) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF160.

UniProtKB/Swiss-Prot for ZNF845 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF845 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF845 Gene

Genomics for ZNF845 Gene

GeneHancer (GH) Regulatory Elements for ZNF845 Gene

Promoters and enhancers for ZNF845 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I053332 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 559.7 0.0 -13 2.2 HDGF PKNOX1 ARID4B SIN3A ZNF48 POLR2B ZNF416 ZNF143 RUNX3 SP3 ZNF845 PRPF31 ZNF677 ENSG00000268970 VN1R6P
GH19I054199 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 52.5 +872.0 871996 12.1 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 RPS9 PRPF31 LENG8 LENG8-AS1 CNOT3 ZNF525 ZNF845 ENSG00000235681 LILRB5 ZNF765
GH19I053977 Promoter/Enhancer 1.7 Ensembl ENCODE 40.7 +646.2 646248 5.8 HDGF PKNOX1 CLOCK SIN3A FEZF1 ZNF2 ZNF766 ZNF213 ZNF143 SP3 PRPF31 ZNF525 LENG8-AS1 ZNF160 ZNF845 ZNF665 ZNF761 ZNF347 LENG8 ENSG00000235681
GH19I053466 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 30.6 +134.2 134177 1.8 PKNOX1 ATF1 ARID4B DMAP1 SLC30A9 POLR2B E2F8 ATF7 SP3 SP5 ZNF813 CNOT3 ZNF701 ZNF600 LENG8 ZNF845 ZNF808 ENSG00000269001 ENSG00000268970 ZNF160
GH19I053864 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 21.9 +535.2 535200 9.8 HDGF FOXA2 MLX ZFP64 ARID4B NEUROD1 SIN3A DMAP1 ZBTB7B SLC30A9 MYADM LOC105372457 ENSG00000269001 ZNF845 ZNF765 ZNF816 LENG8 ENSG00000235681 ZNF813 TPM3P6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF845 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF845 gene promoter:

Genomic Locations for ZNF845 Gene

Genomic Locations for ZNF845 Gene
21,156 bases
Plus strand

Genomic View for ZNF845 Gene

Genes around ZNF845 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF845 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF845 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF845 Gene

Proteins for ZNF845 Gene

  • Protein details for ZNF845 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 845
    Protein Accession:

    Protein attributes for ZNF845 Gene

    970 amino acids
    Molecular mass:
    113133 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF845 Gene

Post-translational modifications for ZNF845 Gene

No Post-translational modifications

Other Protein References for ZNF845 Gene

No data available for DME Specific Peptides for ZNF845 Gene

Domains & Families for ZNF845 Gene

Gene Families for ZNF845 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF845 Gene

Suggested Antigen Peptide Sequences for ZNF845 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF845: view

Function for ZNF845 Gene

Molecular function for ZNF845 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF845 Gene

Gene Ontology (GO) - Molecular Function for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF845: view
genes like me logo Genes that share phenotypes with ZNF845: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF845 Gene

Localization for ZNF845 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF845 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF845 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF845: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF845 Gene

Pathways & Interactions for ZNF845 Gene

SuperPathways for ZNF845 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF845: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF845 Gene

Drugs & Compounds for ZNF845 Gene

No Compound Related Data Available

Transcripts for ZNF845 Gene

mRNA/cDNA for ZNF845 Gene

(4) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF845 Gene

Zinc finger protein 845:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF845 Gene

No ASD Table

Relevant External Links for ZNF845 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF845 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF845 Gene

Protein differential expression in normal tissues from HIPED for ZNF845 Gene

This gene is overexpressed in Placenta (58.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF845 Gene

Protein tissue co-expression partners for ZNF845 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF845 Gene:


SOURCE GeneReport for Unigene cluster for ZNF845 Gene:


Evidence on tissue expression from TISSUES for ZNF845 Gene

  • Nervous system(4.2)
  • Eye(4.1)
genes like me logo Genes that share expression patterns with ZNF845: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF845 Gene

Orthologs for ZNF845 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF845 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF845 33 34
  • 99.07 (n)
(Rattus norvegicus)
Mammalia LOC102548633 33
  • 61.99 (n)
(Mus musculus)
Mammalia LOC101055890 33
  • 61.39 (n)
Gm4944 34
  • 50 (a)
Gm31526 16
(Bos Taurus)
Mammalia -- 34
  • 44 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 48 (a)
-- 34
  • 46 (a)
-- 34
  • 41 (a)
-- 34
  • 41 (a)
-- 34
  • 36 (a)
CSA.1668 34
  • 36 (a)
Species where no ortholog for ZNF845 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF845 Gene

Gene Tree for ZNF845 (if available)
Gene Tree for ZNF845 (if available)

Paralogs for ZNF845 Gene

(531) SIMAP similar genes for ZNF845 Gene using alignment to 2 proteins: Pseudogenes for ZNF845 Gene

genes like me logo Genes that share paralogs with ZNF845: view

Variants for ZNF845 Gene

Sequence variations from dbSNP and Humsavar for ZNF845 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000033558 -- 53,353,557(+) A/C/G coding_sequence_variant, missense_variant
rs1000140526 -- 53,351,132(+) A/T coding_sequence_variant, missense_variant
rs1000231534 -- 53,346,666(+) G/A intron_variant
rs1000374760 -- 53,343,039(+) G/A intron_variant
rs1000389940 -- 53,342,280(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF845 Gene

Variant ID Type Subtype PubMed ID
nsv978846 CNV duplication 23825009
nsv580080 CNV loss 21841781
nsv1141887 OTHER inversion 24896259
nsv1078889 OTHER inversion 25765185
nsv1055773 CNV gain 25217958
esv3644750 CNV gain 21293372
esv2718816 CNV deletion 23290073
esv2718812 CNV deletion 23290073
esv2718787 CNV deletion 23290073
esv2670793 CNV deletion 23128226
dgv670e214 CNV loss 21293372

Variation tolerance for ZNF845 Gene

Residual Variation Intolerance Score: 93% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.24; 76.21% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF845 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF845 Gene

Disorders for ZNF845 Gene

Additional Disease Information for ZNF845

No disorders were found for ZNF845 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF845 Gene

Publications for ZNF845 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58

Products for ZNF845 Gene

Sources for ZNF845 Gene

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